{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T14:42:56Z","timestamp":1787236976160,"version":"build-2736575974"},"reference-count":108,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2023,6,30]],"date-time":"2023-06-30T00:00:00Z","timestamp":1688083200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Allergy"],"published-print":{"date-parts":[[2023,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Biomarkers for the diagnosis, treatment and follow\u2010up of patients with rhinitis and\/or asthma are urgently needed. Although some biologic biomarkers exist in specialist care for asthma, they cannot be largely used in primary care. There are no validated biomarkers in rhinitis or allergen immunotherapy (AIT) that can be used in clinical practice. The digital transformation of health and health care (including mHealth) places the patient at the center of the health system and is likely to optimize the practice of allergy. Allergic Rhinitis and its Impact on Asthma (ARIA) and EAACI (European Academy of Allergy and Clinical Immunology) developed a Task Force aimed at proposing patient\u2010reported outcome measures (PROMs) as digital biomarkers that can be easily used for different purposes in rhinitis and asthma. It first defined control digital biomarkers that should make a bridge between clinical practice, randomized controlled trials, observational real\u2010life studies and allergen challenges. Using the MASK\u2010air app as a model, a daily electronic combined symptom\u2010medication score for allergic diseases (CSMS) or for asthma (e\u2010DASTHMA), combined with a monthly control questionnaire, was embedded in a strategy similar to the diabetes approach for disease control. To mimic real\u2010life, it secondly proposed quality\u2010of\u2010life digital biomarkers including daily EQ\u20105D visual analogue scales and the bi\u2010weekly RhinAsthma Patient Perspective (RAAP). The potential implications for the management of allergic respiratory diseases were proposed.<\/jats:p>","DOI":"10.1111\/all.15740","type":"journal-article","created":{"date-parts":[[2023,4,12]],"date-time":"2023-04-12T02:39:56Z","timestamp":1681267196000},"page":"1758-1776","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":33,"title":["Patient\u2010centered digital biomarkers for allergic respiratory diseases and asthma: The\n                    <scp>ARIA\u2010EAACI<\/scp>\n                    approach \u2013 ARIA\u2010EAACI Task Force Report"],"prefix":"10.1111","volume":"78","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4061-4766","authenticated-orcid":false,"given":"Jean","family":"Bousquet","sequence":"first","affiliation":[{"name":"Institute of Allergology, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin Germany"},{"name":"University Hospital Montpellier  Montpellier France"},{"name":"Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Allergology and Immunology  Berlin Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3425-3463","authenticated-orcid":false,"given":"Mohamed H.","family":"Shamji","sequence":"additional","affiliation":[{"name":"National Heart and Lung Institute (NHLI), Imperial College London  London UK"},{"name":"NIHR Imperial Biomedical Research Centre  London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep M.","family":"Anto","sequence":"additional","affiliation":[{"name":"ISGlobal, Barcelona Institute for Global Health  Barcelona Spain"},{"name":"Universitat Pompeu Fabra (UPF)  Barcelona Spain"},{"name":"CIBER Epidemiolog\u00eda y Salud P\u00fablica (CIBERESP)  Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holger J.","family":"Sch\u00fcnemann","sequence":"additional","affiliation":[{"name":"Department of Health Research Methods, Evidence, and Impact, Department of Medicine McMaster University  Hamilton Ontario Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. Walter","family":"Canonica","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences Humanitas University  Milan Italy"},{"name":"Personalized Medicine, Asthma &amp; Allergy IRCCS Humanitas Research Center  Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marek","family":"Jutel","sequence":"additional","affiliation":[{"name":"Department of Clinical Immunology Wroc\u0142aw Medical University  Wroclaw Poland"},{"name":"ALL\u2010MED Medical Research Institute  Wroclaw Poland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4517-1749","authenticated-orcid":false,"given":"Stefano","family":"Del\u00a0Giacco","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences and Public Health and Unit of Allergy and Clinical Immunology University Hospital \"Duilio Casula,\" University of Cagliari  Cagliari 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