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Numerous studies have reported significant links between Th2 responses and cancer, including insights into the functions of IgE antibodies and associated effector cells in both antitumour immune surveillance and therapy. The interdisciplinary field of AllergoOncology was given Task Force status by the European Academy of Allergy and Clinical Immunology in 2014. Affiliated expert groups focus on the interface between allergic responses and cancer, applied to immune surveillance, immunomodulation and the functions of IgE\u2010mediated immune responses against cancer, to derive novel insights into more effective treatments. Coincident with rapid expansion in clinical application of cancer immunotherapies, here we review the current state\u2010of\u2010the\u2010art and future translational opportunities, as well as challenges in this relatively new field. Recent developments include improved understanding of Th2 antibodies, intratumoral innate allergy effector cells and mediators, IgE\u2010mediated tumour antigen cross\u2010presentation by dendritic cells, as well as immunotherapeutic strategies such as vaccines and recombinant antibodies, and finally, the management of allergy in daily clinical oncology. Shedding light on the crosstalk between allergic response and cancer is paving the way for new avenues of treatment.<\/jats:p>","DOI":"10.1111\/all.13119","type":"journal-article","created":{"date-parts":[[2016,12,29]],"date-time":"2016-12-29T01:26:45Z","timestamp":1482974805000},"page":"866-887","source":"Crossref","is-referenced-by-count":91,"title":["AllergoOncology \u2013 the impact of allergy in oncology:\n                    <scp>EAACI<\/scp>\n                    position paper"],"prefix":"10.1111","volume":"72","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4019-5765","authenticated-orcid":false,"given":"E.","family":"Jensen\u2010Jarolim","sequence":"first","affiliation":[{"name":"The Interuniversity Messerli Research Institute University of Veterinary Medicine Vienna Medical University of Vienna Vienna Austria"},{"name":"Institute of Pathophysiology &amp; Allergy Research Center of Pathophysiology, Infectiology &amp; Immunology Medical University Vienna Vienna Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. 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