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The aim was to analyze how age affects sensitization and asthma risk. We used previous population\u2010based case\u2010control data (N=456) from Finnish adult asthma patients with one or two matched controls. Asthma was diagnosed based on a typical history of asthmatic symptoms and lung function tests. Allergic sensitization was determined by skin prick test (<jats:styled-content style=\"fixed-case\">SPT<\/jats:styled-content>) to 17 aeroallergens. Information on demographics was obtained by a questionnaire. Sensitization to more than one allergen type and the number of positive <jats:styled-content style=\"fixed-case\">SPT<\/jats:styled-content> reactions associated with younger age and asthma. Atopic subjects aged 65 and above were characterized by sensitization to only one to two allergens, with very few animal danders and without an association with asthma. Multiple sensitizations and animal dander sensitization are more common among Finnish asthmatic adults aged under 56 than among older asthmatics. Cohort studies are needed to understand timing of host\u2010environmental interactions behind this.<\/jats:p><\/jats:sec>","DOI":"10.1111\/all.13194","type":"journal-article","created":{"date-parts":[[2017,4,26]],"date-time":"2017-04-26T14:59:44Z","timestamp":1493218784000},"page":"1791-1795","source":"Crossref","is-referenced-by-count":5,"title":["Birth decade affects the sensitization pattern and asthma risk in Finnish adult population"],"prefix":"10.1111","volume":"72","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0890-6686","authenticated-orcid":false,"given":"S.","family":"Toppila\u2010Salmi","sequence":"first","affiliation":[{"name":"Haartman Institute University of Helsinki Helsinki Finland"},{"name":"Skin and Allergy Hospital University of Helsinki and Helsinki University Hospital Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Luukkainen","sequence":"additional","affiliation":[{"name":"Haartman Institute University of Helsinki Helsinki Finland"},{"name":"Department of Otolaryngology Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Lemmetyinen","sequence":"additional","affiliation":[{"name":"Haartman Institute University of Helsinki Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Karjalainen","sequence":"additional","affiliation":[{"name":"Allergy Centre Tampere University Hospital Tampere Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Huhtala","sequence":"additional","affiliation":[{"name":"Faculty of Social Sciences University of Tampere Tampere Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Renkonen","sequence":"additional","affiliation":[{"name":"Haartman Institute University of Helsinki Helsinki Finland"},{"name":"HUSLAB Helsinki University Hospital Helsinki Finland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. 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