{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T16:27:58Z","timestamp":1791995278415,"version":"4.4.0"},"reference-count":45,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2016,12,29]],"date-time":"2016-12-29T00:00:00Z","timestamp":1482969600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003793","name":"Hj\u00e4rt-Lungfonden","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003793","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr\u00e5det","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001862","name":"Svenska Forskningsr\u00e5det Formas","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001862","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004348","name":"Stockholms L\u00e4ns Landsting","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004348","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","award":["261357"],"award-info":[{"award-number":["261357"]}],"id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Allergy"],"published-print":{"date-parts":[[2017,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Exposure to moldy or damp indoor environments is associated with allergic disease in young children, but it is unclear whether the effects persist to adolescence. Our objective was to assess whether exposure to mold or dampness during infancy increases the risk of asthma, rhinitis, or IgE sensitization in children followed from birth to 16 years of age.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We collected questionnaire derived reports of mold or dampness indicators and allergic outcomes from 3798 children in a Swedish birth cohort (<jats:styled-content style=\"fixed-case\">BAMSE<\/jats:styled-content>). Sensitization was assessed from blood samples in 3293 children. Longitudinal associations between prevalent asthma, rhinitis, and IgE sensitization and mold or dampness indicators were assessed using generalized estimating equations.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Exposure to any mold or dampness indicator was associated with asthma up to 16 years of age (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 1.31; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.08\u20131.59), while exposure to mold odor (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 1.29; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.03\u20131.62) and visible mold (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 1.28; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.04\u20131.58) were associated with rhinitis. Increased risks were observed for nonallergic asthma (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 1.80; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.27\u20132.55) and rhinitis (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 1.41; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.03\u20131.93). No association was observed between mold or dampness indicators and IgE sensitization. Exposure to any mold or dampness indicator was associated with persistent asthma (<jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content> 1.73; 95% <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content> 1.20\u20132.50), but not with early\u2010transient or late\u2010onset asthma.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Exposure to mold or dampness during infancy increased the risk of asthma and rhinitis up to 16 years of age, particularly for nonallergic disease. Early exposure to mold or dampness appeared particularly associated with persistent asthma through adolescence.<\/jats:p><\/jats:sec>","DOI":"10.1111\/all.13102","type":"journal-article","created":{"date-parts":[[2016,12,7]],"date-time":"2016-12-07T16:02:49Z","timestamp":1481126569000},"page":"967-974","source":"Crossref","is-referenced-by-count":103,"title":["Mold and dampness exposure and allergic outcomes from birth to adolescence: data from the BAMSE cohort"],"prefix":"10.1111","volume":"72","author":[{"given":"J. D.","family":"Thacher","sequence":"first","affiliation":[{"name":"Institute of Environmental Medicine Karolinska Institutet Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"Gruzieva","sequence":"additional","affiliation":[{"name":"Institute of Environmental Medicine Karolinska Institutet Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Pershagen","sequence":"additional","affiliation":[{"name":"Institute of Environmental Medicine Karolinska Institutet Stockholm Sweden"},{"name":"Centre for Occupational and Environmental Medicine Stockholm County Council Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Mel\u00e9n","sequence":"additional","affiliation":[{"name":"Institute of Environmental Medicine Karolinska Institutet Stockholm Sweden"},{"name":"Sachs\u2019 Children's and Youths Hospital S\u00f6dersjukhuset Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. C.","family":"Lorentzen","sequence":"additional","affiliation":[{"name":"Centre for Occupational and Environmental Medicine Stockholm County Council Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.","family":"Kull","sequence":"additional","affiliation":[{"name":"Institute of Environmental Medicine Karolinska Institutet Stockholm Sweden"},{"name":"Sachs\u2019 Children's and Youths Hospital S\u00f6dersjukhuset Stockholm Sweden"},{"name":"Department of Clinical Science and Education S\u00f6dersjukhuset Karolinska Institutet Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Bergstr\u00f6m","sequence":"additional","affiliation":[{"name":"Institute of Environmental Medicine Karolinska Institutet Stockholm Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,12,29]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0668.2007.00474.x"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2005.057430"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0047526"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2014.07.002"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/ina.12191"},{"key":"e_1_2_9_7_1","volume-title":"WHO guidelines for indoor air quality: dampness and mould. 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