{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T20:23:53Z","timestamp":1791231833827,"version":"4.1.0"},"reference-count":16,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2016,5,4]],"date-time":"2016-05-04T00:00:00Z","timestamp":1462320000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Allergy"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:label\/><jats:p>We describe the pattern of sensitisation to pet IgE components and its association with clinical symptoms. Hundred and fifty nine consecutive patients with rhinitis\/asthma sensitised to dog, cat, and horse were recruited. Specific IgE to whole extracts and to pet recombinant allergens were performed. Only 5% of patients were monosensitised to animal allergens. Specific IgE to Can f 1 was significantly associated with persistent rhinitis, Can f 2 with asthma diagnosis, Can f 3 with moderate\/severe rhinitis (M\/S\u2010R) and asthma diagnosis (AD), and Can f 5 with persistent and M\/S\u2010R. Positive IgE to Fel d 2 was significantly associated with M\/S\u2010R and AD, Equ c 1 with M\/S\u2010R and Equ c 3 with persistent rhinitis, AD and severe asthma. Sensitisation to \u22652 molecules or to pet albumins was associated with more severe respiratory symptoms. Molecular diagnosis in patients with pet allergy may also help clinicians to predict clinical symptoms and their severity.<\/jats:p><\/jats:sec>","DOI":"10.1111\/all.12917","type":"journal-article","created":{"date-parts":[[2016,4,25]],"date-time":"2016-04-25T06:53:49Z","timestamp":1461567229000},"page":"1066-1068","source":"Crossref","is-referenced-by-count":62,"title":["Clinical relevance of molecular diagnosis in pet allergy"],"prefix":"10.1111","volume":"71","author":[{"given":"S. A.","family":"Uriarte","sequence":"first","affiliation":[{"name":"Allergy department Fundacion Jimenez Diaz Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Sastre","sequence":"additional","affiliation":[{"name":"Allergy department Fundacion Jimenez Diaz Madrid Spain"},{"name":"CIBER de Enfermedades Respiratorias (CIBERES) Instituto de Salud Carlos III Universidad Autonoma de Madrid Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,5,4]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2014.08.026"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2008.01732.x"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1586\/14737159.2015.1036745"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2014.00076"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2010.06.047"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2007.04.006"},{"key":"e_1_2_10_8_1","unstructured":"Global Initiative for Asthma (GINA).Global Strategy for Asthma Management and Prevention. 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