{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T11:43:57Z","timestamp":1773056637824,"version":"3.50.1"},"reference-count":14,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T00:00:00Z","timestamp":1649116800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Australian J Rural Health"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective(s)<\/jats:title><jats:p>The objective of the study was to validate a clinical aid to guide the assessment and management of a patient's listed beta\u2010lactam antibiotic allergy for use in rural areas of Australia.<\/jats:p><\/jats:sec><jats:sec><jats:title>Design<\/jats:title><jats:p>Rural generalists, pharmacists and junior doctors completed an online assessment of eight patient case studies using the tool.<\/jats:p><\/jats:sec><jats:sec><jats:title>Setting<\/jats:title><jats:p>The study was conducted in the Southern Downs, QLD.<\/jats:p><\/jats:sec><jats:sec><jats:title>Participants<\/jats:title><jats:p>Twenty\u2010seven rural generalists, nine pharmacists and eight junior doctors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Main outcome measures<\/jats:title><jats:p>The sensitivity of the selected allergy phenotype and management option for each case study was calculated by profession and overall. Hazardous responses were reported by management category and profession.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The sensitivity overall for phenotype selection was 82.4% (95% CI, 78.0\u201386.2) and for management 88.1% (95% CI, 84.2\u201391.2). The sensitivity for phenotype selection was lower for junior doctors than other professions 73.4% (95% CI, 60.9\u201383.7), but did not reach statistical significance (<jats:italic>p<\/jats:italic>\u00a0=\u00a00.08). A total of 10\/308 responses for management recommended the least restrictive option of direct delabelling or oral challenge, where the correct answer was skin prick testing or referral to an allergist.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion(s)<\/jats:title><jats:p>With further education the tool could be a key component of increased antimicrobial stewardship in rural areas in Australia.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ajr.12868","type":"journal-article","created":{"date-parts":[[2022,4,5]],"date-time":"2022-04-05T18:14:09Z","timestamp":1649182449000},"page":"697-701","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Assessment of the validity of the beta\u2010lactam antibiotic allergy assessment tool for use in the rural context, QLD"],"prefix":"10.1111","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7345-0465","authenticated-orcid":false,"given":"Karin R.","family":"English","sequence":"first","affiliation":[{"name":"Queensland Health  Stanthorpe Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kay","family":"Knight","sequence":"additional","affiliation":[{"name":"Queensland Health  Stanthorpe Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandra","family":"Radke","sequence":"additional","affiliation":[{"name":"Queensland Health  Stanthorpe Queensland Australia"},{"name":"Griffith University  Nathan Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bethany","family":"Sammells","sequence":"additional","affiliation":[{"name":"Queensland Health  Stanthorpe Queensland Australia"},{"name":"Griffith University  Nathan Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire","family":"Walter","sequence":"additional","affiliation":[{"name":"Queensland Health  Stanthorpe Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Halliday","sequence":"additional","affiliation":[{"name":"Queensland Health  Stanthorpe Queensland Australia"},{"name":"Griffith University  Nathan Queensland Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2022,4,5]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkv159"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.5694\/mja13.10422"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-015-1303-3"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/imj.13223"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2017.12.139"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.6510"},{"key":"e_1_2_10_8_1","unstructured":"House of Representatives Standing Committee on Health Aged Care and Sport.Walking the allergy tightrope: addressing the rise of allergies and anaphylaxis in Australia. Canberra:Commonwealth of Australia;2020[cited 2020 Sep 20]. Available from:https:\/\/www.aph.gov.au\/Parliamentary_Business\/Committees\/House\/Health_Aged_Care_and_Sport\/Allergiesandanaphylaxis\/Report"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2014.11.002"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/1742-6723.12774"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2018.12.083"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cix244"},{"key":"e_1_2_10_13_1","unstructured":"Australian College of Rural and Remote Medicine.The Collingrove agreement.2018[cited 2020 Sep 20]. 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