{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T19:31:54Z","timestamp":1767987114848,"version":"3.49.0"},"reference-count":44,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,8,1]],"date-time":"2019-08-01T00:00:00Z","timestamp":1564617600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,11,16]],"date-time":"2022-11-16T00:00:00Z","timestamp":1668556800000},"content-version":"vor","delay-in-days":1203,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007013","name":"F. Hoffmann-La Roche","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007013","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["amjtransplant.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Transplantation"],"published-print":{"date-parts":[[2019,8]]},"DOI":"10.1111\/ajt.15296","type":"journal-article","created":{"date-parts":[[2019,2,12]],"date-time":"2019-02-12T12:46:54Z","timestamp":1549975614000},"page":"2318-2328","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"title":["Humoral response to natural influenza infection in solid organ transplant recipients"],"prefix":"10.1016","volume":"19","author":[{"given":"Cedric","family":"Hirzel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor H.","family":"Ferreira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9230-7285","authenticated-orcid":false,"given":"Arnaud G.","family":"L\u2019Huillier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katja","family":"Hoschler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisa","family":"Cordero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ajit P.","family":"Limaye","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Janet A.","family":"Englund","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gail","family":"Reid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atul","family":"Humar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deepali","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1111\/ajt.15296_bib1","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1111\/j.1399-0012.2011.01443.x","article-title":"Increased mortality of solid organ transplant recipients with H1N1 infection: a single center experience","volume":"26","author":"Gainer","year":"2012","journal-title":"Clin Transplant."},{"issue":"4","key":"10.1111\/ajt.15296_bib2","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1007\/s10096-011-1346-3","article-title":"Immunosuppressed patients with pandemic influenza A 2009 (H1N1) virus infection","volume":"31","author":"Cordero","year":"2012","journal-title":"Eur J Clin Microbiol Infect Dis."},{"issue":"5","key":"10.1111\/ajt.15296_bib3","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1111\/ctr.12726","article-title":"Antibody responses to influenza vaccine in pre- and post-lung transplant patients","volume":"30","author":"Miller","year":"2016","journal-title":"Clin Transplant."},{"issue":"1","key":"10.1111\/ajt.15296_bib4","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1053\/j.ajkd.2008.09.023","article-title":"Decreased antibody response to influenza vaccination in kidney transplant recipients: a prospective cohort study","volume":"54","author":"Birdwell","year":"2009","journal-title":"Am J Kidney Dis."},{"issue":"4","key":"10.1111\/ajt.15296_bib5","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1097\/QCO.0000000000000461","article-title":"Influenza vaccine strategies for solid organ transplant recipients","volume":"31","author":"Hirzel","year":"2018","journal-title":"Curr Opin Infect Dis."},{"key":"10.1111\/ajt.15296_bib6","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1146\/annurev.biochem.69.1.531","article-title":"Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin","volume":"69","author":"Skehel","year":"2000","journal-title":"Annu Rev Biochem."},{"issue":"5","key":"10.1111\/ajt.15296_bib7","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1586\/erv.13.35","article-title":"Immunological assessment of influenza vaccines and immune correlates of protection","volume":"12","author":"Reber","year":"2013","journal-title":"Expert Rev Vaccines."},{"issue":"4","key":"10.1111\/ajt.15296_bib8","first-page":"767","article-title":"The role of serum haemagglutination-inhibiting antibody in protection against challenge infection with influenza A2 and B viruses","volume":"70","author":"Hobson","year":"1972","journal-title":"J Hyg."