{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T04:17:11Z","timestamp":1791951431498,"version":"4.3.4"},"reference-count":42,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2015,6,1]],"date-time":"2015-06-01T00:00:00Z","timestamp":1433116800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,6,1]],"date-time":"2015-06-01T00:00:00Z","timestamp":1433116800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,11,19]],"date-time":"2022-11-19T00:00:00Z","timestamp":1668816000000},"content-version":"vor","delay-in-days":2728,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["MD009055"],"award-info":[{"award-number":["MD009055"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["DK084149"],"award-info":[{"award-number":["DK084149"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["DK070941"],"award-info":[{"award-number":["DK070941"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["5U19-AI070119"],"award-info":[{"award-number":["5U19-AI070119"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["amjtransplant.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Transplantation"],"published-print":{"date-parts":[[2015,6]]},"DOI":"10.1111\/ajt.13223","type":"journal-article","created":{"date-parts":[[2015,3,24]],"date-time":"2015-03-24T19:26:15Z","timestamp":1427225175000},"page":"1615-1622","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":167,"title":["Apolipoprotein L1 Gene Variants in Deceased Organ Donors Are Associated With Renal Allograft Failure"],"prefix":"10.1016","volume":"15","author":[{"given":"B.I.","family":"Freedman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B.A.","family":"Julian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.O.","family":"Pastan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.K.","family":"Israni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Schladt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.D.","family":"Gautreaux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V.","family":"Hauptfeld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.A.","family":"Bray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.M.","family":"Gebel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.D.","family":"Kirk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.S.","family":"Gaston","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Rogers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.C.","family":"Farney","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Orlando","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.J.","family":"Stratta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Mohan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.D.","family":"Langefeld","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.J.","family":"Hicks","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.D.","family":"Palmer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.L.","family":"Adams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Palanisamy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.M.","family":"Reeves-Daniel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Divers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1111\/ajt.13223_bib1","unstructured":"Department of Health and Human Services HRaSAHSBDoT. Organ procurement and transplantation network (OPTN) and scientific registry of transplant recipients (SRTR). OPTN\/SRTR 2010 Annual Data Report. Rockville, MD, 2011."},{"key":"10.1111\/ajt.13223_bib2","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1111\/ajt.12553","article-title":"Kidneys at higher risk of discard: Expanding the role of dual kidney transplantation","volume":"14","author":"Tanriover","year":"2014","journal-title":"Am J Transplant"},{"key":"10.1111\/ajt.13223_bib3","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1056\/NEJM199209173271202","article-title":"Survival of nationally shared, HLA-matched kidney transplants from cadaveric donors. The UNOS Scientific Renal Transplant Registry","volume":"327","author":"Takemoto","year":"1992","journal-title":"N Engl J Med"},{"key":"10.1111\/ajt.13223_bib4","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.semnephrol.2010.01.010","article-title":"Translating associations between common kidney diseases and genetic variation into the clinic","volume":"30","author":"Drawz","year":"2010","journal-title":"Semin Nephrol"},{"key":"10.1111\/ajt.13223_bib5","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1126\/science.1193032","article-title":"Association of trypanolytic ApoL1 variants with kidney disease in African Americans","volume":"329","author":"Genovese","year":"2010","journal-title":"Science"},{"key":"10.1111\/ajt.13223_bib6","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1007\/s00439-010-0861-0","article-title":"Missense mutations in the APOL1 gene are highly associated with end stage kidney disease risk previously attributed to the MYH9 gene","volume":"128","author":"Tzur","year":"2010","journal-title":"Hum Genet"},{"key":"10.1111\/ajt.13223_bib7","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1681\/ASN.2011040388","article-title":"APOL1 genetic variants in focal segmental glomerulosclerosis and HIV-associated nephropathy","volume":"22","author":"Kopp","year":"2011","journal-title":"J Am Soc Nephrol"},{"key":"10.1111\/ajt.13223_bib8","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1111\/j.1365-2141.2011.08832.x","article-title":"MYH9 and APOL1 are both associated with sickle cell disease nephropathy","volume":"155","author":"Ashley-Koch","year":"2011","journal-title":"Br J