{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T05:41:05Z","timestamp":1780551665974,"version":"3.54.1"},"reference-count":51,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,11,14]],"date-time":"2022-11-14T00:00:00Z","timestamp":1668384000000},"content-version":"vor","delay-in-days":682,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01 AI116633"],"award-info":[{"award-number":["R01 AI116633"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["2T32 AI007472"],"award-info":[{"award-number":["2T32 AI007472"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["F31 1F311AI145193\u201001"],"award-info":[{"award-number":["F31 1F311AI145193\u201001"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["OD P51 OD011092"],"award-info":[{"award-number":["OD P51 OD011092"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006668","name":"Oregon Health and Science University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006668","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["amjtransplant.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Transplantation"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1111\/ajt.16149","type":"journal-article","created":{"date-parts":[[2020,6,17]],"date-time":"2020-06-17T11:48:45Z","timestamp":1592394525000},"page":"44-59","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["Blocking the IL-1 receptor reduces cardiac transplant ischemia and reperfusion injury and mitigates CMV-accelerated chronic rejection"],"prefix":"10.1016","volume":"21","author":[{"given":"Iris K.A.","family":"Jones","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Orloff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2977-8468","authenticated-orcid":false,"given":"Jennifer M.","family":"Burg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4871-2763","authenticated-orcid":false,"given":"Nicole N.","family":"Haese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi F.","family":"Andoh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashley","family":"Chambers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suzanne S.","family":"Fei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lina","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig N.","family":"Kreklywich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zachary J.","family":"Streblow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristian","family":"Enesthvedt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Wanderer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Baker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6828-2492","authenticated-orcid":false,"given":"Daniel N.","family":"Streblow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1111\/ajt.16149_bib1","first-page":"395","article-title":"Mechanisms of chronic cardiac allograft rejection","volume":"40","author":"Costello","year":"2013","journal-title":"Texas Hear Inst J."},{"issue":"2","key":"10.1111\/ajt.16149_bib2","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1111\/j.1399-0012.2010.01307.x","article-title":"Cardiac allograft vasculopathy: current knowledge and future direction","volume":"25","author":"Colvin-Adams","year":"2011","journal-title":"Clin Transplant."},{"issue":"2","key":"10.1111\/ajt.16149_bib3","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.anclin.2013.01.003","article-title":"A review of cardiac transplantation","volume":"31","author":"Fischer","year":"2013","journal-title":"Anesthesiol Clin."},{"issue":"1","key":"10.1111\/ajt.16149_bib4","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/1476-9255-7-27","article-title":"Anti-inflammatory treatment strategies for ischemia\/reperfusion injury in transplantation","volume":"7","author":"Lutz","year":"2010","journal-title":"J Inflamm."},{"issue":"1","key":"10.1111\/ajt.16149_bib5","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1128\/CMR.00034-08","article-title":"Immunobiology of human cytomegalovirus: from bench to bedside","volume":"22","author":"Crough","year":"2009","journal-title":"Clin Microbiol Rev."},{"issue":"1","key":"10.1111\/ajt.16149_bib6","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/j.1600-6143.2010.03365.x","article-title":"Cytomegalovirus latency promotes cardiac lymphoid neogenesis and accelerated allograft rejection in CMV Naive recipients","volume":"11","author":"Orloff","year":"2011","journal-title":"Am J Transplant."},{"issue":"3","key":"10.1111\/ajt.16149_bib7","doi-asserted-by":"crossref","first-page":"260","DOI":"10.3947\/ic.2013.45.3.260","article-title":"Cytomegalovirus infections in solid organ transplantation: a review","volume":"45","author":"Ramanan","year":"2013","journal-title":"Infect Chemother."},{"issue":"6","key":"10.1111\/ajt.16149_bib8","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1097\/00007890-199409000-00007","article-title":"Cytomegalovirus infection in transplant recipients: the role of tumor necrosis factor","volume":"58","author":"Fietze","year":"1994","journal-title":"Transplantation."