{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T00:06:43Z","timestamp":1788998803471,"version":"build-2803163510"},"reference-count":29,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,11,20]],"date-time":"2022-11-20T00:00:00Z","timestamp":1668902400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Allergy"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Introduction<\/jats:title><jats:p>Data from mHealth apps can provide valuable information on rhinitis control and treatment patterns. However, in MASK\u2010air\u00ae, these data have only been analyzed cross\u2010sectionally, without considering the changes of symptoms over time. We analyzed data from MASK\u2010air\u00ae longitudinally, clustering weeks according to reported rhinitis symptoms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>We analyzed MASK\u2010air\u00ae data, assessing the weeks for which patients had answered a rhinitis daily questionnaire on all 7\u2009days. We firstly used k\u2010means clustering algorithms for longitudinal data to define clusters of weeks according to the trajectories of reported daily rhinitis symptoms. Clustering was applied separately for weeks when medication was reported or not. We compared obtained clusters on symptoms and rhinitis medication patterns. We then used the latent class mixture model to assess the robustness of results.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>We analyzed 113,239\u2009days (16,177 complete weeks) from 2590 patients (mean age\u2009\u00b1\u2009SD\u00a0=\u00a039.1\u2009\u00b1\u200913.7\u2009years). The first clustering algorithm identified ten clusters among weeks with medication use: seven with low variability in rhinitis control during the week and three with highly\u2010variable control. Clusters with poorly\u2010controlled rhinitis displayed a higher frequency of rhinitis co\u2010medication, a more frequent change of medication schemes and more pronounced seasonal patterns. Six clusters were identified in weeks when no rhinitis medication was used, displaying similar control patterns. The second clustering method provided similar results. Moreover, patients displayed consistent levels of rhinitis control, reporting several weeks with similar levels of control.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>We identified 16 patterns of weekly rhinitis control. Co\u2010medication and medication change schemes were common in uncontrolled weeks, reinforcing the hypothesis that patients treat themselves according to their symptoms.<\/jats:p><\/jats:sec>","DOI":"10.1111\/all.15574","type":"journal-article","created":{"date-parts":[[2022,11,3]],"date-time":"2022-11-03T08:24:54Z","timestamp":1667463894000},"page":"968-983","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["Consistent trajectories of rhinitis control and treatment in 16,177\u2009weeks: The <scp>MASK<\/scp>\u2010air\u00ae longitudinal study"],"prefix":"10.1111","volume":"78","author":[{"given":"Bernardo","family":"Sousa\u2010Pinto","sequence":"first","affiliation":[{"name":"MEDCIDS \u2010 Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine University of Porto  Porto Portugal"},{"name":"CINTESIS \u2013 Center for Health Technology and Services Research University of Porto  Porto Portugal"},{"name":"RISE \u2013 Health Research Network University of Porto  Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holger J.","family":"Sch\u00fcnemann","sequence":"additional","affiliation":[{"name":"Department of Health Research Methods, Evidence, and Impact &amp; Department of Medicine McMaster University  Hamilton Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"S\u00e1\u2010Sousa","sequence":"additional","affiliation":[{"name":"MEDCIDS \u2010 Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine University of Porto  Porto Portugal"},{"name":"CINTESIS \u2013 Center for Health Technology and Services Research University of Porto  Porto Portugal"},{"name":"RISE \u2013 Health Research Network University of Porto  Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1834-3055","authenticated-orcid":false,"given":"Rafael Jos\u00e9","family":"Vieira","sequence":"additional","affiliation":[{"name":"MEDCIDS \u2010 Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine University of Porto  Porto Portugal"},{"name":"CINTESIS \u2013 Center for Health Technology and Services Research University of Porto  Porto Portugal"},{"name":"RISE \u2013 Health Research Network University of Porto  Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0233-830X","authenticated-orcid":false,"given":"Rita","family":"Amaral","sequence":"additional","affiliation":[{"name":"MEDCIDS \u2010 Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine University of Porto  Porto Portugal"},{"name":"CINTESIS \u2013 Center for Health Technology and Services Research University of Porto  Porto Portugal"},{"name":"RISE \u2013 Health Research Network University of Porto  Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep M.","family":"Anto","sequence":"additional","affiliation":[{"name":"ISGlobal, Barcelona Institute for Global Health  Barcelona Spain"},{"name":"IMIM (Hospital del Mar Medical Research Institute)  Barcelona Spain"},{"name":"Universitat Pompeu Fabra (UPF)  Barcelona