{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T10:57:13Z","timestamp":1790506633666,"version":"4.1.0"},"reference-count":31,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T00:00:00Z","timestamp":1396310400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,4,1]],"date-time":"2014-04-01T00:00:00Z","timestamp":1396310400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,11,23]],"date-time":"2022-11-23T00:00:00Z","timestamp":1669161600000},"content-version":"vor","delay-in-days":3158,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["amjtransplant.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Transplantation"],"published-print":{"date-parts":[[2014,4]]},"DOI":"10.1111\/ajt.12631","type":"journal-article","created":{"date-parts":[[2014,2,20]],"date-time":"2014-02-20T08:53:34Z","timestamp":1392886414000},"page":"841-848","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":42,"title":["Bile Acid Aspiration Associated With Lung Chemical Profile Linked to Other Biomarkers of Injury After Lung Transplantation"],"prefix":"10.1016","volume":"14","author":[{"given":"D.C.","family":"Neujahr","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Uppal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.D.","family":"Force","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Fernandez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Lawrence","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Pickens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Bag","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Lockard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.D.","family":"Kirk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Tran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.P.","family":"Jones","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1111\/ajt.12631_bib1","doi-asserted-by":"crossref","first-page":"1144","DOI":"10.1016\/j.jtcvs.2004.10.035","article-title":"Bile acid aspiration and the development of bronchiolitis obliterans after lung transplantation","volume":"129","author":"D\u2019Ovidio","year":"2005","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1111\/ajt.12631_bib2","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1111\/j.1600-6143.2010.03380.x","article-title":"Bile acids aspiration reduces survival in lung transplant recipients with BOS despite azithromycin","volume":"11","author":"Mertens","year":"2011","journal-title":"Am J Transplant"},{"key":"10.1111\/ajt.12631_bib3","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1164\/rccm.200610-1485OC","article-title":"Pepsin, a biomarker of gastric aspiration in lung allografts: A putative association with rejection","volume":"175","author":"Stovold","year":"2007","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1111\/ajt.12631_bib4","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.jtcvs.2005.06.054","article-title":"Chronic aspiration of gastric fluid accelerates pulmonary allograft dysfunction in a rat model of lung transplantation","volume":"131","author":"Hartwig","year":"2006","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1111\/ajt.12631_bib5","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1111\/j.1600-6143.2008.02298.x","article-title":"Chronic aspiration of gastric fluid induces the development of obliterative bronchiolitis in rat lung transplants","volume":"8","author":"Li","year":"2008","journal-title":"Am J Transplant"},{"key":"10.1111\/ajt.12631_bib6","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.tox.2012.02.007","article-title":"High-performance metabolic profiling of plasma from seven mammalian species for simultaneous environmental chemical surveillance and bioeffect monitoring","volume":"295","author":"Park","year":"2012","journal-title":"Toxicology"},{"key":"10.1111\/ajt.12631_bib7","doi-asserted-by":"crossref","first-page":"1930","DOI":"10.1093\/bioinformatics\/btp291","article-title":"apLCMS-adaptive processing of high-resolution LC\/MS data","volume":"25","author":"Yu","year":"2009","journal-title":"Bioinformatics"},{"key":"10.1111\/ajt.12631_bib8","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1146\/annurev-nutr-072610-145159","article-title":"Nutritional metabolomics: Progress in addressing complexity in diet and health","volume":"32","author":"Jones","year":"2012","journal-title":"Annu Rev Nutr"},{"key":"10.1111\/ajt.12631_bib9","doi-asserted-by":"crossref","first-page":"2864","DOI":"10.1039\/c0an00333f","article-title":"A practical approach to detect unique metabolic patterns for personalized medicine","volume":"135","author":"Johnson","year":"2010","journal-title":"Analyst"},{"key":"10.1111\/ajt.12631_bib10","doi-asserted-by":"crossref","first-page":"e33020","DOI":"10.1371\/journal.pone.0033020","article-title":"Detailed mitochondrial phenotyping by high resolution metabolomics","volume":"7","author":"Roede","year":"2012","journal-title":"PLoS ONE"},{"issue":"1 Suppl","key":"10.1111\/ajt.12631_bib11","first-page":"132","article-title":"High-performance metabolic profiling with dual chromatography-Fourier-transform mass spectrometry (DC-FTMS) for study of the exposome","volume":"9","author":"Soltow","year":"2011","journal-title":"Metabolomics"},{"key":"10.1111\/ajt.12631_bib12","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1111\/j.1600-6143.2011.03857.x","article-title":"Cumulative exposure to gamma interferon-dependent chemokines CXCL9 and CXCL10 correlates with worse outcome after lung transplant","volume":"12","author":"Neujahr","year":"2012","journal-title":"Am J Transplant"},{"key":"10.1111\/ajt.12631_bib13","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1097\/TP.0b013e3181b0e719","article-title":"Dynamics of human regulatory T cells in lung lavages of lung transplant recipients","volume":"88","author":"Neujahr","year":"2009","journal-title":"Transplantation"},{"key":"10.1111\/ajt.12631_bib14","doi-asserted-by":"crossref","first-page":"3892","DOI":"10.1016\/j.transproceed.2011.09.072","article-title":"Cumulative exposure to CD8+ granzyme Bhi T cells is associated with reduced lung function early after lung transplantation","volume":"43","author":"Mohammed","year":"2011","journal-title":"Transplant Proc"},{"key":"10.1111\/ajt.12631_bib15","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1164\/rccm.200601-071OC","article-title":"Azithromycin