{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T08:42:14Z","timestamp":1761986534262,"version":"3.40.5"},"reference-count":21,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2019,10,21]],"date-time":"2019-10-21T00:00:00Z","timestamp":1571616000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Allergy"],"published-print":{"date-parts":[[2020,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Background<\/jats:title><jats:p>Patients with a history of anaphylaxis are at risk of future anaphylactic reactions. Thus, secondary prevention measures are recommended for these patients to prevent or attenuate the next reaction.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Data from the Anaphylaxis Registry were analyzed to identify secondary prevention measures offered to patients who experienced anaphylaxis. Our analysis included 7788 cases from 10 European countries and Brazil.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The secondary prevention measures offered varied across the elicitors. A remarkable discrepancy was observed between prevention measures offered in specialized allergy centers (84% of patients were prescribed adrenaline autoinjectors following EAACI guidelines) and outside the centers: Here, EAACI guideline adherence was only 37%. In the multivariate analysis, the elicitor of the reaction, age of the patient, mastocytosis as comorbidity, severity of the reaction, and reimbursement\/availability of the autoinjector influence physician's decision to prescribe one.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Based on the low implementation of guidelines concerning secondary prevention measures outside of specialized allergy centers, our findings highlight the importance of these specialized centers and the requirement of better education for primary healthcare and emergency physicians.<\/jats:p><\/jats:sec>","DOI":"10.1111\/all.14069","type":"journal-article","created":{"date-parts":[[2019,10,4]],"date-time":"2019-10-04T13:44:51Z","timestamp":1570196691000},"page":"901-910","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Secondary prevention measures in anaphylaxis patients: Data from the anaphylaxis registry"],"prefix":"10.1111","volume":"75","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2770-9947","authenticated-orcid":false,"given":"Magdalena","family":"Kraft","sequence":"first","affiliation":[{"name":"Division of Allergy and Immunology Department of Dermatology Venerology and Allergology Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, corporate member of Freie Universit\u00e4t Berlin, Humboldt-Universit\u00e4t zu Berlin, and Berlin Institute of Health Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Macarena Pia","family":"Knop","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy University Hospital LMU Munich Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jean\u2010Marie","family":"Renaudin","sequence":"additional","affiliation":[{"name":"Presidency, Allergy Vigilance Network Nancy France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kathrin","family":"Scherer Hofmeier","sequence":"additional","affiliation":[{"name":"Division of Allergy Department of Dermatology University Hospital Basel University of Basel Basel Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Pf\u00f6hler","sequence":"additional","affiliation":[{"name":"Department of Dermatology The Saarland University Medical Center Homburg\/Saar Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Beatrice","family":"Bil\u00f2","sequence":"additional","affiliation":[{"name":"Allergy Unit Department of Internal Medicine University Hospital Ospedali Riuniti di Ancona Ancona Italy"},{"name":"Department of Clinical and Molecular Sciences Polytechnic University of Marche Ancona 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