{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T22:30:22Z","timestamp":1792794622574,"version":"4.5.0"},"reference-count":49,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["amjtransplant.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["American Journal of Transplantation"],"published-print":{"date-parts":[[2022,4]]},"DOI":"10.1111\/ajt.16935","type":"journal-article","created":{"date-parts":[[2021,12,25]],"date-time":"2021-12-25T13:23:19Z","timestamp":1640438599000},"page":"1213-1229","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"title":["Risk factors of invasive fungal infections in liver transplant recipients: A systematic review and meta-analysis"],"prefix":"10.1016","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9503-4830","authenticated-orcid":false,"given":"Pakpoom","family":"Phoompoung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5057-354X","authenticated-orcid":false,"given":"Sabina","family":"Herrera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2140-910X","authenticated-orcid":false,"given":"Armelle","family":"P\u00e9rez Cort\u00e9s Villalobos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1029-1812","authenticated-orcid":false,"given":"Farid","family":"Foroutan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ani","family":"Orchanian-Cheff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9216-5229","authenticated-orcid":false,"given":"Shahid","family":"Husain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1111\/ajt.16935_bib1","doi-asserted-by":"crossref","first-page":"E454","DOI":"10.1111\/ctr.12129","article-title":"Fungal infections after liver transplantation: outcomes and risk factors revisited in the MELD era","volume":"27","author":"Saliba","year":"2013","journal-title":"Clin Transplant."},{"issue":"3\u20134","key":"10.1111\/ajt.16935_bib2","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1111\/j.1399-3062.2005.00108.x","article-title":"Low-dose amphotericin for prevention of serious fungal infection following liver transplantation. Comparative Study Randomized Controlled Trial Research Support, Non-U S Gov\u2019t","volume":"7","author":"Shah","year":"2005","journal-title":"Transpl Infect Dis."},{"issue":"2","key":"10.1111\/ajt.16935_bib3","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.jiac.2015.11.005","article-title":"Epidemiology of invasive fungal infections after liver transplantation and the risk factors of late-onset invasive aspergillosis","volume":"22","author":"Nagao","year":"2016","journal-title":"J Infect Chemother."},{"issue":"2","key":"10.1111\/ajt.16935_bib4","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1002\/lt.24032","article-title":"Invasive aspergillosis in liver transplant recipients: epidemiology, clinical characteristics, treatment, and outcomes in 116 cases","volume":"21","author":"Barchiesi","year":"2015","journal-title":"Liver Transpl."},{"issue":"9","key":"10.1111\/ajt.16935_bib5","doi-asserted-by":"crossref","first-page":"e13544","DOI":"10.1111\/ctr.13544","article-title":"Invasive Aspergillosis in solid-organ transplant recipients: guidelines from the American Society of Transplantation Infectious Diseases Community of Practice","volume":"33","author":"Husain","year":"2019","journal-title":"Clin Transplant."},{"issue":"9","key":"10.1111\/ajt.16935_bib6","doi-asserted-by":"crossref","first-page":"e13623","DOI":"10.1111\/ctr.13623","article-title":"Candida infections in solid organ transplantation: guidelines from the American Society of Transplantation Infectious Diseases Community of Practice","volume":"33","author":"Aslam","year":"2019","journal-title":"Clin Transplant."},{"issue":"8","key":"10.1111\/ajt.16935_bib7","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1086\/651262","article-title":"Invasive fungal infections among organ transplant recipients: results of the transplant-associated infection surveillance network (Transnet)","volume":"50","author":"Pappas","year":"2010","journal-title":"Clin Infect Dis."},{"issue":"4","key":"10.1111\/ajt.16935_bib8","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1080\/13693780701200372","article-title":"Fungal infections in solid organ transplantation. Review","volume":"45","author":"Silveira","year":"2007","journal-title":"Med Mycol."},{"issue":"1","key":"10.1111\/ajt.16935_bib9","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1111\/ajt.12993","article-title":"Targeted versus universal antifungal prophylaxis among liver transplant recipients","volume":"15","author":"Eschenauer","year":"2015","journal-title":"Am J Transplant."},{"issue":"1","key":"10.1111\/ajt.16935_bib10","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1086\/345441","article-title":"Trends in risk profiles for and mortality associated with invasive aspergillosis among liver transplant recipients","volume":"36","author":"Singh","year":"2003","journal-title":"Clin Infect Dis."