{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T03:54:06Z","timestamp":1791518046508,"version":"4.3.4"},"reference-count":30,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2014,2,1]],"date-time":"2014-02-01T00:00:00Z","timestamp":1391212800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,2,1]],"date-time":"2014-02-01T00:00:00Z","timestamp":1391212800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,11,24]],"date-time":"2022-11-24T00:00:00Z","timestamp":1669248000000},"content-version":"vor","delay-in-days":3218,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"2011 ASTS Pfizer Collaborative Scientist"}],"content-domain":{"domain":["amjtransplant.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Transplantation"],"published-print":{"date-parts":[[2014,2]]},"DOI":"10.1111\/ajt.12588","type":"journal-article","created":{"date-parts":[[2013,12,26]],"date-time":"2013-12-26T09:54:38Z","timestamp":1388051678000},"page":"416-427","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":167,"title":["Human Microbiota Characterization in the Course of Renal Transplantation"],"prefix":"10.1016","volume":"14","author":[{"given":"W.F.","family":"Fricke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Maddox","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.S.","family":"Bromberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1111\/ajt.12588_bib1","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/S0891-5520(05)70158-6","article-title":"Infectious complications of solid organ transplantations","volume":"15","author":"Simon","year":"2001","journal-title":"Infect Dis Clin North Am"},{"key":"10.1111\/ajt.12588_bib2","doi-asserted-by":"crossref","first-page":"S4554","DOI":"10.1073\/pnas.1000087107","article-title":"Incomplete recovery and individualized responses of the human distal gut microbiota to repeated antibiotic perturbation","volume":"108","author":"Dethlefsen","year":"2011","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1111\/ajt.12588_bib3","doi-asserted-by":"crossref","first-page":"e1000255","DOI":"10.1371\/journal.pgen.1000255","article-title":"Exploring microbial diversity and taxonomy using SSU rRNA hypervariable tag sequencing","volume":"4","author":"Huse","year":"2008","journal-title":"PLoS Genet"},{"key":"10.1111\/ajt.12588_bib4","doi-asserted-by":"crossref","first-page":"S4578","DOI":"10.1073\/pnas.1000081107","article-title":"Succession of microbial consortia in the developing infant gut microbiome","volume":"108","author":"Koenig","year":"2011","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1111\/ajt.12588_bib5","doi-asserted-by":"crossref","first-page":"e9836","DOI":"10.1371\/journal.pone.0009836","article-title":"Short-term antibiotic treatment has differing long-term impacts on the human throat and gut microbiome","volume":"5","author":"Jakobsson","year":"2010","journal-title":"PLoS ONE"},{"key":"10.1111\/ajt.12588_bib6","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1034\/j.1399-302X.2003.180106.x","article-title":"Subgingival microbiota of renal transplant recipients","volume":"18","author":"Leung","year":"2003","journal-title":"Oral Microbiol Immunol"},{"key":"10.1111\/ajt.12588_bib7","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.tripleo.2005.08.004","article-title":"Evaluation of subgingival bacterial plaque changes and effects on periodontal tissues in patients with renal transplants under immunosuppressive therapy","volume":"101","author":"Saraiva","year":"2006","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1111\/ajt.12588_bib8","first-page":"286","article-title":"Oral health status, oral microflora, and non-surgical periodontal treatment of renal transplant patients receiving cyclosporin A and FK506","volume":"15","author":"Chu","year":"2000","journal-title":"Ann R Australas Coll Dent Surg"},{"key":"10.1111\/ajt.12588_bib9","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1086\/340867","article-title":"The impact of novel immunosuppressive agents on infections in organ transplant recipients and the interactions of these agents with antimicrobials","volume":"35","author":"Husain","year":"2002","journal-title":"Clin Infect Dis"},{"key":"10.1111\/ajt.12588_bib10","doi-asserted-by":"crossref","first-page":"2461","DOI":"10.1128\/AEM.02272-07","article-title":"Critical evaluation of two primers commonly used for amplification of bacterial 16S rRNA genes","volume":"74","author":"Frank","year":"2008","journal-title":"Appl Environ Microbiol"},{"key":"10.1111\/ajt.12588_bib11","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1186\/1471-2105-12-356","article-title":"CloVR: A virtual machine for automated and portable sequence analysis from the desktop using cloud computing","volume":"12","author":"Angiuoli","year":"2011","journal-title":"BMC Bioinformatics"},{"key":"10.1111\/ajt.12588_bib12","doi-asserted-by":"crossref","first-page":"2194","DOI":"10.1093\/bioinformatics\/btr381","article-title":"UCHIME improves sensitivity and speed of chimera detection","volume":"27","author":"Edgar","year":"2011","journal-title":"Bioinformatics"},{"key":"10.1111\/ajt.12588_bib13","doi-asserted-by":"crossref","first-page":"5261","DOI":"10.1128\/AEM.00062-07","article-title":"Naive Bayesian classifier for rapid assignment of rRNA sequences into the new bacterial taxonomy","volume":"73","author":"Wang","year":"2007","journal-title":"Appl Environ Microbiol"},{"key":"10.1111\/ajt.12588_bib14","doi-asserted-by":"crossref","first-page":"7537","DOI":"10.1128\/AEM.01541-09","article-title":"Introducing mothur: Open-source, platform-independent, community-supported software for describing and comparing microbial communities","volume":"75","author":"Schloss","year":"2009","journal-title":"Appl Environ Microbiol"},{"key":"10.1111\/ajt.12588_bib15","doi-asserted-by":"crossref","first-page":"e1000352","DOI":"10.1371\/journal.pcbi.1000352","article-title":"Statistical