Spain"},{"name":"CIBER Epidemiolog\u00eda y Salud P\u00fablica (CIBERESP)  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2455-0192","authenticated-orcid":false,"given":"Ludger","family":"Klimek","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery Universit\u00e4tsmedizin Mainz  Mainz Germany"},{"name":"Center for Rhinology and Allergology  Wiesbaden Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wienczyslawa","family":"Czarlewski","sequence":"additional","affiliation":[{"name":"Medical Consulting Czarlewski  Levallois France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joaquim","family":"Mullol","sequence":"additional","affiliation":[{"name":"Rhinology Unit &amp; Smell Clinic, ENT Department, Hospital Cl\u00ednic, Clinical &amp; Experimental Respiratory Immunoallergy, IDIBAPS, CIBERES University of Barcelona  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4374-9639","authenticated-orcid":false,"given":"Oliver","family":"Pfaar","sequence":"additional","affiliation":[{"name":"Section of Rhinology and Allergy, Department of Otorhinolaryngology, Head and Neck Surgery University Hospital Marburg, Philipps\u2010Universit\u00e4t Marburg  Marburg Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna","family":"Bedbrook","sequence":"additional","affiliation":[{"name":"ARIA  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luisa","family":"Brussino","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences, Allergy and Clinical Immunology Unit University of Torino &amp; Mauriziano Hospital  Torino Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Violeta","family":"Kvedariene","sequence":"additional","affiliation":[{"name":"Institute of Biomedical Sciences, Department of Pathology, Faculty of Medicine Vilnius University  Vilnius Lithuania"},{"name":"Institute of Clinical medicine, Clinic of Chest diseases and Allergology, Faculty of Medicine Vilnius University  Vilnius Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D\u00e9sir\u00e9e E.","family":"Larenas\u2010Linnemann","sequence":"additional","affiliation":[{"name":"Center of Excellence in Asthma and Allergy M\u00e9dica Sur Clinical Foundation and Hospital  M\u00e9xico City Mexico"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshitaka","family":"Okamoto","sequence":"additional","affiliation":[{"name":"Chiba University Hospital and Chiba Rosai Hospital  Chiba Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Teresa","family":"Ventura","sequence":"additional","affiliation":[{"name":"Unit of Geriatric Immunoallergology University of Bari Medical School  Bari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7994-364X","authenticated-orcid":false,"given":"Ioana","family":"Agache","sequence":"additional","affiliation":[{"name":"Transylvania University Brasov  Brasov Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ignacio J.","family":"Ansotegui","sequence":"additional","affiliation":[{"name":"Department of Allergy and Immunology Hospital Quironsalud Bizkaia  Bilbao Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0306-9922","authenticated-orcid":false,"given":"Karl C.","family":"Bergmann","sequence":"additional","affiliation":[{"name":"Institute of Allergology, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"},{"name":"Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sinthia","family":"Bosnic\u2010Anticevich","sequence":"additional","affiliation":[{"name":"Quality Use of Respiratory Medicine Group, Woolcock Institute of Medical Research The University of Sydney and Sydney Local Health District  Sydney New South Wales Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. Walter","family":"Canonica","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences Humanitas University  Pieve Emanuele Italy"},{"name":"Personalized Medicine, Asthma and Allergy, Humanitas Clinical and Research Center IRCCS  Rozzano Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Cardona","sequence":"additional","affiliation":[{"name":"Allergy Section, Department of Internal Medicine Hospital Vall d'Hebron &amp; ARADyAL research network  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4129-133X","authenticated-orcid":false,"given":"Pedro","family":"Carreiro\u2010Martins","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Imunoalergologia, Hospital de Dona Estef\u00e2nia, Centro Hospitalar Universit\u00e1rio de Lisboa Central  Lisbon Portugal"},{"name":"NOVA Medical School\/Comprehensive Health Research Centre (CHRC)  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Casale","sequence":"additional","affiliation":[{"name":"Division of Allergy\/immunology University of South Florida  Tampa Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0658-2449","authenticated-orcid":false,"given":"Lorenzo","family":"Cecchi","sequence":"additional","affiliation":[{"name":"SOS Allergology and Clinical Immunology, USL Toscana Centro  Prato Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomas","family":"Chivato","sequence":"additional","affiliation":[{"name":"School of Medicine, University CEU San Pablo  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Derek K.","family":"Chu","sequence":"additional","affiliation":[{"name":"Department of Health Research Methods, Evidence, and Impact &amp; Department of Medicine McMaster University  Hamilton Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3934-5092","authenticated-orcid":false,"given":"Cemal","family":"Cingi","sequence":"additional","affiliation":[{"name":"ENT Department, Medical Faculty Eskisehir Osmangazi University  Eskisehir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"El\u00edsio M.","family":"Costa","sequence":"additional","affiliation":[{"name":"UCIBIO, REQUINTE, Faculty of Pharmacy and Competence Center on Active and Healthy Ageing of University of Porto (Porto4Ageing)  Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7403-3871","authenticated-orcid":false,"given":"Alvaro A.","family":"Cruz","sequence":"additional","affiliation":[{"name":"Funda\u00e7ao ProAR, Federal University of Bahia and GARD\/WHO Planning Group  Salvador Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4517-1749","authenticated-orcid":false,"given":"Stefano","family":"Del Giacco","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences and Public Health and Unit of Allergy and Clinical Immunology University Hospital \"Duilio Casula\", University of Cagliari  Cagliari Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Devillier","sequence":"additional","affiliation":[{"name":"VIM Suresnes, UMR 0892, P\u00f4le des Maladies des Voies Respiratoires, H\u00f4pital Foch Universit\u00e9 Paris\u2010Saclay  Suresnes France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrik","family":"Eklund","sequence":"additional","affiliation":[{"name":"Department of Computing Science Ume\u00e5 University  Ume\u00e5 Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4852-229X","authenticated-orcid":false,"given":"Wytske J.","family":"Fokkens","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Amsterdam University Medical Centres, location AMC  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bilun","family":"Gemicioglu","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Diseases, Cerrahpasa Faculty of Medicine Istanbul University\u2010Cerrahpasa  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4757-2156","authenticated-orcid":false,"given":"Tari","family":"Haahtela","sequence":"additional","affiliation":[{"name":"Skin and Allergy Hospital Helsinki University Hospital, University of Helsinki  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan Carlos","family":"Ivancevich","sequence":"additional","affiliation":[{"name":"Servicio de Alergia e Immunologia Clinica Santa Isabel  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhanat","family":"Ispayeva","sequence":"additional","affiliation":[{"name":"Kazakhstan Association of Allergology and Clinical Immunology, Department of Allergology and Clinical Immunology of the Kazakh National Medical University  Almaty Kazakhstan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marek","family":"Jutel","sequence":"additional","affiliation":[{"name":"Department of Clinical Immunology Wroc\u0142aw Medical University, and ALL\u2010MED Medical Research Institute  Wroclaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piotr","family":"Kuna","sequence":"additional","affiliation":[{"name":"Division of Internal Medicine, Asthma and Allergy Barlicki University Hospital, Medical University of Lodz  Lodz Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Igor","family":"Kaidashev","sequence":"additional","affiliation":[{"name":"Poltava State Medical University  Poltava Ukraine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4961-9640","authenticated-orcid":false,"given":"Musa","family":"Khaitov","sequence":"additional","affiliation":[{"name":"Laboratory of Molecular immunology, National Research Center Institute of Immunology, Federal Medicobiological Agency  Moscow Russian Federation"},{"name":"Pirogov Russian National Research Medical University  Moscow Russian Federation"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helga","family":"Kraxner","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery Semmelweis University  Budapest Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Laune","sequence":"additional","affiliation":[{"name":"KYomed INNOV  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Lipworth","sequence":"additional","affiliation":[{"name":"Scottish Centre for Respiratory Research, Cardiovascular &amp; Diabetes Medicine, Medical Research Institute, Ninewells Hospital University of Dundee  Dundee UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renaud","family":"Louis","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Medicine, CHU Li\u00e8ge and GIGA I3 research group University of Li\u00e8ge  Liege Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Makris","sequence":"additional","affiliation":[{"name":"Allergy Unit \"D Kalogeromitros\", 2nd Department of Dermatology and Venereology \"Attikon\" University Hospital, National &amp; Kapodistrian University of Athens  Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riccardo","family":"Monti","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular and Thoracic Sciences, Fondazione Policlinico Universitario A Gemelli IRCCS Universit\u00e0 Cattolica del Sacro Cuore  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1837-2980","authenticated-orcid":false,"given":"Mario","family":"Morais\u2010Almeida","sequence":"additional","affiliation":[{"name":"Allergy