{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T10:41:31Z","timestamp":1787568091629,"version":"build-2736575974"},"reference-count":27,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T00:00:00Z","timestamp":1786752000000},"content-version":"vor","delay-in-days":14,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["obgyn.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Aust NZ J Obst Gynaeco"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Adjunct therapies are defined by regulatory bodies as non\u2010essential treatments of uncertain clinical value that may be offered alongside established fertility interventions. Despite ongoing debate regarding their cost, potential adverse effects and lack of proven benefit, many patients' undergoing in\u00a0vitro fertilisation (IVF) remain interested in trying alternative or complementary options to improve their chances of success.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Aims<\/jats:title>\n                    <jats:p>To explore the key factors influencing women's decisions to consider or use adjunct therapies during IVF treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>An anonymous online survey was distributed to women in Australia who had considered or used adjunct therapies as part of their IVF journey. Respondents provided information on the types of adjuncts used, their perceived benefits and risks, sources of information and factors influencing decision\u2010making.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 99 participants completed the survey. Most participants (94%,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200993) used or considered adjuncts such as acupuncture and nutritional supplements, valuing perceived benefits and a sense of control despite limited scientific evidence of efficacy or safety. While many acknowledged the lack of robust data, few were deterred by this, highlighting the emotional and psychological drivers of decision\u2010making. However, participants still valued accessible, independent information sources and open, empathetic discussions with clinicians.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Women undergoing IVF frequently consider and use adjunct therapies and report feeling well informed about their use, despite limited high\u2010quality evidence supporting efficacy. Cost, risk and lack of proven benefit appear to have minimal influence on decision\u2010making in the surveyed cohort. Given the ongoing and widespread interest in these treatments, clinicians should remain informed and open to discussing adjunct therapies to facilitate balanced, evidence\u2010based and patient\u2010centred decision\u2010making.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ajo.70172","type":"journal-article","created":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T09:30:18Z","timestamp":1786786218000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Women's Perspectives on Adjunct Therapies in\n                    <scp>IVF<\/scp>\n                    : Key Considerations and Influences"],"prefix":"10.1111","volume":"66","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3360-2097","authenticated-orcid":false,"given":"Gillian","family":"Homan","sequence":"first","affiliation":[{"name":"Repromed  Adelaide South Australia Australia"},{"name":"Compass Fertility  Canberra Australian Capital Territory Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carole","family":"Tilbrook","sequence":"additional","affiliation":[{"name":"Repromed  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelton","family":"Tremellen","sequence":"additional","affiliation":[{"name":"Repromed  Adelaide South Australia Australia"},{"name":"Department of Obstetrics &amp; Gynaecology and Reproductive Medicine Flinders University  Adelaide South Australia Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,8,15]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"\u201cHFEA \u201dhttps:\/\/www.hfea.gov.uk\/treatments\/treatment\u2010add\u2010ons\/. (2025)."},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2019.09.019"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/03009734.2020.1751751"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deab098"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1479-828X.2007.00702.x"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-022-02410-6"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2019.10.011"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dead184"},{"key":"e_1_2_7_10_1","unstructured":"\u201cTrusted Information for Patients About IVF Optional Extras \u201dhttps:\/\/www.unimelb.edu.au\/ivf. (2025)."},{"key":"e_1_2_7_11_1","unstructured":"\u201cNational Patient Survey 2024 \u201dhttps:\/\/www.hfea.gov.uk\/about\u2010us\/publications\/research\u2010and\u2010data\/national\u2010patient\u2010survey\u20102024."},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2022-069146"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1530\/RAF-22-0136"},{"key":"e_1_2_7_14_1","unstructured":"\u201cTurn Curiosity Into Clarity \u201dhttps:\/\/www.surveymonkey.com\/. (2024)."},{"issue":"7","key":"e_1_2_7_15_1","first-page":"1","article-title":"Foundations of Behavioral and Experimental Economics","volume":"1","author":"Kahneman D.","year":"2002","journal-title":"Nobel Prize in Economics Documents"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2021.114317"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mpsur.2022.03.012"},{"issue":"3","key":"e_1_2_7_18_1","first-page":"371","article-title":"Ethics and IVF Add\u2010Ons: We Need to Talk About It","volume":"26","author":"Braga D. P. A. F.","year":"2022","journal-title":"JBRA Assist Reprod"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2023.103637"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0236004"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep05028"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyg.2022.1095365"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.srhc.2025.101072"},{"issue":"3","key":"e_1_2_7_24_1","first-page":"209","article-title":"The Effect of Acupuncture on the Day of Embryo Transfer on the in Vitro Fertilization Outcomes: An RCT","volume":"18","author":"Dehghani A. S.","year":"2020","journal-title":"Int J Reprod Biomed"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1089\/acu.2019.1392"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2018.12.038"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2011.03.046"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2003.06.029"}],"container-title":["Australian and New Zealand Journal of Obstetrics and Gynaecology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajo.70172","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ajo.70172","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajo.70172","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T10:13:36Z","timestamp":1787566416000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1111\/ajo.70172"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":27,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["10.1111\/ajo.70172"],"URL":"https:\/\/doi.org\/10.1111\/ajo.70172","archive":["Portico"],"relation":{},"ISSN":["0004-8666","1479-828X"],"issn-type":[{"value":"0004-8666","type":"print"},{"value":"1479-828X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"2025-11-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-13","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-08-15","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70172"}}