Haematol"},{"key":"10.1111\/ajt.13223_bib9","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1038\/ki.2012.263","article-title":"Apolipoprotein L1 gene variants associate with hypertension-attributed nephropathy and the rate of kidney function decline in African Americans","volume":"83","author":"Lipkowitz","year":"2013","journal-title":"Kidney Int"},{"key":"10.1111\/ajt.13223_bib10","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1002\/art.38220","article-title":"End-stage renal disease in African Americans with lupus nephritis is associated with APOL1","volume":"66","author":"Freedman","year":"2014","journal-title":"Arthritis Rheumatol"},{"key":"10.1111\/ajt.13223_bib11","doi-asserted-by":"crossref","first-page":"2183","DOI":"10.1056\/NEJMoa1310345","article-title":"APOL1 risk variants, race, and progression of chronic kidney disease","volume":"369","author":"Parsa","year":"2013","journal-title":"N Engl J Med"},{"key":"10.1111\/ajt.13223_bib12","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1681\/ASN.2012121180","article-title":"Apolipoprotein L1 risk variants associate with systemic lupus erythematosus-associated collapsing glomerulopathy","volume":"24","author":"Larsen","year":"2013","journal-title":"J Am Soc Nephrol"},{"key":"10.1111\/ajt.13223_bib13","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1111\/j.1365-2958.2010.07156.x","article-title":"The trypanolytic factor of human serum: many ways to enter the parasite, a single way to kill","volume":"76","author":"Vanhollebeke","year":"2010","journal-title":"Mol Microbiol"},{"key":"10.1111\/ajt.13223_bib14","doi-asserted-by":"crossref","first-page":"1422","DOI":"10.1681\/ASN.2010070730","article-title":"The apolipoprotein L1 (APOL1) gene and nondiabetic nephropathy in African Americans","volume":"21","author":"Freedman","year":"2010","journal-title":"J Am Soc Nephrol"},{"key":"10.1111\/ajt.13223_bib15","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1038\/nrneph.2013.34","article-title":"APOL1 variants and kidney disease in people of recent African ancestry","volume":"9","author":"Genovese","year":"2013","journal-title":"Nat Rev Nephrol"},{"key":"10.1111\/ajt.13223_bib16","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1111\/j.1600-6143.2011.03513.x","article-title":"The APOL1 gene and allograft survival after kidney transplantation","volume":"11","author":"Reeves-Daniel","year":"2011","journal-title":"Am J Transplant"},{"key":"10.1111\/ajt.13223_bib17","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1046\/j.1523-1755.2000.00287.x","article-title":"Effect of waiting time on renal transplant outcome","volume":"58","author":"Meier-Kriesche","year":"2000","journal-title":"Kidney Int"},{"key":"10.1111\/ajt.13223_bib18","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1034\/j.1600-6143.2002.020112.x","article-title":"Effect of donor factors on early graft survival in adult cadaveric renal transplantation","volume":"2","author":"Swanson","year":"2002","journal-title":"Am J Transplant"},{"key":"10.1111\/ajt.13223_bib19","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1681\/ASN.2004040333","article-title":"Influence of race on kidney transplant outcomes within and outside the Department of Veterans Affairs","volume":"16","author":"Chakkera","year":"2005","journal-title":"J Am Soc Nephrol"},{"key":"10.1111\/ajt.13223_bib20","doi-asserted-by":"crossref","first-page":"4125","DOI":"10.1016\/j.transproceed.2009.06.182","article-title":"Effect of donor ethnicity on kidney survival in different recipient pairs: an analysis of the OPTN\/UNOS database","volume":"41","author":"Callender","year":"2009","journal-title":"Transplant Proc"},{"key":"10.1111\/ajt.13223_bib21","doi-asserted-by":"crossref","first-page":"1924","DOI":"10.1111\/j.1600-6143.2012.04033.x","article-title":"The APOL1 genotype of African American kidney transplant recipients does not impact 5-year allograft survival","volume":"12","author":"Lee","year":"2012","journal-title":"Am J Transplant"},{"key":"10.1111\/ajt.13223_bib22","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.trre.2013.01.002","article-title":"Scientific registry of transplant recipients: Collecting, analyzing, and reporting data on transplantation in the United States","volume":"27","author":"Leppke","year":"2013","journal-title":"Transplant Rev (Orlando)"},{"key":"10.1111\/ajt.13223_bib23","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.2517-6161.1972.tb00899.x","article-title":"Regression models and life-tables","volume":"34","author":"Cox","year":"1972","journal-title":"J Royal Stat Soc, Series B"},{"key":"10.1111\/ajt.13223_bib24","series-title":"Modeling survival data: Extending the Cox model","first-page":"170","author":"Therneau","year":"2000"},{"key":"10.1111\/ajt.13223_bib25","doi-asserted-by":"crossref","first-page":"121","DOI":"10.2307\/2531248","article-title":"Longitudinal data analysis for discrete and continuous outcomes","volume":"42","author":"Zeger","year":"1986","journal-title":"Biometrics"},{"key":"10.1111\/ajt.13223_bib26","doi-asserted-by":"crossref","first-page":"1074","DOI":"10.1080\/01621459.1989.10478874","article-title":"The robust inference for the Cox Proportional Hazards Model","volume":"84","author":"Lin","year":"1989","journal-title":"J Am Stat Assoc"},{"key":"10.1111\/ajt.13223_bib27","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1080\/01621459.1999.10474144","article-title":"A proportional Hazards Model for the Subdistribution of a competing risk","volume":"94","author":"Fine","year":"1999","journal-title":"J Am Stat Assoc"},{"key":"10.1111\/ajt.13223_bib28","unstructured":"Zhou B, Latouche A. Competing risks regression for stratified and clustered data. R package version 1.1; 2013. http:\/\/CRANR-projectorg\/package=crrSC2013."