{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:19:48Z","timestamp":1787239188701,"version":"build-2736575974"},"reference-count":29,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,2,1]],"date-time":"2017-02-01T00:00:00Z","timestamp":1485907200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,11,21]],"date-time":"2022-11-21T00:00:00Z","timestamp":1668988800000},"content-version":"vor","delay-in-days":2119,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"Consorzio per la Ricerca Sanitaria - CORIS (Consortium for Health Research, Padova, Italy)"},{"DOI":"10.13039\/501100009878","name":"Veneto Region","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100009878","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100007479","name":"Fondazione Cassa di Risparmio di Padova e Rovigo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007479","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["amjtransplant.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Transplantation"],"published-print":{"date-parts":[[2017,2]]},"DOI":"10.1111\/ajt.14053","type":"journal-article","created":{"date-parts":[[2016,9,19]],"date-time":"2016-09-19T05:29:30Z","timestamp":1474262970000},"page":"557-564","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":37,"title":["Immediate and Catastrophic Antibody-Mediated Rejection in a Lung Transplant Recipient With Anti\u2013Angiotensin II Receptor Type 1 and Anti\u2013Endothelin-1 Receptor Type A Antibodies"],"prefix":"10.1016","volume":"17","author":[{"given":"E.","family":"Cozzi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Calabrese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Schiavon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.","family":"Feltracco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Seveso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Carollo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Loy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Cardillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Rea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1111\/ajt.14053_bib1","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1111\/ajt.12589","article-title":"Diagnosis and management of antibody-mediated rejection: Current status and novel approaches","volume":"14","author":"Djamali","year":"2014","journal-title":"Am J Transplant"},{"key":"10.1111\/ajt.14053_bib2","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1097\/MNH.0000000000000069","article-title":"New insights in antibody-mediated rejection","volume":"23","author":"Gosset","year":"2014","journal-title":"Curr Opin Nephrol Hypertens"},{"key":"10.1111\/ajt.14053_bib3","doi-asserted-by":"crossref","first-page":"2334","DOI":"10.1111\/ajt.12370","article-title":"Kidney allograft survival after acute rejection, the value of follow-up biopsies","volume":"13","author":"El Ters","year":"2013","journal-title":"Am J Transplant"},{"key":"10.1111\/ajt.14053_bib4","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1161\/CIR.0000000000000093","article-title":"Antibody-mediated rejection in cardiac transplantation: Emerging knowledge in diagnosis and management: A scientific statement from the American Heart Association","volume":"131","author":"Colvin","year":"2015","journal-title":"Circulation"},{"key":"10.1111\/ajt.14053_bib5","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1016\/j.healun.2013.07.004","article-title":"Acute antibody-mediated rejection after lung transplantation","volume":"32","author":"Witt","year":"2013","journal-title":"J Heart Lung Transplant"},{"key":"10.1111\/ajt.14053_bib6","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1002\/lt.23788","article-title":"Antibody-mediated rejection as a contributor to previously unexplained early liver allograft loss","volume":"20","author":"O\u2019Leary","year":"2014","journal-title":"Liver Transpl"},{"key":"10.1111\/ajt.14053_bib7","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1681\/ASN.2014080837","article-title":"Utility of HLA antibody testing in kidney transplantation","volume":"26","author":"Konvalinka","year":"2015","journal-title":"J Am Soc Nephrol"},{"key":"10.1111\/ajt.14053_bib8","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1111\/ajt.12590","article-title":"Banff meeting report writing committee. Banff 2013 meeting report: Inclusion of c4d-negative antibody-mediated rejection and antibody-associated arterial lesions","volume":"14","author":"Haas","year":"2014","journal-title":"Am J Transplant"},{"key":"10.1111\/ajt.14053_bib9","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.healun.2016.01.1223","article-title":"Antibody-mediated rejection of the lung: A consensus report of the International Society for Heart and Lung Transplantation","volume":"35","author":"Levine","year":"2016","journal-title":"J Heart Lung Transplant"},{"key":"10.1111\/ajt.14053_bib10","doi-asserted-by":"crossref","first-page":"1721","DOI":"10.1681\/ASN.2014040399","article-title":"Subclinical rejection phenotypes at 1 year post-transplant and outcome of kidney allografts","volume":"26","author":"Loupy","year":"2015","journal-title":"J Am Soc Nephrol"},{"key":"10.1111\/ajt.14053_bib11","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.1016\/j.humimm.2013.07.001","article-title":"Moving beyond HLA: A review of nHLA antibodies in organ transplantation","volume":"74","author":"Sigdel","year":"2013","journal-title":"Hum Immunol"},{"key":"10.1111\/ajt.14053_bib12","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1056\/NEJMoa035717","article-title":"Angiotensin II type 1-receptor activating antibodies in renal-allograft rejection","volume":"352","author":"Dragun","year":"2005","journal-title":"N Engl J Med"},{"key":"10.1111\/ajt.14053_bib13","doi-asserted-by":"crossref","first-page":"2567","DOI":"10.1111\/ajt.12397","article-title":"Pretransplant sensitization against angiotensin II type 1 receptor is a risk factor for acute rejection and graft loss","volume":"13","author":"Giral","year":"2013","journal-title":"Am J Transplant"},{"key":"10.1111\/ajt.14053_bib14","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1097\/01.TP.0000436927.08026.a8","article-title":"Increased negative impact of donor