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Systematic comparison may lead to improved recommendations for prevention and treatment in both. In this position paper, we summarize the current knowledge on immediate\u2010type food allergy vs other food adverse reactions in companion animals, and compare this to the human situation. While the prevalence of food allergy in humans has been well studied for some allergens, this remains to be investigated for animal patients, where owner\u2010reported as well as veterinarian\u2010diagnosed food adverse reactions are on the increase. The characteristics of the disease in humans vs dogs, cats, and horses are most often caused by similar, but sometimes species\u2010dependent different pathophysiological mechanisms, prompting the specific clinical symptoms, diagnoses, and treatments. Furthermore, little is known about the allergen molecules causative for type I food allergy in animals, which, like in human patients, could represent predictive biomarkers for risk evaluation. The definite diagnosis of food allergy relies\u2014as in humans\u2014on elimination diet and provocation tests. Besides allergen avoidance in daily practice, novel treatment options and tolerization strategies are underway. Taken together, numerous knowledge gaps were identified in veterinary food allergy, which need to be filled by systematic comparative studies.<\/jats:p>","DOI":"10.1111\/all.13179","type":"journal-article","created":{"date-parts":[[2017,4,10]],"date-time":"2017-04-10T14:16:26Z","timestamp":1491833786000},"page":"1643-1656","source":"Crossref","is-referenced-by-count":23,"title":["Comparing immediate\u2010type food allergy in humans and companion animals\u2014revealing unmet needs"],"prefix":"10.1111","volume":"72","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2089-6011","authenticated-orcid":false,"given":"I.","family":"Pali\u2010Sch\u00f6ll","sequence":"first","affiliation":[{"name":"Comparative Medicine The Interuniversity Messerli Research Institute of the University of Veterinary Medicine Vienna Medical University of Vienna and University of Vienna Vienna Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"De Lucia","sequence":"additional","affiliation":[{"name":"Clinica Veterinaria Privata San Marco Padova Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Jackson","sequence":"additional","affiliation":[{"name":"Dermatology Referral Services LTD Glasgow Scotland UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Janda","sequence":"additional","affiliation":[{"name":"Faculty of Science Charles University Prague Czech Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. 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