},{"key":"10.1111\/ajt.15296_bib9","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/1471-2288-10-18","article-title":"Relationship between haemagglutination-inhibiting antibody titres and clinical protection against influenza: development and application of a bayesian random-effects model","volume":"10","author":"Coudeville","year":"2010","journal-title":"BMC Med Res Methodol."},{"issue":"2","key":"10.1111\/ajt.15296_bib10","doi-asserted-by":"crossref","first-page":"e00417","DOI":"10.1128\/mBio.00417-16","article-title":"Evaluation of antihemagglutinin and antineuraminidase antibodies as correlates of protection in an influenza A\/H1N1 virus healthy human challenge model","volume":"7","author":"Memoli","year":"2016","journal-title":"mBio."},{"issue":"2","key":"10.1111\/ajt.15296_bib11","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.jinf.2014.09.003","article-title":"Hemagglutination inhibiting antibodies and protection against seasonal and pandemic influenza infection","volume":"70","author":"Fox","year":"2015","journal-title":"J Infect."},{"issue":"2","key":"10.1111\/ajt.15296_bib12","doi-asserted-by":"crossref","first-page":"405","DOI":"10.4161\/hv.22908","article-title":"Correlates of protection to influenza virus, where do we go from here?","volume":"9","author":"Cox","year":"2013","journal-title":"Hum Vaccin Immunother."},{"issue":"2","key":"10.1111\/ajt.15296_bib13","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1378\/chest.12-2907","article-title":"Hyperimmune IV immunoglobulin treatment: a multicenter double-blind randomized controlled trial for patients with severe 2009 influenza A(H1N1) infection","volume":"144","author":"Hung","year":"2013","journal-title":"Chest."},{"issue":"6","key":"10.1111\/ajt.15296_bib14","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/S2213-2600(17)30174-1","article-title":"Immune plasma for the treatment of severe influenza: an open-label, multicentre, phase 2 randomised study","volume":"5","author":"Beigel","year":"2017","journal-title":"Lancet. Respir Med."},{"issue":"4","key":"10.1111\/ajt.15296_bib15","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1093\/cid\/ciq106","article-title":"Convalescent plasma treatment reduced mortality in patients with severe pandemic influenza A (H1N1) 2009 virus infection","volume":"52","author":"Hung","year":"2011","journal-title":"Clin Infect Dis."},{"issue":"1","key":"10.1111\/ajt.15296_bib16","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1111\/irv.12411","article-title":"CONSISE statement on the reporting of Seroepidemiologic Studies for influenza (ROSES-I statement): an extension of the STROBE statement","volume":"11","author":"Horby","year":"2017","journal-title":"Influenza Other Respir Viruses."},{"key":"10.1111\/ajt.15296_bib17","first-page":"1","article-title":"A five-year prospective multi-center evaluation of influenza infection in transplant recipients","volume":"000","author":"Kumar","year":"2018","journal-title":"Clin Infect Dis."},{"issue":"1","key":"10.1111\/ajt.15296_bib18","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1093\/oxfordjournals.bmb.a071545","article-title":"Determinants of immunity to influenza infection in man","volume":"35","author":"Potter","year":"1979","journal-title":"Br Med Bull."},{"issue":"9720","key":"10.1111\/ajt.15296_bib19","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1016\/S0140-6736(09)62126-7","article-title":"Incidence of 2009 pandemic influenza A H1N1 infection in England: a cross-sectional serological study","volume":"375","author":"Miller","year":"2010","journal-title":"Lancet."},{"issue":"6","key":"10.1111\/ajt.15296_bib20","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1086\/342601","article-title":"Cytomegalovirus (CMV) virus load kinetics to predict recurrent disease in solid-organ transplant patients with CMV disease","volume":"186","author":"Humar","year":"2002","journal-title":"J Infect Dis."},{"issue":"22","key":"10.1111\/ajt.15296_bib21","first-page":"414","article-title":"Prevention. Update: influenza activity - United States, 2011-12 season and composition of the 2012-13 influenza vaccine","volume":"61","year":"2012","journal-title":"MMWR Morb Mortal Wkly Rep."},{"issue":"21","key":"10.1111\/ajt.15296_bib22","first-page":"583","article-title":"Influenza activity - United States, 2014-15 season and composition of the 2015-16 influenza vaccine","volume":"64","author":"Appiah","year":"2015","journal-title":"MMWR Morb Mortal Wkly Rep."