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In this article, we reviewed the English literature from January 1930 to March 2016 using PubMed and Google Scholar searching for publications relevant to hypersensitivity to common edible seeds, namely sesame, sunflower seed, poppy seed, pumpkin seed, flaxseed, and mustard seed. Considering the worldwide consumption of those seeds, the number of published articles on the subject was relatively small and was mainly as case reports rather than large series. Allergy to sesame was more reported than to other seeds, with an estimated prevalence of 0.1\u20130.2%. In this review, we summarize the information relevant to each of the six seeds and their oils regarding the manifestations, routes of exposure, identified major allergens, and cross\u2010reactivity with other seeds or other foods. We also addressed the important role of a thorough history taking in suspecting seed allergy, the limited reliability of routine diagnostic procedures, and the importance of verification by appropriate challenge tests. At present, management is basically dietary avoidance and the use of symptomatic medications that may include epinephrine auto\u2010injectors. We did not encounter any well\u2010designed studies on immunotherapy for seed allergy, but it is hoped that such a gap be filled by the development of safe effective protocols in the near future.<\/jats:p>","DOI":"10.1111\/all.12962","type":"journal-article","created":{"date-parts":[[2016,6,22]],"date-time":"2016-06-22T21:09:18Z","timestamp":1466629758000},"page":"1405-1413","source":"Crossref","is-referenced-by-count":84,"title":["Hypersensitivities to sesame and other common edible seeds"],"prefix":"10.1111","volume":"71","author":[{"given":"A.","family":"Patel","sequence":"first","affiliation":[{"name":"Allergy &amp; Immunology Section Louisiana State University Health Shreveport LA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. L.","family":"Bahna","sequence":"additional","affiliation":[{"name":"Allergy &amp; Immunology Section Louisiana State University Health Shreveport LA 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