methods for detecting differentially abundant features in clinical metagenomic samples","volume":"5","author":"White","year":"2009","journal-title":"PLoS Comput Biol"},{"key":"10.1111\/ajt.12588_bib16","article-title":"Development of a multilocus sequence typing scheme for Ureaplasma","author":"Zhang","year":"2013","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1111\/ajt.12588_bib17","doi-asserted-by":"crossref","first-page":"e36298","DOI":"10.1371\/journal.pone.0036298","article-title":"Bacterial communities of the coronal sulcus and distal urethra of adolescent males","volume":"7","author":"Nelson","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1111\/ajt.12588_bib18","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1038\/nrmicro2537","article-title":"The skin microbiome","volume":"9","author":"Grice","year":"2011","journal-title":"Nat Rev Microbiol"},{"key":"10.1111\/ajt.12588_bib19","doi-asserted-by":"crossref","first-page":"1694","DOI":"10.1126\/science.1177486","article-title":"Bacterial community variation in human body habitats across space and time","volume":"326","author":"Costello","year":"2009","journal-title":"Science"},{"key":"10.1111\/ajt.12588_bib20","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1186\/1479-5876-10-174","article-title":"Integrated next-generation sequencing of 16S rDNA and metaproteomics differentiate the healthy urine microbiome from asymptomatic bacteriuria in neuropathic bladder associated with spinal cord injury","volume":"10","author":"Fouts","year":"2012","journal-title":"J Transl Med"},{"key":"10.1111\/ajt.12588_bib21","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1126\/scitranslmed.3003605","article-title":"Temporal dynamics of the human vaginal microbiota","volume":"4","author":"Gajer","year":"2012","journal-title":"Sci Transl Med"},{"key":"10.1111\/ajt.12588_bib22","doi-asserted-by":"crossref","first-page":"530","DOI":"10.4161\/gmic.22157","article-title":"Differences in microbial signatures between rectal mucosal biopsies and rectal swabs","volume":"3","author":"Araujo-Perez","year":"2012","journal-title":"Gut Microbes"},{"key":"10.1111\/ajt.12588_bib23","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1128\/JCM.05852-11","article-title":"Evidence of uncultivated bacteria in the adult female bladder","volume":"50","author":"Wolfe","year":"2012","journal-title":"J Clin Microbiol"},{"key":"10.1111\/ajt.12588_bib24","doi-asserted-by":"crossref","first-page":"2366","DOI":"10.1172\/JCI66451","article-title":"Bacterial control of host gene expression through RNA polymerase II","volume":"123","author":"Lutay","year":"2013","journal-title":"J Clin Invest"},{"key":"10.1111\/ajt.12588_bib25","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1128\/CVI.00734-12","article-title":"Transplantation-associated long-term immunosuppression promotes oral colonization by potentially opportunistic pathogens without impacting other members of the salivary bacteriome","volume":"20","author":"Diaz","year":"2013","journal-title":"Clin Vaccine Immunol"},{"key":"10.1111\/ajt.12588_bib26","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1111\/j.1600-6143.2011.03860.x","article-title":"Characterization of the ileal microbiota in rejecting and nonrejecting recipients of small bowel transplants","volume":"12","author":"Oh","year":"2012","journal-title":"Am J Transplant"},{"key":"10.1111\/ajt.12588_bib27","doi-asserted-by":"crossref","first-page":"e23503","DOI":"10.1371\/journal.pone.0023503","article-title":"Comparative analysis of salivary bacterial microbiome diversity in edentulous infants and their mothers or primary care givers using pyrosequencing","volume":"6","author":"Cephas","year":"2011","journal-title":"PLoS ONE"},{"key":"10.1111\/ajt.12588_bib28","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1086\/525047","article-title":"Decreased diversity of the fecal Microbiome in recurrent Clostridium difficile-associated diarrhea","volume":"197","author":"Chang","year":"2008","journal-title":"J Infect Dis"},{"key":"10.1111\/ajt.12588_bib29","doi-asserted-by":"crossref","first-page":"1844","DOI":"10.1053\/j.gastro.2010.08.049","article-title":"A pyrosequencing study in twins shows that gastrointestinal microbial profiles vary with inflammatory bowel disease phenotypes","volume":"139","author":"Willing","year":"2010","journal-title":"Gastroenterology"},{"key":"10.1111\/ajt.12588_bib30","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.chom.2008.02.015","article-title":"Diet-induced obesity is linked to marked but reversible alterations in the mouse distal gut microbiome","volume":"3","author":"Turnbaugh","year":"2008","journal-title":"Cell Host Microbe"}],"container-title":["American Journal of Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fajt.12588","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fajt.12588","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613522253453?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613522253453?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/ajt.12588\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:04:20Z","timestamp":1761627860000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1600613522253453"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2014,2]]}},"alternative-id":["S1600613522253453"],"URL":"https:\/\/doi.org\/10.1111\/ajt.12588","relation":{},"ISSN":["1600-6135"],"issn-type":[{"value":"1600-6135","type":"print"}],"subject":[],"published":{"date-parts":[[2014,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Human Microbiota Characterization in the Course of Renal Transplantation","name":"articletitle","label":"Article Title"},{"value":"American Journal of Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1111\/ajt.12588","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. All rights reserved. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}