reduces airway neutrophilia and interleukin-8 in patients with bronchiolitis obliterans syndrome","volume":"174","author":"Verleden","year":"2006","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1111\/ajt.12631_bib16","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1111\/j.1442-2050.2006.00603.x","article-title":"Gastroesophageal reflux and lung transplantation","volume":"19","author":"D\u2019Ovidio","year":"2006","journal-title":"Dis Esophagus"},{"key":"10.1111\/ajt.12631_bib17","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1034\/j.1399-0012.2003.00060.x","article-title":"Gastroesophageal reflux disease in lung transplant recipients","volume":"17","author":"Hadjiliadis","year":"2003","journal-title":"Clin Transplant"},{"key":"10.1111\/ajt.12631_bib18","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.1378\/chest.124.5.1689","article-title":"Lung transplantation exacerbates gastroesophageal reflux disease","volume":"124","author":"Young","year":"2003","journal-title":"Chest"},{"key":"10.1111\/ajt.12631_bib19","doi-asserted-by":"crossref","first-page":"e279","DOI":"10.1016\/j.jss.2011.05.038","article-title":"Laparoscopic antireflux surgery for gastroesophageal reflux disease after lung transplantation","volume":"170","author":"Fisichella","year":"2011","journal-title":"J Surg Res"},{"key":"10.1111\/ajt.12631_bib20","doi-asserted-by":"crossref","first-page":"e65","DOI":"10.1016\/j.jss.2012.03.066","article-title":"Pulmonary immune changes early after laparoscopic antireflux surgery in lung transplant patients with gastroesophageal reflux disease","volume":"177","author":"Fisichella","year":"2012","journal-title":"J Surg Res"},{"key":"10.1111\/ajt.12631_bib21","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1111\/j.1399-0012.2011.01434.x","article-title":"Prevalence of gastroparesis before and after lung transplantation and its association with lung allograft outcomes","volume":"26","author":"Raviv","year":"2012","journal-title":"Clin Transplant"},{"key":"10.1111\/ajt.12631_bib22","doi-asserted-by":"crossref","first-page":"1930","DOI":"10.1111\/j.1600-6143.2006.01357.x","article-title":"The effect of reflux and bile acid aspiration on the lung allograft and its surfactant and innate immunity molecules SP-A and SP-D","volume":"6","author":"D\u2019Ovidio","year":"2006","journal-title":"Am J Transplant"},{"key":"10.1111\/ajt.12631_bib23","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1038\/nri1528","article-title":"Immunoregulatory functions of surfactant proteins","volume":"5","author":"Wright","year":"2005","journal-title":"Nat Rev Immunol"},{"key":"10.1111\/ajt.12631_bib24","first-page":"L540","article-title":"Surfactant protein A enhances the binding and deacylation of E. coli LPS by alveolar macrophages","volume":"276","author":"Stamme","year":"1999","journal-title":"Am J Physiol"},{"key":"10.1111\/ajt.12631_bib25","doi-asserted-by":"crossref","first-page":"G199","DOI":"10.1152\/ajpgi.00454.2011","article-title":"Bile salts disrupt human esophageal squamous epithelial barrier function by modulating tight junction proteins","volume":"303","author":"Chen","year":"2012","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1111\/ajt.12631_bib26","doi-asserted-by":"crossref","first-page":"G203","DOI":"10.1152\/ajpgi.00096.2011","article-title":"Acidic bile salts modulate the squamous epithelial barrier function by modulating tight junction proteins","volume":"301","author":"Chen","year":"2011","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"10.1111\/ajt.12631_bib27","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1016\/j.healun.2008.05.022","article-title":"Airway colonization and gastric aspiration after lung transplantation: Do birds of a feather flock together?","volume":"27","author":"Vos","year":"2008","journal-title":"J Heart Lung Transplant"},{"key":"10.1111\/ajt.12631_bib28","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.4049\/jimmunol.169.2.1037","article-title":"Critical role for CXCR3 chemokine biology in the pathogenesis of bronchiolitis obliterans syndrome","volume":"169","author":"Belperio","year":"2002","journal-title":"J Immunol"},{"key":"10.1111\/ajt.12631_bib29","doi-asserted-by":"crossref","first-page":"4844","DOI":"10.4049\/jimmunol.171.9.4844","article-title":"Role of CXCL9\/CXCR3 chemokine biology during pathogenesis of acute lung allograft rejection","volume":"171","author":"Belperio","year":"2003","journal-title":"J Immunol"},{"key":"10.1111\/ajt.12631_bib30","doi-asserted-by":"crossref","first-page":"7087","DOI":"10.4049\/jimmunol.176.11.7087","article-title":"CXCR3 and its ligands in a murine model of obliterative bronchiolitis: Regulation and function","volume":"176","author":"Medoff","year":"2006","journal-title":"J Immunol"},{"key":"10.1111\/ajt.12631_bib31","doi-asserted-by":"crossref","first-page":"2228","DOI":"10.1111\/j.1600-6143.2011.03680.x","article-title":"Urinary chemokines CXCL9 and CXCL10 are noninvasive markers of renal allograft rejection and BK viral infection","volume":"11","author":"Jackson","year":"2011","journal-title":"Am J Transplant"}],"container-title":["American Journal of Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fajt.12631","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613522254100?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613522254100?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:04:37Z","timestamp":1761627877000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1600613522254100"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,4]]},"references-count":31,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014,4]]}},"alternative-id":["S1600613522254100"],"URL":"https:\/\/doi.org\/10.1111\/ajt.12631","relation":{},"ISSN":["1600-6135"],"issn-type":[{"value":"1600-6135","type":"print"}],"subject":[],"published":{"date-parts":[[2014,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bile Acid Aspiration Associated With Lung Chemical Profile Linked to Other Biomarkers of Injury After Lung Transplantation","name":"articletitle","label":"Article Title"},{"value":"American Journal of Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1111\/ajt.12631","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. All rights reserved. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}