},{"issue":"21","key":"10.1111\/ajt.15296_bib23","first-page":"705","article-title":"Prevention. Update: influenza activity\u2013United States, 2010-11 season, and composition of the 2011-12 influenza vaccine","volume":"60","year":"2011","journal-title":"MMWR Morb Mortal Wkly Rep."},{"issue":"23","key":"10.1111\/ajt.15296_bib24","first-page":"473","article-title":"Prevention. Influenza activity\u2013United States, 2012-13 season and composition of the 2013-14 influenza vaccine. MMWR","volume":"62","year":"2013","journal-title":"Morb Mortal Wkly Rep."},{"issue":"22","key":"10.1111\/ajt.15296_bib25","first-page":"483","article-title":"Influenza activity - United States, 2013-14 season and composition of the 2014-15 influenza vaccines","volume":"63","author":"Epperson","year":"2014","journal-title":"MMWR Morb Mortal Wkly Rep."},{"issue":"8","key":"10.1111\/ajt.15296_bib26","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1089\/vim.2014.0010","article-title":"Humoral immune response to influenza A(H1N1)pdm2009 in patients with natural infection and in vaccine recipients in the 2009 pandemic","volume":"27","author":"Kumagai","year":"2014","journal-title":"Viral Immunol."},{"issue":"8","key":"10.1111\/ajt.15296_bib27","doi-asserted-by":"crossref","first-page":"e12474","DOI":"10.1371\/journal.pone.0012474","article-title":"Serological response in RT-PCR confirmed H1N1-2009 influenza a by hemagglutination inhibition and virus neutralization assays: an observational study","volume":"5","author":"Chen","year":"2010","journal-title":"PLoS ONE."},{"key":"10.1111\/ajt.15296_bib28","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1186\/1743-422X-8-563","article-title":"Antibody response of healthy children to pandemic A\/H1N1\/2009 influenza virus","volume":"8","author":"Esposito","year":"2011","journal-title":"Virol J."},{"issue":"1","key":"10.1111\/ajt.15296_bib29","doi-asserted-by":"crossref","first-page":"e16164","DOI":"10.1371\/journal.pone.0016164","article-title":"Serological response to the 2009 pandemic influenza A (H1N1) virus for disease diagnosis and estimating the infection rate in Thai population","volume":"6","author":"Lerdsamran","year":"2011","journal-title":"PLoS ONE."},{"issue":"5","key":"10.1111\/ajt.15296_bib30","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.vaccine.2013.11.073","article-title":"Comparable humoral response after two doses of adjuvanted influenza A\/H1N1pdm2009 vaccine or natural infection in allogeneic stem cell transplant recipients","volume":"32","author":"Dhedin","year":"2014","journal-title":"Vaccine."},{"issue":"12","key":"10.1111\/ajt.15296_bib31","doi-asserted-by":"crossref","first-page":"e28627","DOI":"10.1371\/journal.pone.0028627","article-title":"Long term immune responses to pandemic influenza A\/H1N1 infection in solid organ transplant recipients","volume":"6","author":"Baluch","year":"2011","journal-title":"PLoS ONE."},{"issue":"9","key":"10.1111\/ajt.15296_bib32","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1097\/TP.0000000000001215","article-title":"Chronic lung allograft dysfunction: a systematic review of mechanisms","volume":"100","author":"Royer","year":"2016","journal-title":"Transplantation."},{"issue":"2","key":"10.1111\/ajt.15296_bib33","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1111\/tri.12882","article-title":"Immunological diversity in phenotypes of chronic lung allograft dysfunction: a comprehensive immunohistochemical analysis","volume":"30","author":"Vandermeulen","year":"2017","journal-title":"Trans Inter."},{"issue":"5","key":"10.1111\/ajt.15296_bib34","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1128\/CVI.00555-10","article-title":"Differences in antibody responses of individuals with natural infection and those vaccinated against pandemic H1N1 2009 influenza","volume":"18","author":"Chan","year":"2011","journal-title":"Clin Vaccine Immunol."},{"issue":"3","key":"10.1111\/ajt.15296_bib35","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1097\/TP.0000000000000861","article-title":"Randomized controlled trial of adjuvanted versus nonadjuvanted influenza vaccine in kidney transplant recipients","volume":"100","author":"Kumar","year":"2016","journal-title":"Transplantation."