{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T19:18:19Z","timestamp":1771269499116,"version":"3.50.1"},"reference-count":52,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2021,9,30]],"date-time":"2021-09-30T00:00:00Z","timestamp":1632960000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Allergy"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Older adults, especially men and\/or those with diabetes, hypertension, and\/or obesity, are prone to severe COVID\u201019. In some countries, older adults, particularly those residing in nursing homes, have been prioritized to receive COVID\u201019 vaccines due to high risk of death. In very rare instances, the COVID\u201019 vaccines can induce anaphylaxis, and the management of anaphylaxis in older people should be considered carefully. An ARIA\u2010EAACI\u2010EuGMS (Allergic Rhinitis and its Impact on Asthma, European Academy of Allergy and Clinical Immunology, and European Geriatric Medicine Society) Working Group has proposed some recommendations for older adults receiving the COVID\u201019 vaccines. Anaphylaxis to COVID\u201019 vaccines is extremely rare (from 1 per 100,000 to 5 per million injections). Symptoms are similar in younger and older adults but they tend to be more severe in the older patients. Adrenaline is the mainstay treatment and should be readily available. A flowchart is proposed to manage anaphylaxis in the older patients.<\/jats:p>","DOI":"10.1111\/all.14838","type":"journal-article","created":{"date-parts":[[2021,4,3]],"date-time":"2021-04-03T02:20:55Z","timestamp":1617416455000},"page":"2952-2964","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Management of anaphylaxis due to COVID\u201019 vaccines in the elderly"],"prefix":"10.1111","volume":"76","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4061-4766","authenticated-orcid":false,"given":"Jean","family":"Bousquet","sequence":"first","affiliation":[{"name":"Department of Dermatology and Allergy Comprehensive Allergy Center Charit\u00e9 Universit\u00e4tsmedizin Berlin Humboldt\u2010Universit\u00e4t zu Berlin Berlin Institute of Health  Berlin Germany"},{"name":"University Hospital Montpellier  France"},{"name":"MACVIA\u2010France  Montpellier France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7994-364X","authenticated-orcid":false,"given":"Ioana","family":"Agache","sequence":"additional","affiliation":[{"name":"Faculty of Medicine Transylvania University  Brasov Romania"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hubert","family":"Blain","sequence":"additional","affiliation":[{"name":"Department of Geriatrics Montpellier University Hospital  Montpellier France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marek","family":"Jutel","sequence":"additional","affiliation":[{"name":"Department of Clinical Immunology Wroc\u0142aw Medical University  Wroclaw Poland"},{"name":"ALL\u2010MED Medical Research Institute  Wroc\u0142aw Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Teresa","family":"Ventura","sequence":"additional","affiliation":[{"name":"University of Bari Medical School Unit of Geriatric Immunoallergology  Bari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3449-1245","authenticated-orcid":false,"given":"Margitta","family":"Worm","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Allergy Comprehensive Allergy Center Charit\u00e9 Universit\u00e4tsmedizin Berlin Humboldt\u2010Universit\u00e4t zu Berlin Berlin Institute of Health  Berlin Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Del Giacco","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences and Public Health Unit of Allergy and Clinical Immunology University Hospital \"Duilio Casula\" University of Cagliari  Cagliari Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Athanasios","family":"Benetos","sequence":"additional","affiliation":[{"name":"Department of Geriatrics CHRU de Nancy and Inserm DCAC Universit\u00e9 de Lorraine  Nancy France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beatrice Maria","family":"Bilo","sequence":"additional","affiliation":[{"name":"Allergy Unit Department of Clinical and Molecular Sciences Universit\u00e0 Politecnica delle Marche  Ancona Italy"},{"name":"Department of Internal Medicine University Hospital Ospedali Riuniti di Ancona  Ancona Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wienczyslawa","family":"Czarlewski","sequence":"additional","affiliation":[{"name":"Medical Consulting Czarlewski  Levallois France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amir Hamzah","family":"Abdul Latiff","sequence":"additional","affiliation":[{"name":"Department of Pediatrics Allergy &amp; 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