{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T07:09:15Z","timestamp":1784790555334,"version":"3.55.0"},"reference-count":24,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T00:00:00Z","timestamp":1774483200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T00:00:00Z","timestamp":1774483200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>COVID\u201019 infection during pregnancy has been associated with adverse outcomes; however, most investigations were conducted early in the pandemic. The high rates of vaccination in Western Australia during peak transmission present a unique opportunity to reassess the impact of COVID\u201019 infection in pregnancy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>This study aimed to investigate the impact of COVID\u201019 infection in pregnancy on adverse obstetric and neonatal outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>The retrospective case\u2013control study conducted at a tertiary centre in Western Australia compared COVID\u201019 positive and negative pregnancies from March to November 2022. Data from 404 participants (223 positive and 181 negative participants) were analysed. Bivariate and multivariate analyses, adjusted for confounders, were used to assess adverse outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      COVID\u201019 infection was significantly associated with lower cord blood pH (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.012); but no other adverse obstetric or neonatal outcomes (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05). Among COVID\u201019 positive cases, the timing of infection by trimester did not significantly impact adverse outcomes. However, a shorter interval between COVID\u201019 infection and delivery was associated with higher rates of caesarean sections (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.018) and neonatal comorbidities (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.007). Analysis of COVID\u201019 severity on outcomes was limited by the small sample size (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20094).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>COVID\u201019 infection during pregnancy was not associated with clinically significant adverse outcomes, likely influenced by the predominant Omicron strain and high vaccination rates. Limitations of this study included lack of universal screening and a small sample size. Notwithstanding, this study provides valuable insights that reflect the current COVID\u201019 landscape, underscoring the need for an updated understanding as context surrounding COVID\u201019 infection evolves.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ajo.70110","type":"journal-article","created":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T11:07:49Z","timestamp":1774523269000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The Effect of\n                    <scp>COVID<\/scp>\n                    \u201019 During Pregnancy on Obstetric and Neonatal Outcomes: A Retrospective Case\u2013Control Study"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-4908-2696","authenticated-orcid":false,"given":"Laura","family":"McDuff","sequence":"first","affiliation":[{"name":"School of Medicine University of Notre Dame Fremantle  Perth Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4387-7238","authenticated-orcid":false,"given":"Patricia","family":"de Gouveia Belinelo","sequence":"additional","affiliation":[{"name":"School of Medicine and Public Health\/Research University of Notre Dame Fremantle  Perth Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Lawrance","sequence":"additional","affiliation":[{"name":"School of Psychological Science University of Western Australia  Perth Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7042-9246","authenticated-orcid":false,"given":"Shailender","family":"Mehta","sequence":"additional","affiliation":[{"name":"Neonatology, Fiona Stanley Hospital  Perth Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gargeswari","family":"Sunanda","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynaecology, Fiona Stanley Hospital  Perth Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,26]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00024.2020"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/v12020194"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.13329"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.14015"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa1411"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2020.04.013"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-022-04395-7"},{"key":"e_1_2_9_9_1","unstructured":"Authority WCC \u201cGuide to Major Eleventh Edition Changes: Obstetrics Neonates and Genitourinary \u201d WA Clinical Coding Authority (2020)."},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.20272"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2017.01.049"},{"key":"e_1_2_9_12_1","unstructured":"World Health Organization \u201cClinical Management of COVID\u201019 \u201d WHO (2022)."},{"key":"e_1_2_9_13_1","unstructured":"National Institutes of Health \u201cClinical Spectrum of SARS\u2010CoV\u20102 Infection. 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