{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T04:47:41Z","timestamp":1782276461160,"version":"3.54.5"},"reference-count":23,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:00:00Z","timestamp":1777507200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:00:00Z","timestamp":1777507200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/100015988","name":"Norman Beischer Medical Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100015988","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cytomegalovirus (CMV) is the most common congenital infection and a leading preventable cause of neurodevelopmental disability. Contemporary maternal CMV seroprevalence estimates are needed to inform antenatal screening policy in Australia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>To estimate CMV seroprevalence among women referred for antenatal care at a tertiary maternity hospital, identify clinical and sociodemographic associations with serostatus, and model national and hospital\u2010level seroprevalence by maternal country of birth.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>CMV serology results from GP antenatal referrals to a Melbourne tertiary hospital over 13\u2009months were analysed. Seroprevalence was stratified by maternal country of birth, grouped by Organisation for Economic Co\u2010operation and Development (OECD) membership. National and hospital\u2010specific seroprevalence were modelled using Australian Bureau of Statistics and research dataset country\u2010of\u2010birth distributions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 4377 referrals, 591 (12.5%) included CMV serology; 61.3% were CMV IgG positive. Median gestational age at testing was 5.4\u2009weeks; referral occurred at a median of 9\u2009weeks. Seroprevalence was higher among women born in non\u2010OECD countries (86.6%) versus OECD countries (54.3%) (adjusted OR 6.44,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001). Modelled national maternal seroprevalence was 63.6%. Across Melbourne public hospitals, estimates ranged from 60% to 74%, reflecting demographic variation. Among 328 women tested for CMV IgM, 17 (5.2%) had positive or equivocal results; one had low avidity IgG, consistent with recent primary infection.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Maternal CMV seroprevalence in this cohort is higher than previously reported and strongly associated with maternal country of birth. These data inform evaluation of antenatal CMV screening feasibility and cost\u2010effectiveness studies in Australia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ajo.70142","type":"journal-article","created":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T13:20:11Z","timestamp":1777555211000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Modelling Maternal Cytomegalovirus Seroprevalence in Australia Using Maternal Country of Birth: Implications for Antenatal Screening"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2696-7335","authenticated-orcid":false,"given":"Melvin Barrientos","family":"Marzan","sequence":"first","affiliation":[{"name":"Mercy Hospital for Women  Heidelberg Victoria Australia"},{"name":"Department of Obstetrics, Gynaecology and Newborn Health University of Melbourne  Melbourne Australia"},{"name":"Reproductive Epidemiology Group, Murdoch Children's Research Institute  Melbourne Australia"},{"name":"Prevention Innovation Group, Murdoch Children's Research Institute  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7490-6310","authenticated-orcid":false,"given":"Tanya","family":"Tripathi","sequence":"additional","affiliation":[{"name":"Mercy Hospital for Women  Heidelberg Victoria Australia"},{"name":"Department of Obstetrics, Gynaecology and Newborn Health University of Melbourne  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liv","family":"Dumville","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Gynaecology and Newborn Health University of Melbourne  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo","family":"Watson","sequence":"additional","affiliation":[{"name":"Mercy Hospital for Women  Heidelberg Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8501-4054","authenticated-orcid":false,"given":"Natasha","family":"Holmes","sequence":"additional","affiliation":[{"name":"Mercy Hospital for Women  Heidelberg Victoria Australia"},{"name":"Department of Obstetrics, Gynaecology and Newborn Health University of Melbourne  Melbourne Australia"},{"name":"Austin Health  Melbourne Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9720-3562","authenticated-orcid":false,"given":"Lisa","family":"Hui","sequence":"additional","affiliation":[{"name":"Mercy Hospital for Women  Heidelberg Victoria Australia"},{"name":"Department of Obstetrics, Gynaecology and Newborn Health University of Melbourne  Melbourne Australia"},{"name":"Reproductive Epidemiology Group, Murdoch Children's Research Institute  Melbourne Australia"},{"name":"Department of Obstetrics and Gynaecology The Northern Hospital  Epping Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,30]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.20736"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2020.05.038"},{"key":"e_1_2_11_4_1","unstructured":"Australian Living Evidence Collaboration A \u201cPregnancy and Postnatal Care \u201d(2025) https:\/\/livingevidence.org.au\/living\u2010guidelines\/leapp\/."},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/uog.26136"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.43.9.4713-4718.2005"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/ajo.13645"},{"key":"e_1_2_11_8_1","volume-title":"Socio\u2010Economic Indexes for Areas (SEIFA), Australia","author":"Australian Bureau of Statistics, A","year":"2021"},{"key":"e_1_2_11_9_1","unstructured":"OECD 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