},{"key":"10.1111\/ajt.15296_bib36","first-page":"1","article-title":"A double blind randomized trial of high dose vs. standard dose influenza vaccine in adult solid organ transplant recipients","volume":"0000","author":"Natori","year":"2017","journal-title":"Clin Infect Dis."},{"issue":"7","key":"10.1111\/ajt.15296_bib37","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1093\/cid\/ciw855","article-title":"Two doses of inactivated influenza vaccine improve immune response in solid organ transplant recipients: results of TRANSGRIPE 1-2, a randomized controlled clinical trial","volume":"64","author":"Cordero","year":"2017","journal-title":"Clin Infect Dis."},{"issue":"4","key":"10.1111\/ajt.15296_bib38","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1111\/ajt.12149","article-title":"Randomized controlled trial of high-dose intradermal versus standard-dose intramuscular influenza vaccine in organ transplant recipients","volume":"13","author":"Baluch","year":"2013","journal-title":"Am J Transplant."},{"issue":"6","key":"10.1111\/ajt.15296_bib39","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.healun.2011.01.705","article-title":"Low-dose intradermal versus intramuscular trivalent inactivated seasonal influenza vaccine in lung transplant recipients","volume":"30","author":"Manuel","year":"2011","journal-title":"J Heart Lung Transplant."},{"issue":"8","key":"10.1111\/ajt.15296_bib40","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/S1473-3099(10)70133-X","article-title":"Outcomes from pandemic influenza A H1N1 infection in recipients of solid-organ transplants: a multicentre cohort study","volume":"10","author":"Kumar","year":"2010","journal-title":"Lancet Infect Dis."},{"issue":"6","key":"10.1111\/ajt.15296_bib41","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1097\/01.ede.0000434434.52506.bc","article-title":"Commentary: lessons learned from case fatality risk estimates of 2009 pandemic influenza","volume":"24","author":"Chowell","year":"2013","journal-title":"Epidemiology."},{"issue":"6","key":"10.1111\/ajt.15296_bib42","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1097\/EDE.0b013e3182a67448","article-title":"Case fatality risk of influenza A (H1N1pdm09): a systematic review","volume":"24","author":"Wong","year":"2013","journal-title":"Epidemiology."},{"issue":"8","key":"10.1111\/ajt.15296_bib43","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1093\/infdis\/jiv195","article-title":"Antibody to influenza virus neuraminidase: an independent correlate of protection","volume":"212","author":"Monto","year":"2015","journal-title":"J Infect Dis."},{"issue":"4","key":"10.1111\/ajt.15296_bib44","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.vaccine.2014.11.054","article-title":"Virus-specific T cells as correlate of (cross-)protective immunity against influenza","volume":"33","author":"Altenburg","year":"2015","journal-title":"Vaccine."}],"container-title":["American Journal of Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fajt.15296","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajt.15296","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ajt.15296","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613522091973?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613522091973?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajt.15296","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:24:48Z","timestamp":1761629088000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1600613522091973"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8]]},"references-count":44,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2019,8]]}},"alternative-id":["S1600613522091973"],"URL":"https:\/\/doi.org\/10.1111\/ajt.15296","relation":{},"ISSN":["1600-6135"],"issn-type":[{"value":"1600-6135","type":"print"}],"subject":[],"published":{"date-parts":[[2019,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Humoral response to natural influenza infection in solid organ transplant recipients","name":"articletitle","label":"Article Title"},{"value":"American Journal of Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1111\/ajt.15296","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2019 American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. All rights reserved. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}