{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T23:56:02Z","timestamp":1773014162881,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100001782","name":"University of Melbourne","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001782","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015988","name":"Norman Beischer Medical Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100015988","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100015539","name":"Australian Government","doi-asserted-by":"publisher","award":["#1196010"],"award-info":[{"award-number":["#1196010"]}],"id":[{"id":"10.13039\/100015539","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Gestational diabetes (GDM) is currently diagnosed in approximately 18% of pregnancies in Australia. GDM may lead to infants being born large for gestational age (LGA), and other complications. There is currently no consensus on optimal treatment targets.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>This study aims to compare perinatal outcomes in patients with GDM when treated according to tighter or less tight fasting blood glucose level (BGL) targets.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Our retrospective cohort study included data from all 12 metropolitan public hospitals providing maternity care in Victoria between January 2020 and December 2022. Women who gave birth to a term singleton infant and who had a diagnosis of GDM were included. Women were grouped according to their delivery hospitals' fasting BGL targets: \u2018tighter\u2019 (&lt;\u20095.0\u20135.2\u2009mmol\/L) or \u2018less tight\u2019 (&lt;\u20095.5\u20135.6\u2009mmol\/L). The primary outcome was LGA and a range of secondary outcomes were compared. Inverse probability treatment weights were calculated based on sociodemographic and socioeconomic factors. We then performed multilevel Poisson regression with delivery hospitals as random intercept.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There were 25\u2009041 births included, 12\u2009423 (49.6%) in the \u2018tighter\u2019 target group, and 12\u2009618 (50.4%) in the \u2018less tight\u2019 group. After adjusting for hospital and maternal demographics, there was no difference in LGA births (10.4% in \u2018tighter\u2019 vs. 9.5% in \u2018less tight\u2019 (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.85)). More women received insulin treatment in the \u2018tighter\u2019 group (53%) compared to \u2018less tight\u2019 (35%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). There were no significant differences in secondary outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Tighter fasting BGL targets were not associated with improved perinatal outcomes but were associated with an increase in pharmacotherapy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ajo.70059","type":"journal-article","created":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T11:53:38Z","timestamp":1754049218000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Perinatal Outcomes According to Treatment Targets for Gestational Diabetes: A Multi\u2010Centre Retrospective Cohort Study"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2048-4316","authenticated-orcid":false,"given":"Stephanie L.","family":"Montalto","sequence":"first","affiliation":[{"name":"Mercy Health  Heidelberg Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2696-7335","authenticated-orcid":false,"given":"Melvin","family":"Marzan","sequence":"additional","affiliation":[{"name":"University of Melbourne  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Houlihan","sequence":"additional","affiliation":[{"name":"Mercy Health  Heidelberg Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9720-3562","authenticated-orcid":false,"given":"Lisa","family":"Hui","sequence":"additional","affiliation":[{"name":"University of Melbourne  Melbourne Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel L.","family":"Rolnik","sequence":"additional","affiliation":[{"name":"Monash Health  Clayton Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sarah","family":"Price","sequence":"additional","affiliation":[{"name":"Royal Women's Hospital  Parkville Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6263-0030","authenticated-orcid":false,"given":"Joanne","family":"Said","sequence":"additional","affiliation":[{"name":"Western Health  Sunshine Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgia","family":"Soldatos","sequence":"additional","affiliation":[{"name":"Monash Health  Clayton Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Penelope","family":"Sheehan","sequence":"additional","affiliation":[{"name":"Eastern Health  Box Hill Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9719-5753","authenticated-orcid":false,"given":"Alexis","family":"Shub","sequence":"additional","affiliation":[{"name":"Mercy Health  Heidelberg Victoria Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,8,1]]},"reference":[{"key":"e_1_2_8_2_1","volume-title":"Diabetes: Australian Facts","author":"Australian Institute of Health and 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