{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T23:55:57Z","timestamp":1773014157851,"version":"3.50.1"},"reference-count":30,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T00:00:00Z","timestamp":1763683200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T00:00:00Z","timestamp":1763683200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Installation of hyaluronic acid following hysteroscopic adhesiolysis is suggested to reduce intrauterine adhesion (IUA) reformation in women with Asherman's Syndrome (AS). We aimed to assess the impact of hyaluronic acid following hysteroscopic adhesiolysis on menstrual, surgical, fertility, obstetric and neonatal outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We identified 128 women treated hysteroscopically for AS over an 11\u2010year period and invited them to participate in a questionnaire\u2010based study. A total of 43 women were included; 21 treated surgically with hyaluronic acid administered immediately following adhesiolysis and 22 having surgery alone. Outcomes were assessed by reviewing medical records retrospectively and using a structured questionnaire at 3\u2009months and 4\u2009years post procedure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      There were no differences in the rates of repeat adhesiolysis procedures to treat recurrent IUAs between the treatment and control groups (19% vs. 18%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.94). All women in the treatment group reported resumption of menses 6\u2009months following the procedure, with 9% in the control group reported ongoing amenorrhoea. There was no difference in the overall pregnancy rate (77% vs. 81%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.76), maternal and neonatal outcomes between the groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Intrauterine application of hyaluronic acid at the time of hysteroscopic adhesiolysis for women with AS was not associated with the number of repeat surgical interventions, menstrual patterns, fertility, obstetric, or neonatal outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ajo.70071","type":"journal-article","created":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T09:06:01Z","timestamp":1763715961000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Fertility and Obstetric Outcomes in Asherman Syndrome: Assessing the Impact of Hyaluronic Acid Post\u2010Hysteroscopic Adhesiolysis"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-2055-6026","authenticated-orcid":false,"given":"Georgina","family":"Armstrong","sequence":"first","affiliation":[{"name":"Gynaecological Research and Clinical Evaluation (GRACE) Group, Royal Hospital for Women  Randwick New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4406-3121","authenticated-orcid":false,"given":"Jason","family":"Abbott","sequence":"additional","affiliation":[{"name":"Gynaecological Research and Clinical Evaluation (GRACE) Group, Royal Hospital for Women  Randwick New South Wales Australia"},{"name":"School of Clinical Medicine University of New South Wales  Randwick New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7932-550X","authenticated-orcid":false,"given":"Rebecca","family":"Deans","sequence":"additional","affiliation":[{"name":"Gynaecological Research and Clinical Evaluation (GRACE) Group, Royal Hospital for Women  Randwick New South Wales Australia"},{"name":"School of Clinical Medicine University of New South Wales  Randwick New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,21]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.1950.tb06053.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2021.05.099"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/14.5.1230"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s10397-017-1007-3"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10295-014-1555-8"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deg368"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/GMIT.GMIT_103_19"},{"key":"e_1_2_7_9_1","first-page":"32","article-title":"Prevention of Intrauterine Adhesion With Auto\u2010Crosslinked Hyaluronic Acid Gel: A Prospective, Randomized, Controlled Clinical Study","volume":"50","author":"Xiao S.","year":"2015","journal-title":"Zhonghua Fu Chan Ke Za Zhi"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm13010073"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-019-05368-6"},{"key":"e_1_2_7_12_1","article-title":"New Crosslinked Hyaluronan Gel, Intrauterine Device, or Both for the Prevention of Intrauterine Adhesions","volume":"23","author":"Pabuccu E. 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