{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T19:26:22Z","timestamp":1789241182343,"version":"build-2803163510"},"reference-count":11,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2016,8,3]],"date-time":"2016-08-03T00:00:00Z","timestamp":1470182400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100000133","name":"Agency for Healthcare Research and Quality","doi-asserted-by":"publisher","award":["K12HS023011"],"award-info":[{"award-number":["K12HS023011"]}],"id":[{"id":"10.13039\/100000133","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001582","name":"Dermatology Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001582","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Allergy"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>The lack of standardized nomenclature for atopic dermatitis (<jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>) creates unnecessary confusion for patients, healthcare providers, and researchers. It also negatively impacts accurate communication of research in the scientific literature. We sought to determine the most commonly used terms for <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A systematic review of the <jats:styled-content style=\"fixed-case\">MEDLINE<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> EMBASE<\/jats:styled-content>, and <jats:styled-content style=\"fixed-case\">LILACS<\/jats:styled-content> (1945\u20132016) for the terms <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>, atopic eczema (<jats:styled-content style=\"fixed-case\">AE<\/jats:styled-content>), and multiple other eczematous disorders.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In <jats:styled-content style=\"fixed-case\">MEDLINE<\/jats:styled-content>, 33 060 were identified, of which 21 299 (64.4%) publications used the term \u2018<jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content>\u2019, 15 510 (46.9%) \u2018eczema\u2019, and only 2471 (7.5%) <jats:styled-content style=\"fixed-case\">AE<\/jats:styled-content>. Most of these publications used the term <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content> (82.0%) or eczema (70.8%) without additional nomenclature; only 1.2% used <jats:styled-content style=\"fixed-case\">AE<\/jats:styled-content> alone. Few publications used the terminology \u2018childhood eczema\u2019, \u2018flexural eczema\u2019, \u2018infantile eczema\u2019, \u2018atopic neurodermatitis\u2019, or \u2018Besnier's prurigo\u2019. <jats:styled-content style=\"fixed-case\">AD<\/jats:styled-content> was rarely used until the late 1970s, after which it became the most commonly used of the three terms and continuously increased until 2015. Atopic eczema decreased between 2008 and 2015. Atopic dermatitis was the most commonly used term in studies across almost all publication types, languages, and journals.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Atopic dermatitis is the most commonly used term and appears to be increasing in popularity. Given that eczema is a nonspecific term that describes the morphological appearance of several forms of dermatitis, we strongly suggest the use of a more specific term, AD, in publications, healthcare clinician training, and patient education. Support from researchers, reviewers, and editors is key to success.<\/jats:p><\/jats:sec>","DOI":"10.1111\/all.12982","type":"journal-article","created":{"date-parts":[[2016,7,8]],"date-time":"2016-07-08T14:38:01Z","timestamp":1467988681000},"page":"1480-1485","source":"Crossref","is-referenced-by-count":68,"title":["Atopic dermatitis, atopic eczema, or eczema? A systematic review, meta\u2010analysis, and recommendation for uniform use of \u2018atopic dermatitis\u2019"],"prefix":"10.1111","volume":"71","author":[{"given":"R.","family":"Kantor","sequence":"first","affiliation":[{"name":"Department of Dermatology Northwestern University Feinberg School of Medicine Chicago IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. P.","family":"Thyssen","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy Herlev\u2010Gentofte University Hospital University of Copenhagen Hellerup Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. S.","family":"Paller","sequence":"additional","affiliation":[{"name":"Departments of Dermatology and Pediatrics Northwestern University Feinberg School of Medicine Chicago IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. I.","family":"Silverberg","sequence":"additional","affiliation":[{"name":"Departments of Dermatology, Preventive Medicine and Medical Social Sciences Northwestern University Feinberg School of Medicine Chicago IL USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,8,3]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2003.09.033"},{"key":"e_1_2_8_3_1","doi-asserted-by":"crossref","first-page":"44","DOI":"10.2340\/00015555924447","article-title":"Diagnostic features of atopic dermatitis","volume":"92","author":"Hanifin J","year":"1980","journal-title":"Acta Derm Venereol (Stockh)"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1398-9995.2006.01153.x"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.13442"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2003.12.591"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2011.294"},{"key":"e_1_2_8_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2011.292"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.2010.10054.x"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2007.11.004"},{"key":"e_1_2_8_11_1","first-page":"7","article-title":"Secular change in the occurrence of atopic dermatitis","volume":"176","author":"Schultz Larsen F","year":"1992","journal-title":"Acta Derm Venereol Suppl (Stockh)"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(84)92805-8"}],"container-title":["Allergy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fall.12982","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fall.12982","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/all.12982","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,9]],"date-time":"2023-09-09T15:13:23Z","timestamp":1694272403000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/all.12982"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,3]]},"references-count":11,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2016,10]]}},"alternative-id":["10.1111\/all.12982"],"URL":"https:\/\/doi.org\/10.1111\/all.12982","archive":["Portico"],"relation":{},"ISSN":["0105-4538","1398-9995"],"issn-type":[{"value":"0105-4538","type":"print"},{"value":"1398-9995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,3]]}}}