Center, CUF Descobertas Hospital  Lisbon Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralph","family":"M\u00f6sges","sequence":"additional","affiliation":[{"name":"IMSB, Medical Faculty University at Cologne, and ClinCompetence Cologne GmbH  Cologne Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marek","family":"Niedoszytko","sequence":"additional","affiliation":[{"name":"Department of Allergology Medical University of Gda\u0144sk  Gdansk Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4448-3468","authenticated-orcid":false,"given":"Nikolaos G.","family":"Papadopoulos","sequence":"additional","affiliation":[{"name":"Allergy Department, 2nd Pediatric Clinic University of Athens  Athens Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5640-6446","authenticated-orcid":false,"given":"Vincenzo","family":"Patella","sequence":"additional","affiliation":[{"name":"Division of Allergy and Clinical Immunology, Department of Medicine \"Santa Maria della Speranza\" Hospital, Battipaglia and Agency of Health ASL  Salerno Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nh\u00e2n","family":"Pham\u2010Thi","sequence":"additional","affiliation":[{"name":"Ecole Polytechnique Palaiseau IRBA (Institut de Recherche bio\u2010M\u00e9dicale des Arm\u00e9es)  Bretigny France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frederico S.","family":"Regateiro","sequence":"additional","affiliation":[{"name":"Allergy and Clinical Immunology Unit Centro Hospitalar e Universit\u00e1rio de Coimbra  Coimbra Portugal"},{"name":"Faculty of Medicine, Institute of Immunology University of Coimbra  Coimbra Portugal"},{"name":"Faculty of Medicine, Coimbra Institute for Clinical and Biomedical Research (iCBR) University of Coimbra  Coimbra Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sietze","family":"Reitsma","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology Amsterdam University Medical Centres, AMC  Amsterdam The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5365-9568","authenticated-orcid":false,"given":"Philip W.","family":"Rouadi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2010Head and Neck Surgery Eye and Ear University Hospital  Beirut Lebanon"},{"name":"Department of Otorhinolaryngology\u2010Head and Neck Surgery Dar Al Shifa Hospital  Salmiya Kuwait"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Boleslaw","family":"Samolinski","sequence":"additional","affiliation":[{"name":"Department of Prevention of Environmental Hazards, Allergology and Immunology Medical University of Warsaw  Warsaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aziz","family":"Sheikh","sequence":"additional","affiliation":[{"name":"Usher Institute, The University of Edinburgh  Edinburgh UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milan","family":"Sova","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine and Tuberculosis University Hospital  Brno Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"Todo\u2010Bom","sequence":"additional","affiliation":[{"name":"Imunoalergologia, Centro Hospitalar Universit\u00e1rio de Coimbra, Faculty of Medicine University of Coimbra  Coimbra Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Taborda\u2010Barata","sequence":"additional","affiliation":[{"name":"CICS\u2010UBI Health Sciences Research Centre University of Beira Interior  Covilh\u00e3 Portugal"},{"name":"UBIAir \u2010 Clinical &amp; Experimental Lung Centre University of Beira Interior  Covilh\u00e3 Portugal"},{"name":"Department of Immunoallergology Cova da Beira University Hospital Centre  Covilh\u00e3 Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0890-6686","authenticated-orcid":false,"given":"Sanna","family":"Toppila\u2010Salmi","sequence":"additional","affiliation":[{"name":"Skin and Allergy Hospital Helsinki University Hospital, University of Helsinki  Helsinki Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joaquin","family":"Sastre","sequence":"additional","affiliation":[{"name":"Fundacion Jimenez Diaz, CIBERES, Faculty of Medicine Autonoma University of Madrid  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ioanna","family":"Tsiligianni","sequence":"additional","affiliation":[{"name":"Health Planning Unit, Department of Social Medicine, Faculty of Medicine University of Crete  Iraklio Greece"},{"name":"International Primary Care Respiratory Group IPCRG  Aberdeen UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arunas","family":"Valiulis","sequence":"additional","affiliation":[{"name":"Institute of Clinical Medicine and Institute of Health Sciences Vilnius and Medical Faculty of Vilnius University  Vilnius Lithuania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4608-3310","authenticated-orcid":false,"given":"Olivier","family":"Vandenplas","sequence":"additional","affiliation":[{"name":"Department of Chest Medicine Centre Hospitalier Universitaire UCL, Namur, and Universit\u00e9 Catholique de Louvain  Yvoir Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dana","family":"Wallace","sequence":"additional","affiliation":[{"name":"Nova Southeastern University  Fort Lauderdale Florida USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan","family":"Waserman","sequence":"additional","affiliation":[{"name":"Department of Medicine, Clinical Immunology and Allergy McMaster University  Hamilton Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arzu","family":"Yorgancioglu","sequence":"additional","affiliation":[{"name":"Department of Pulmonary Diseases Celal Bayar University, Faculty of Medicine  Manisa Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mihaela","family":"Zidarn","sequence":"additional","affiliation":[{"name":"University Clinic of Respiratory and Allergic Diseases  Golnick Slovenia"},{"name":"Faculty of Medicine University of Ljubljana  Ljubljana Slovenia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1466-8875","authenticated-orcid":false,"given":"Torsten","family":"Zuberbier","sequence":"additional","affiliation":[{"name":"Institute of Allergology, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"},{"name":"Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joao A.","family":"Fonseca","sequence":"additional","affiliation":[{"name":"MEDCIDS \u2010 Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine University of Porto  Porto Portugal"},{"name":"CINTESIS \u2013 Center for Health Technology and Services Research University of Porto  Porto Portugal"},{"name":"RISE \u2013 Health Research Network University of Porto  Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4061-4766","authenticated-orcid":false,"given":"Jean","family":"Bousquet","sequence":"additional","affiliation":[{"name":"Institute of Allergology, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"},{"name":"Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology  Berlin Germany"},{"name":"University Hospital Montpellier  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,11,20]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13601-019-0252-0"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01023-2019"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.13177"},{"key":"e_1_2_10_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/clt2.12062"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.13448"},{"key":"e_1_2_10_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.13406"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/cea.13333"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2019.01.053"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13601-020-00342-x"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2019.06.049"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11749-009-0138-x"},{"key":"e_1_2_10_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/2193-1801-2-222"},{"key":"e_1_2_10_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmr.2019.08.003"},{"key":"e_1_2_10_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40413-018-0194-3"},{"key":"e_1_2_10_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.13218"},{"key":"e_1_2_10_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmpb.2011.05.008"},{"key":"e_1_2_10_18_1","doi-asserted-by":"publisher","DOI":"10.4324\/9780203771587"},{"key":"e_1_2_10_19_1","doi-asserted-by":"publisher","DOI":"10.1002\/jad.12042"},{"key":"e_1_2_10_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/9781119942986"},{"key":"e_1_2_10_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.g7731"},{"key":"e_1_2_10_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.waojou.2022.100660"},{"key":"e_1_2_10_23_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291720005127"},{"key":"e_1_2_10_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.14422"},{"key":"e_1_2_10_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/clt2.12062"},{"key":"e_1_2_10_26_1","doi-asserted-by":"publisher","DOI":"10.1159\/000332924"},{"issue":"6","key":"e_1_2_10_27_1","first-page":"216","article-title":"Pilot study on the short\u2010term prediction of symptoms in children with hay fever monitored with e\u2010health technology","volume":"46","author":"Costa C","year":"2014","journal-title":"Eur Ann Allergy Clin Immunol"},{"key":"e_1_2_10_28_1","doi-asserted-by":"publisher","DOI":"10.2196\/16642"},{"key":"e_1_2_10_29_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0242197"},{"key":"e_1_2_10_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/all.15199"}],"container-title":["Allergy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/all.15574","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/all.15574","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/all.15574","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T12:20:38Z","timestamp":1692706838000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/all.15574"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,20]]},"references-count":29,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,4]]}},"alternative-id":["10.1111\/all.15574"],"URL":"https:\/\/doi.org\/10.1111\/all.15574","archive":["Portico"],"relation":{},"ISSN":["0105-4538","1398-9995"],"issn-type":[{"value":"0105-4538","type":"print"},{"value":"1398-9995","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,20]]},"assertion":[{"value":"2022-07-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-10-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-11-20","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}