{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T18:13:38Z","timestamp":1788545618719,"version":"build-2803163510"},"reference-count":35,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,4,29]],"date-time":"2013-04-29T00:00:00Z","timestamp":1367193600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Allergy"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Patients allergic to pollen have been known to become more symptomatic during pollen season compared with the nonpollen season. However, there are few studies regarding whether higher exposure to pollen might increase the prevalence of allergic diseases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>An ecological analysis was conducted to evaluate whether pollen exposure is associated with the prevalence of allergic diseases in schoolchildren. Pollen count data of <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>apanese cedar (<jats:italic><jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>ryptomeria japonica<\/jats:italic>) and <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>apanese cypress (<jats:italic><jats:styled-content style=\"fixed-case\">C<\/jats:styled-content>hamaecyparis obtusa<\/jats:italic>), which are the major pollen allergens in <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>apan, were obtained from each prefecture. The prevalence of allergic diseases in schoolchildren in each prefecture was based on a nationwide cross\u2010sectional survey using the International Study of Asthma and Allergies in Childhood questionnaire.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>After omitting three prefectures where pollen data were not available, data of 44 prefectures were analysed. The prevalence of allergic rhinoconjunctivitis in children aged 6\u20137\u00a0years was positively associated with both cedar and cypress pollen counts (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.01, both), whereas the prevalence of allergic rhinoconjunctivitis in children aged 13\u201314\u00a0years was positively associated with only cypress pollen counts (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.003). Furthermore, the prevalence of asthma was positively associated with cedar pollen counts in 6\u2010 to 7\u2010year\u2010old children (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.003) but not cypress pollen counts in either age group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>There are ecological associations between pollen counts and the prevalence of allergic diseases in <jats:styled-content style=\"fixed-case\">J<\/jats:styled-content>apanese schoolchildren. Further studies are needed to determine whether the difference between the effects of cedar and cypress pollens is attributable to pollen counts or allergenicity.<\/jats:p><\/jats:sec>","DOI":"10.1111\/all.12164","type":"journal-article","created":{"date-parts":[[2013,4,29]],"date-time":"2013-04-29T11:39:00Z","timestamp":1367235540000},"page":"757-763","source":"Crossref","is-referenced-by-count":31,"title":["Cedar and cypress pollen counts are associated with the prevalence of allergic diseases in <scp>J<\/scp>apanese schoolchildren"],"prefix":"10.1111","volume":"68","author":[{"given":"K.","family":"Yoshida","sequence":"first","affiliation":[{"name":"Division of Allergy Tokyo Metropolitan Children's Medical Center Tokyo Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Adachi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics University of Toyama Toyama 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