HLA-specific together with non-HLA-specific antibodies on graft outcome","volume":"97","author":"Reinsmoen","year":"2014","journal-title":"Transplantation"},{"key":"10.1111\/ajt.14053_bib15","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.jcf.2014.07.007","article-title":"Anti-ETAR and anti-AT1R autoantibodies are elevated in patients with endstage cystic fibrosis","volume":"14","author":"Budding","year":"2015","journal-title":"J Cyst Fibros"},{"key":"10.1111\/ajt.14053_bib16","doi-asserted-by":"crossref","first-page":"1454","DOI":"10.1016\/j.healun.2004.11.049","article-title":"Report of the ISHLT Working Group on Primary Lung Graft Dysfunction part II: Definition. A consensus statement of the International Society for Heart and Lung Transplantation","volume":"24","author":"Christie","year":"2005","journal-title":"J Heart Lung Transplant"},{"key":"10.1111\/ajt.14053_bib17","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/j.healun.2014.09.047","article-title":"Phosphorylated S6 kinase and S6 ribosomal protein are diagnostic markers of antibody-mediated rejection in heart allografts","volume":"34","author":"Li","year":"2015","journal-title":"J Heart Lung Transplant"},{"key":"10.1111\/ajt.14053_bib18","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.trim.2014.06.004","article-title":"Evolving experience of treating antibody-mediated rejection following lung transplantation","volume":"31","author":"Otani","year":"2014","journal-title":"Transpl Immunol"},{"key":"10.1111\/ajt.14053_bib19","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1111\/nep.12441","article-title":"C4d-negative antibody-mediated rejection with high anti-angiotensin II type I receptor antibodies in absence of donor-specific antibodies","volume":"20","author":"Fuss","year":"2015","journal-title":"Nephrology"},{"key":"10.1111\/ajt.14053_bib20","doi-asserted-by":"crossref","first-page":"2459","DOI":"10.1111\/j.1600-6143.2009.02819.x","article-title":"Effect of antibodies on endothelium","volume":"9","author":"Zhang","year":"2009","journal-title":"Am J Transplant"},{"key":"10.1111\/ajt.14053_bib21","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1164\/rccm.201403-0442OC","article-title":"Vascular receptor autoantibodies in pulmonary arterial hypertension associated with systemic sclerosis","volume":"190","author":"Becker","year":"2014","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1111\/ajt.14053_bib22","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.bbrc.2014.07.119","article-title":"Angiotensin II enhances endothelin-1-induced vasoconstriction through upregulating endothelin type A receptor","volume":"451","author":"Lin","year":"2014","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1111\/ajt.14053_bib23","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.kint.2016.03.019","article-title":"Non-HLA antibodies against endothelial targets bridging allo- and autoimmunity","volume":"90","author":"Dragun","year":"2016","journal-title":"Kidney Int"},{"key":"10.1111\/ajt.14053_bib24","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1161\/HYPERTENSIONAHA.106.070565","article-title":"Angiotensin II type 1 receptor gene regulation: Transcriptional and posttranscriptional mechanisms","volume":"49","author":"Elton","year":"2007","journal-title":"Hypertension"},{"key":"10.1111\/ajt.14053_bib25","first-page":"7350","article-title":"Angiotensin type 1 receptor A1166C gene polymorphism is associated with endothelial dysfunction and in-stent restenosis after percutaneous coronary intervention","volume":"8","author":"Li","year":"2015","journal-title":"Int J Clin Exp Pathol"},{"key":"10.1111\/ajt.14053_bib26","doi-asserted-by":"crossref","first-page":"1948","DOI":"10.1053\/euhj.2001.2626","article-title":"A polymorphism in the endothelin-A receptor gene predicts survival in patients with idiopathic dilated cardiomyopathy","volume":"22","author":"Herrmann","year":"2001","journal-title":"Eur Heart J"},{"key":"10.1111\/ajt.14053_bib27","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1016\/j.humimm.2012.07.010","article-title":"Non-HLA-antibodies targeting Angiotensin type 1 receptor and antibody mediated rejection","volume":"73","author":"Dragun","year":"2012","journal-title":"Hum Immunol"},{"key":"10.1111\/ajt.14053_bib28","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.athoracsur.2006.07.040","article-title":"Feasibility and utility of a lung donor score: Correlation with early post-transplant outcomes","volume":"83","author":"Oto","year":"2007","journal-title":"Ann Thorac Surg"},{"key":"10.1111\/ajt.14053_bib29","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1136\/ard.2010.135772","article-title":"Involvement of functional autoantibodies against vascular receptors in systemic sclerosis","volume":"70","author":"Riemekasten","year":"2011","journal-title":"Ann Rheum Dis"}],"container-title":["American Journal of Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fajt.14053","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fajt.14053","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613522248710?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613522248710?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/ajt.14053\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:16:07Z","timestamp":1761628567000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1600613522248710"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,2]]}},"alternative-id":["S1600613522248710"],"URL":"https:\/\/doi.org\/10.1111\/ajt.14053","relation":{},"ISSN":["1600-6135"],"issn-type":[{"value":"1600-6135","type":"print"}],"subject":[],"published":{"date-parts":[[2017,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Immediate and Catastrophic Antibody-Mediated Rejection in a Lung Transplant Recipient With Anti\u2013Angiotensin II Receptor Type 1 and Anti\u2013Endothelin-1 Receptor Type A Antibodies","name":"articletitle","label":"Article Title"},{"value":"American Journal of Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1111\/ajt.14053","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2017 American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. All rights reserved. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}