},{"issue":"11","key":"10.1111\/ajt.16935_bib11","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1053\/jlts.2002.36239","article-title":"Risk factors for invasive aspergillosis in liver transplant recipients","volume":"8","author":"Fort\u00fan","year":"2002","journal-title":"Liver Transpl."},{"issue":"4","key":"10.1111\/ajt.16935_bib12","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1002\/lt.21099","article-title":"Risk factors for invasive aspergillosis in living donor liver transplant recipients","volume":"13","author":"Osawa","year":"2007","journal-title":"Liver Transpl."},{"key":"10.1111\/ajt.16935_bib13","first-page":"719","article-title":"Developing optimal search strategies for detecting clinically sound causation studies in MEDLINE","volume":"2003","author":"Wilczynski","year":"2003","journal-title":"AMIA Annu Symp Proc."},{"issue":"3","key":"10.1111\/ajt.16935_bib14","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1620\/tjem.209.207","article-title":"Risk factors and impact of beta-D glucan on invasive fungal infection for the living donor liver transplant recipients. Review","volume":"209","author":"Kawagishi","year":"2006","journal-title":"Tohoku J Exp Med."},{"issue":"1","key":"10.1111\/ajt.16935_bib15","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1159\/000486548","article-title":"Risk analysis for invasive fungal infection after a donor liver transplantation: which patient needs potent prophylaxis?","volume":"36","author":"Utsumi","year":"2019","journal-title":"Dig Surg."},{"issue":"4","key":"10.1111\/ajt.16935_bib16","first-page":"1826","article-title":"Risk factors for deep candida infections in liver transplant recipients","volume":"22","author":"Tollemar","year":"1990","journal-title":"Transplant Proc."},{"issue":"4","key":"10.1111\/ajt.16935_bib17","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1111\/j.1399-0012.1991.tb00103.x","article-title":"Invasive Candida albicans infections in orthotopic liver graft recipients. Incidence and risk factors","volume":"5","author":"Tollemar","year":"1991","journal-title":"Clin Transplant."},{"issue":"2","key":"10.1111\/ajt.16935_bib18","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1001\/archsurg.1991.01410260033005","article-title":"Clinical spectrum of fungal infections after orthotopic liver transplantation","volume":"126","author":"Castaldo","year":"1991","journal-title":"Arch Surg."},{"issue":"3","key":"10.1111\/ajt.16935_bib19","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1093\/infdis\/170.3.644","article-title":"Risk factors for invasive fungal infections complicating orthotopic liver transplantation. Comparative study","volume":"170","author":"Collins","year":"1994","journal-title":"J Infect Dis."},{"issue":"5","key":"10.1111\/ajt.16935_bib20","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1007\/BF02114892","article-title":"Risk factors for systemic fungal infections in liver transplant recipients","volume":"14","author":"Briegel","year":"1995","journal-title":"Eur J Clin Microbiol Infect Dis."},{"key":"10.1111\/ajt.16935_bib21","first-page":"38","article-title":"Fungal infections complicating orthotopic liver transplantation","volume":"106","author":"Karchmer","year":"1995","journal-title":"Trans Am Clin Climatol Assoc."},{"issue":"4","key":"10.1111\/ajt.16935_bib22","first-page":"2323","article-title":"Prolonged graft cold ischemia: a risk factor for early bacterial and fungal infection in liver transplant recipients","volume":"27","author":"Nuno","year":"1995","journal-title":"Transplant Proc."},{"issue":"5","key":"10.1111\/ajt.16935_bib23","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1002\/hep.1840210517","article-title":"Bacterial and fungal infections after liver transplantation: an analysis of 284 patients","volume":"21","author":"Wade","year":"1995","journal-title":"Hepatology."},{"issue":"1","key":"10.1111\/ajt.16935_bib24","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1097\/00000658-199601000-00010","article-title":"Factors associated with the development of candidemia and candidemia- related death among liver transplant recipients","volume":"223","author":"Nieto-Rodriguez","year":"1996","journal-title":"Ann Surg."},{"issue":"7","key":"10.1111\/ajt.16935_bib25","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1097\/00007890-199610150-00010","article-title":"Risk factors of invasive Candida and non-Candida fungal infections after liver transplantation","volume":"62","author":"Patel","year":"1996","journal-title":"Transplantation."