},{"issue":"8","key":"10.1111\/ajt.16149_bib9","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.tcm.2014.08.004","article-title":"State of the art: cardiac transplantation","volume":"24","author":"Davis","year":"2014","journal-title":"Trends Cardiovasc Med."},{"issue":"5","key":"10.1111\/ajt.16149_bib10","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1097\/00007890-200203150-00005","article-title":"Elimination of donor-specific alloreactivity prevents cytomegalovirus-accelerated chronic rejection in rat small bowel and heart transplants","volume":"73","author":"Orloff","year":"2002","journal-title":"Transplantation."},{"issue":"3","key":"10.1111\/ajt.16149_bib11","doi-asserted-by":"crossref","first-page":"2182","DOI":"10.1128\/JVI.77.3.2182-2194.2003","article-title":"Cytomegalovirus-mediated upregulation of chemokine expression correlates with the acceleration of chronic rejection in rat heart transplants","volume":"77","author":"Streblow","year":"2003","journal-title":"J Virol."},{"issue":"21","key":"10.1111\/ajt.16149_bib12","doi-asserted-by":"crossref","first-page":"11833","DOI":"10.1128\/JVI.00452-12","article-title":"Cytomegalovirus CC chemokine promotes immune cell migration","volume":"86","author":"Vomaske","year":"2012","journal-title":"J Virol."},{"issue":"7","key":"10.1111\/ajt.16149_bib13","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1097\/00007890-199704150-00006","article-title":"Morphometric analysis of neointimal formation in murine cardiac allografts","volume":"63","author":"Armstrong","year":"1997","journal-title":"Transplantation."},{"key":"10.1111\/ajt.16149_bib14","unstructured":"Andrews S. FastQC: A quality control tool for high throughput sequence data. http:\/\/www.bioinformatics.babraham.ac.uk\/projects\/fastqc\/. Published 2010. Accessed December 15, 2016."},{"issue":"19","key":"10.1111\/ajt.16149_bib15","doi-asserted-by":"crossref","first-page":"3047","DOI":"10.1093\/bioinformatics\/btw354","article-title":"MultiQC: summarize analysis results for multiple tools and samples in a single report","volume":"32","author":"Ewels","year":"2016","journal-title":"Bioinformatics."},{"key":"10.1111\/ajt.16149_bib16","unstructured":"Bimbe B. DISCVR-Seq: labkey server extensions for management and analysis of sequencing data. https:\/\/github.com\/bbimber\/discvr-seq\/wiki. Published 2015. Accessed December 15, 2016."},{"issue":"1","key":"10.1111\/ajt.16149_bib17","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1186\/1471-2105-12-71","article-title":"LabKey Server: an open source platform for scientific data integration, analysis and collaboration","volume":"12","author":"Nelson","year":"2011","journal-title":"BMC Bioinformatics."},{"issue":"15","key":"10.1111\/ajt.16149_bib18","doi-asserted-by":"crossref","first-page":"2114","DOI":"10.1093\/bioinformatics\/btu170","article-title":"Trimmomatic: a flexible trimmer for Illumina sequence data","volume":"30","author":"Bolger","year":"2014","journal-title":"Bioinformatics."},{"issue":"1","key":"10.1111\/ajt.16149_bib19","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1093\/bioinformatics\/bts635","article-title":"STAR: ultrafast universal RNA-seq aligner","volume":"29","author":"Dobin","year":"2012","journal-title":"Bioinformatics."},{"issue":"11","key":"10.1111\/ajt.16149_bib20","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1093\/bioinformatics\/bts196","article-title":"RNA-SeQC: RNA-seq metrics for quality control and process optimization","volume":"28","author":"DeLuca","year":"2012","journal-title":"Bioinformatics."},{"key":"10.1111\/ajt.16149_bib21","unstructured":"R Core Team. R: A language and environment for statistical computing. https:\/\/www.r-project.org\/. Accessed December 15, 2016."},{"key":"10.1111\/ajt.16149_bib22","first-page":"1438","article-title":"From reads to genes to pathways: differential expression analysis of RNA-Seq experiments using Rsubread and the edgeR quasi-likelihood pipeline","volume":"5","author":"Chen","year":"2016","journal-title":"F1000 Res."},{"issue":"3","key":"10.1111\/ajt.16149_bib23","doi-asserted-by":"crossref","first-page":"R25","DOI":"10.1186\/gb-2010-11-3-r25","article-title":"A scaling normalization method for differential expression analysis of RNA-seq data","volume":"11","author":"Robinson","year":"2010","journal-title":"Genome Biol."},{"issue":"9","key":"10.1111\/ajt.16149_bib24","first-page":"561","article-title":"voom: precision weights unlock linear model analysis tools for RNA-seq read counts","volume":"22","author":"Law","year":"2014","journal-title":"Genome Biol."},{"issue":"7","key":"10.1111\/ajt.16149_bib25","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gkv007","article-title":"limma powers differential expression analyses for RNA-sequencing and microarray studies","volume":"43","author":"Ritchie","year":"2015","journal-title":"Nucleic Acids Res."},{"issue":"1","key":"10.1111\/ajt.16149_bib26","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/j.2517-6161.1995.tb02031.x","article-title":"Controlling the false discovery rate: a practical and powerful approach to multiple testing","volume":"57","author":"Benjamini","year":"1995","journal-title":"J R Stat Soc."