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A significant number of the patients are on treatment with biologicals, and clinicians face the challenge to provide optimal care during the pandemic. Uncertainty of the potential risks for these patients is related to the fact that the exact sequence of immunological events during SARS\u2010CoV\u20102 is not known. Severe COVID\u201019 patients may experience a \u201ccytokine storm\u201d and associated organ damage characterized by an exaggerated release of pro\u2010inflammatory type 1 and type 3 cytokines. These inflammatory responses are potentially counteracted by anti\u2010inflammatory cytokines and type 2 responses. This expert\u2010based EAACI statement aims to provide guidance on the application of biologicals targeting type 2 inflammation in patients with allergic disease. Currently, there is very little evidence for an enhanced risk of patients with allergic diseases to develop severe COVID\u201019. Studies focusing on severe allergic phenotypes are lacking. At present, noninfected patients on biologicals for the treatment of asthma, atopic dermatitis, chronic rhinosinusitis with nasal polyps, or chronic spontaneous urticaria should continue their biologicals targeting type 2 inflammation via self\u2010application. In case of an active SARS\u2010CoV\u20102 infection, biological treatment needs to be stopped until clinical recovery and SARS\u2010CoV\u20102 negativity is established and treatment with biologicals should be re\u2010initiated. Maintenance of add\u2010on therapy and a constant assessment of disease control, apart from acute management, are demanded.<\/jats:p>","DOI":"10.1111\/all.14407","type":"journal-article","created":{"date-parts":[[2020,6,5]],"date-time":"2020-06-05T08:40:41Z","timestamp":1591346441000},"page":"2764-2774","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":74,"title":["Considerations on biologicals for patients with allergic disease in times of the COVID\u201019 pandemic: An EAACI statement"],"prefix":"10.1111","volume":"75","author":[{"given":"Alessandra","family":"Vultaggio","sequence":"first","affiliation":[{"name":"Immunoallergology Unit Careggi University Hospital Florence Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7994-364X","authenticated-orcid":false,"given":"Ioana","family":"Agache","sequence":"additional","affiliation":[{"name":"Transylvania University Brasov 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