},{"issue":"2","key":"10.1111\/ajt.16935_bib26","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/S0002-9343(97)80021-6","article-title":"The independent role of cytomegalovirus as a risk factor for invasive fungal disease in orthotopic liver transplant recipients","volume":"103","author":"George","year":"1997","journal-title":"Am J Med."},{"issue":"3","key":"10.1111\/ajt.16935_bib27","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1097\/00007890-199902150-00010","article-title":"Human herpesvirus 6 seronegativity before transplantation predicts the occurrence of fungal infection in liver transplant recipients","volume":"67","author":"Dockrell","year":"1999","journal-title":"Transplantation."},{"issue":"12","key":"10.1111\/ajt.16935_bib28","doi-asserted-by":"crossref","first-page":"2566","DOI":"10.1097\/00007890-200006270-00016","article-title":"Human herpesvirus-6 in liver transplant recipients: role in pathogenesis of fungal infections, neurologic complications, and outcome","volume":"69","author":"Rogers","year":"2000","journal-title":"Transplantation."},{"issue":"7","key":"10.1111\/ajt.16935_bib29","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1097\/00007890-200104150-00016","article-title":"Preemptive prophylaxis with a lipid preparation of amphotericin B for invasive fungal infections in liver transplant recipients requiring renal replacement therapy","volume":"71","author":"Singh","year":"2001","journal-title":"Transplantation."},{"issue":"5","key":"10.1111\/ajt.16935_bib30","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1093\/jac\/dkg450","article-title":"Prevention of invasive fungal infections in liver transplant recipients: the role of prophylaxis with lipid formulations of amphotericin B in high-risk patients","volume":"52","author":"Fortun","year":"2003","journal-title":"J Antimicrob Chemother."},{"issue":"12","key":"10.1111\/ajt.16935_bib31","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1097\/01.TP.0000065178.93741.72","article-title":"Changes in the spectrum and risk factors for invasive candidiasis in liver transplant recipients: prospective, multicenter, case-controlled study. Clinical Trial Comparative Study Controlled Clinical Trial Multicenter Study","volume":"75","author":"Husain","year":"2003","journal-title":"Transplantation."},{"issue":"12","key":"10.1111\/ajt.16935_bib32","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1002\/lt.20827","article-title":"Association of hepatic iron overload with invasive fungal infection in liver transplant recipients","volume":"12","author":"Alexander","year":"2006","journal-title":"Liver Transpl."},{"issue":"7","key":"10.1111\/ajt.16935_bib33","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1097\/00029330-200804010-00010","article-title":"Spectrum and risk factors for invasive candidiasis and non-Candida fungal infections after liver transplantation","volume":"121","author":"Shi","year":"2008","journal-title":"Chin Med J."},{"issue":"4","key":"10.1111\/ajt.16935_bib34","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1007\/s15010-008-8124-x","article-title":"A risk profile for invasive aspergillosis in liver transplant recipients","volume":"37","author":"Rosenhagen","year":"2009","journal-title":"Infection."},{"issue":"6","key":"10.1111\/ajt.16935_bib35","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1111\/j.1751-2980.2011.00542.x","article-title":"Invasive fungal infection after liver transplantation: risk factors and significance of immune cell function monitoring","volume":"12","author":"Zhou","year":"2011","journal-title":"J Dig Dis."},{"issue":"4","key":"10.1111\/ajt.16935_bib36","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1007\/s00534-011-0423-4","article-title":"The risk factors of fungal infection in living-donor liver transplantations","volume":"19","author":"Ohkubo","year":"2012","journal-title":"J Hepatobiliary Pancreat Sci."},{"issue":"9","key":"10.1111\/ajt.16935_bib37","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1002\/lt.23467","article-title":"Invasive fungal infections following liver transplantation: incidence, risk factors, survival, and impact of fluconazole-resistant Candida parapsilosis (2003\u20132007)","volume":"18","author":"Raghuram","year":"2012","journal-title":"Liver Transpl."},{"issue":"3","key":"10.1111\/ajt.16935_bib38","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1111\/myc.12041","article-title":"Pretransplant model for end stage liver disease score predicts posttransplant incidence of fungal infections after liver transplantation","volume":"56","author":"Lichtenstern","year":"2013","journal-title":"Mycoses."},{"issue":"1","key":"10.1111\/ajt.16935_bib39","first-page":"667","article-title":"Fungal infections in liver transplant patients admitted to the intensive care unit","volume":"19","author":"Marzaban","year":"2014","journal-title":"Ann Transplant."