},{"key":"10.1111\/ajt.16149_bib27","series-title":"Human cytomegaloviruses: methods and protocols","first-page":"217","article-title":"Fluorescence-based laser capture microscopy technology facilitates identification of critical in vivo cytomegalovirus transcriptional programs","author":"Kreklywich","year":"2014"},{"issue":"9","key":"10.1111\/ajt.16149_bib28","doi-asserted-by":"crossref","first-page":"2421","DOI":"10.1111\/ajt.15376","article-title":"A clinically relevant murine model unmasks a \u201ctwo-hit\u201d mechanism for reactivation and dissemination of cytomegalovirus after kidney transplant","volume":"19","author":"Zhang","year":"2019","journal-title":"Am J Transplant."},{"issue":"1","key":"10.1111\/ajt.16149_bib29","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.cardiores.2004.03.002","article-title":"Inhibition of I\u03baB phosphorylation in cardiomyocytes attenuates myocardial ischemia\/reperfusion injury","volume":"63","author":"Onai","year":"2004","journal-title":"Cardiovasc Res."},{"issue":"2","key":"10.1111\/ajt.16149_bib30","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1097\/00024382-200202000-00008","article-title":"Sesquiterpene lactone parthenolide, an inhibitor of IkB kinase complex and nuclear factor-kB, exerts beneficial effects in myocardial reperfusion injury","volume":"17","author":"Zingarelli","year":"2002","journal-title":"SHOCK."},{"issue":"3","key":"10.1111\/ajt.16149_bib31","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1111\/j.1399-0012.2010.01256.x","article-title":"Rationale and timeliness for IL-1\u03b2-targeted therapy to reduce allogeneic organ injury at procurement and to diminish risk of rejection after transplantation","volume":"24","author":"Wanderer","year":"2010","journal-title":"Clin Transplant."},{"issue":"6","key":"10.1111\/ajt.16149_bib32","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1111\/j.1432-2277.2008.00651.x","article-title":"Administration of interleukin-1 receptor antagonist ameliorates renal ischemia-reperfusion injury","volume":"21","author":"Rusai","year":"2008","journal-title":"Transpl Int."},{"issue":"1","key":"10.1111\/ajt.16149_bib33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12933-014-0158-z","article-title":"The interleukin-1 receptor antagonist anakinra improves endothelial dysfunction in streptozotocin-induced diabetic rats","volume":"13","author":"Vallejo","year":"2014","journal-title":"Cardiovasc Diabetol."},{"issue":"20","key":"10.1111\/ajt.16149_bib34","doi-asserted-by":"crossref","first-page":"2670","DOI":"10.1161\/CIRCULATIONAHA.107.740233","article-title":"Anakinra, a recombinant human interleukin-1 receptor antagonist, inhibits apoptosis in experimental acute myocardial infarction","volume":"117","author":"Abbate","year":"2008","journal-title":"Circulation."},{"issue":"8","key":"10.1111\/ajt.16149_bib35","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1038\/nrd3800","article-title":"Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases","volume":"11","author":"Dinarello","year":"2012","journal-title":"Nat Rev Drug Discov."},{"key":"10.1111\/ajt.16149_bib36","doi-asserted-by":"crossref","first-page":"370804","DOI":"10.1155\/2013\/370804","article-title":"Parthenolide is neuroprotective in rat experimental stroke model: downregulating NF- B, phospho-p38MAPK, and caspase-1 and ameliorating BBB permeability","volume":"2013","author":"Dong","year":"2013","journal-title":"Mediators Inflamm."},{"issue":"3","key":"10.1111\/ajt.16149_bib37","doi-asserted-by":"crossref","first-page":"182","DOI":"10.3109\/03009742.2014.938113","article-title":"Parthenolide inhibits pro-inflammatory cytokine production and exhibits protective effects on progression of collagen-induced arthritis in a rat model","volume":"44","author":"Liu","year":"2015","journal-title":"Scand J Rheumatol."},{"issue":"2","key":"10.1111\/ajt.16149_bib38","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1111\/j.1600-6143.2007.02062.x","article-title":"The role of angiogenic and wound repair factors during CMV-accelerated transplant vascular sclerosis in rat cardiac transplants","volume":"8","author":"Streblow","year":"2008","journal-title":"Am J Transplant."},{"issue":"1","key":"10.1111\/ajt.16149_bib39","first-page":"61","article-title":"Impact of prophylactic immediate posttransplant ganciclovir on development of transplant atherosclerosis: a post hoc analysis of a randomized, placebo-controlled study","volume":"100","author":"Valantine","year":"1999","journal-title":"Circ Am Heart Assoc."},{"issue":"18","key":"10.1111\/ajt.16149_bib40","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1056\/NEJM199204303261803","article-title":"A controlled trial of ganciclovir to prevent cytomegalovirus disease after heart transplantation","volume":"326","author":"Merigan","year":"1992","journal-title":"N Engl J Med."