},{"key":"10.1111\/ajt.13223_bib29","doi-asserted-by":"crossref","first-page":"1207","DOI":"10.1038\/ki.2013.173","article-title":"JC polyoma virus interacts with APOL1 in African Americans with nondiabetic nephropathy","volume":"84","author":"Divers","year":"2013","journal-title":"Kidney Int"},{"key":"10.1111\/ajt.13223_bib30","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.1038\/ki.2013.299","article-title":"JC viruria and kidney disease in APOL1 risk genotype individuals: Is this a clue to a gene x environment interaction?","volume":"84","author":"Kopp","year":"2013","journal-title":"Kidney Int"},{"key":"10.1111\/ajt.13223_bib31","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1093\/ndt\/gft423","article-title":"Gene-gene interactions in APOL1-associated nephropathy","volume":"29","author":"Divers","year":"2014","journal-title":"Nephrol Dial Transplant"},{"key":"10.1111\/ajt.13223_bib32","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1097\/TP.0b013e31822eec39","article-title":"African American living-kidney donors should be screened for APOL1 risk alleles","volume":"92","author":"Cohen","year":"2011","journal-title":"Transplantation"},{"key":"10.1111\/ajt.13223_bib33","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1053\/j.ajkd.2013.12.014","article-title":"APOL1 polymorphisms and development of CKD in an identical twin donor and recipient pair","volume":"63","author":"Kofman","year":"2014","journal-title":"Am J Kidney Dis"},{"key":"10.1111\/ajt.13223_bib34","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1097\/01.tp.0000277288.78771.c2","article-title":"Living kidney donors requiring transplantation: focus on African Americans","volume":"84","author":"Gibney","year":"2007","journal-title":"Transplantation"},{"key":"10.1111\/ajt.13223_bib35","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1056\/NEJMoa1000950","article-title":"Racial variation in medical outcomes among living kidney donors","volume":"363","author":"Lentine","year":"2010","journal-title":"N Engl J Med"},{"key":"10.1111\/ajt.13223_bib36","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1097\/01.TP.0000436731.23554.5e","article-title":"Consistency of racial variation in medical outcomes among publicly and privately insured living kidney donors","volume":"97","author":"Lentine","year":"2014","journal-title":"Transplantation"},{"key":"10.1111\/ajt.13223_bib37","doi-asserted-by":"crossref","first-page":"2574","DOI":"10.1111\/j.1600-6143.2010.03324.x","article-title":"Living donor nephrectomy: understanding long-term risk in minority populations","volume":"10","author":"Gaston","year":"2010","journal-title":"Am J Transplant"},{"key":"10.1111\/ajt.13223_bib38","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1111\/j.1600-6143.2010.03023.x","article-title":"\u201cNormal for now\u201d or \u201cat future risk\u201d: A double standard for selecting young and older living kidney donors","volume":"10","author":"Steiner","year":"2010","journal-title":"Am J Transplant"},{"key":"10.1111\/ajt.13223_bib39","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1056\/NEJMoa025056","article-title":"Effect of changing the priority for HLA matching on the rates and outcomes of kidney transplantation in minority groups","volume":"350","author":"Roberts","year":"2004","journal-title":"N Engl J Med"},{"key":"10.1111\/ajt.13223_bib40","doi-asserted-by":"crossref","first-page":"1776","DOI":"10.1111\/j.1600-6143.2012.04091.x","article-title":"The contribution of donor quality to differential graft survival in African American and Caucasian renal transplant recipients","volume":"12","author":"Cannon","year":"2012","journal-title":"Am J Transplant"},{"key":"10.1111\/ajt.13223_bib41","doi-asserted-by":"crossref","first-page":"562","DOI":"10.2215\/CJN.07610713","article-title":"The role of procurement biopsies in acceptance decisions for kidneys retrieved for transplant","volume":"9","author":"Kasiske","year":"2014","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1111\/ajt.13223_bib42","doi-asserted-by":"crossref","first-page":"1842","DOI":"10.1681\/ASN.2013070784","article-title":"New national allocation policy for deceased donor kidneys in the United States and possible effect on patient outcomes","volume":"25","author":"Israni","year":"2014","journal-title":"J Am Soc Nephrol"}],"container-title":["American Journal of Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fajt.13223","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613522270701?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613522270701?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:09:41Z","timestamp":1761628181000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1600613522270701"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6]]},"references-count":42,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,6]]}},"alternative-id":["S1600613522270701"],"URL":"https:\/\/doi.org\/10.1111\/ajt.13223","relation":{},"ISSN":["1600-6135"],"issn-type":[{"value":"1600-6135","type":"print"}],"subject":[],"published":{"date-parts":[[2015,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Apolipoprotein L1 Gene Variants in Deceased Organ Donors Are Associated With Renal Allograft Failure","name":"articletitle","label":"Article Title"},{"value":"American Journal of Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1111\/ajt.13223","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. All rights reserved. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}