},{"issue":"4","key":"10.1111\/ajt.16935_bib40","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1111\/tid.12560","article-title":"Antifungal prophylaxis in liver transplant recipients: one size does not fit all","volume":"18","author":"Giannella","year":"2016","journal-title":"Transpl Infect Dis."},{"issue":"2","key":"10.1111\/ajt.16935_bib41","doi-asserted-by":"crossref","first-page":"e12859","DOI":"10.1111\/tid.12859","article-title":"A simplified regimen of targeted antifungal prophylaxis in liver transplant recipients: a single-center experience","volume":"20","author":"Lavezzo","year":"2018","journal-title":"Transpl Infect Dis."},{"issue":"26","key":"10.1111\/ajt.16935_bib42","doi-asserted-by":"crossref","first-page":"e16179","DOI":"10.1097\/MD.0000000000016179","article-title":"Invasive fungal infection in liver transplant recipients in a prophylactic era: a multicenter retrospective cohort study in Korea","volume":"98","author":"Kim","year":"2019","journal-title":"Medicine (Baltimore)."},{"issue":"Suppl 1","key":"10.1111\/ajt.16935_bib43","first-page":"S30","article-title":"Systemic fungal infections in renal diseases","volume":"51","author":"Gandhi","year":"2005","journal-title":"J Postgrad Med."},{"issue":"1","key":"10.1111\/ajt.16935_bib44","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1111\/tid.12328","article-title":"Risk factors for invasive mold diseases in allogeneic hematopoietic cell transplant recipients","volume":"17","author":"Atalla","year":"2015","journal-title":"Transpl Infect Dis."},{"issue":"2","key":"10.1111\/ajt.16935_bib45","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.cmi.2017.06.016","article-title":"Multinational case-control study of risk factors for the development of late invasive pulmonary aspergillosis following kidney transplantation","volume":"24","author":"L\u00f3pez-Medrano","year":"2018","journal-title":"Clin Microbiol Infect."},{"issue":"12","key":"10.1111\/ajt.16935_bib46","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1016\/S1053-2498(01)00364-3","article-title":"Nebulized amphotericin B prophylaxis for Aspergillus infection in lung transplantation: study of risk factors","volume":"20","author":"Monforte","year":"2001","journal-title":"J Heart Lung Transplant."},{"issue":"6","key":"10.1111\/ajt.16935_bib47","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1097\/QCO.0000000000000502","article-title":"Invasive fungal disease and cytomegalovirus infection: is there an association?","volume":"31","author":"Yong","year":"2018","journal-title":"Curr Opin Infect Dis."},{"issue":"10","key":"10.1111\/ajt.16935_bib48","doi-asserted-by":"crossref","first-page":"3371","DOI":"10.1128\/IAI.00449-12","article-title":"Candida albicans and bacterial microbiota interactions in the cecum during recolonization following broad-spectrum antibiotic therapy","volume":"80","author":"Mason","year":"2012","journal-title":"Infect Immun."},{"issue":"5","key":"10.1111\/ajt.16935_bib49","doi-asserted-by":"crossref","first-page":"e12751","DOI":"10.1111\/tid.12751","article-title":"Drug-drug interactions between triazole antifungal agents used to treat invasive aspergillosis and immunosuppressants metabolized by cytochrome P450 3A4","volume":"19","author":"Groll","year":"2017","journal-title":"Transpl Infect Dis."}],"container-title":["American Journal of Transplantation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajt.16935","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/ajt.16935","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613522081795?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1600613522081795?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/ajt.16935","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:37:19Z","timestamp":1761629839000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1600613522081795"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4]]},"references-count":49,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,4]]}},"alternative-id":["S1600613522081795"],"URL":"https:\/\/doi.org\/10.1111\/ajt.16935","relation":{},"ISSN":["1600-6135"],"issn-type":[{"value":"1600-6135","type":"print"}],"subject":[],"published":{"date-parts":[[2022,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Risk factors of invasive fungal infections in liver transplant recipients: A systematic review and meta-analysis","name":"articletitle","label":"Article Title"},{"value":"American Journal of Transplantation","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1111\/ajt.16935","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2022 American Society of Transplantation & American Society of Transplant Surgeons. Published by Elsevier Inc. All rights reserved. Published by Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}