},{"issue":"10","key":"10.1111\/ajt.16149_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.amjcard.2009.12.059","article-title":"Interleukin-1 blockade with anakinra to prevent adverse cardiac remodeling after acute myocardial infarction (virginia commonwealth university anakinra remodeling trial [VCU-ART] pilot study)","volume":"105","author":"Abbate","year":"2010","journal-title":"Am J Cardiol."},{"issue":"9","key":"10.1111\/ajt.16149_bib42","doi-asserted-by":"crossref","first-page":"4838","DOI":"10.4049\/jimmunol.1300725","article-title":"IL-1 induces proinflammatory leukocyte infiltration and regulates fibroblast phenotype in the infarcted myocardium","volume":"191","author":"Saxena","year":"2013","journal-title":"J Immunol."},{"issue":"13","key":"10.1111\/ajt.16149_bib43","doi-asserted-by":"crossref","first-page":"3145","DOI":"10.1084\/jem.20081661","article-title":"Interleukin (IL)-1 promotes allogeneic T cell intimal infiltration and IL-17 production in a model of human artery rejection","volume":"205","author":"Rao","year":"2008","journal-title":"J Exp Med."},{"issue":"17","key":"10.1111\/ajt.16149_bib44","doi-asserted-by":"crossref","first-page":"2050","DOI":"10.1016\/j.jacc.2016.01.073","article-title":"Inflammation as a driver of adverse left ventricular remodeling after acute myocardial infarction","volume":"67","author":"Westman","year":"2016","journal-title":"J Am Coll Cardiol."},{"key":"10.1111\/ajt.16149_bib45","doi-asserted-by":"crossref","first-page":"342","DOI":"10.3389\/fphar.2017.00342","article-title":"Peri- and postoperative treatment with the interleukin-1 receptor antagonist anakinra is safe in patients undergoing renal transplantation : case series and review of the literature","volume":"8","author":"Mulders-manders","year":"2017","journal-title":"Front Pharmacol."},{"issue":"582","key":"10.1111\/ajt.16149_bib46","first-page":"1","article-title":"Cytomegalovirus infection and disease reduce 10-year cardiac allograft vasculopathy-free survival in heart transplant recipients","volume":"15","author":"Johansson","year":"2015","journal-title":"BMC Infect Dis."},{"issue":"10","key":"10.1111\/ajt.16149_bib47","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1001\/archopht.116.10.1351","article-title":"Interleukin 1 receptor antagonist suppresses allosensitization in corneal transplantation","volume":"116","author":"Yamada","year":"1998","journal-title":"Arch Ophthalmol."},{"key":"10.1111\/ajt.16149_bib48","first-page":"330","article-title":"Comparison of topical interleukin-1 vs tumor necrosis factor-alpha blockade with corticosteroid therapy on murine corneal inflammation, neovascularization, and transplant survival (an American Ophthalmological Society thesis)","volume":"105","author":"Dana","year":"2007","journal-title":"Trans Am Ophthalmol Soc."},{"issue":"10","key":"10.1111\/ajt.16149_bib49","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1097\/00007890-199705270-00022","article-title":"Topical interleukin 1 receptor antagonist promotes corneal transplant survival","volume":"63","author":"Dana","year":"1997","journal-title":"Transplantation."},{"key":"10.1111\/ajt.16149_bib50","first-page":"2614","article-title":"Cytomegalovirus infection-enhanced cardiac allograft vasculopathy is abolished by DHPG prophylaxis in the rat","volume":"95","author":"Lemstr\u00f6m","year":"1997","journal-title":"Circ Am Hear Assoc."},{"issue":"4","key":"10.1111\/ajt.16149_bib51","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1161\/01.CIR.90.4.1969","article-title":"Cytomegalovirus infection-enhanced allograft arteriosclerosis is prevented by DHPG prophylaxis in the rat","volume":"90","author":"Lemstr\u00f6m","year":"1994","journal-title":"Circulation."}],"container-title":["American Journal of Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fajt.16149","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajt.16149","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ajt.16149","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613522083174?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613522083174?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajt.16149","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:30:39Z","timestamp":1761629439000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1600613522083174"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":51,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["S1600613522083174"],"URL":"https:\/\/doi.org\/10.1111\/ajt.16149","relation":{},"ISSN":["1600-6135"],"issn-type":[{"value":"1600-6135","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Blocking the IL-1 receptor reduces cardiac transplant ischemia and reperfusion injury and mitigates CMV-accelerated chronic rejection","name":"articletitle","label":"Article Title"},{"value":"American Journal of Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1111\/ajt.16149","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2021 American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. All rights reserved. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}