{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T22:33:31Z","timestamp":1790721211566,"version":"4.1.0"},"reference-count":34,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2023,12,13]],"date-time":"2023-12-13T00:00:00Z","timestamp":1702425600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Allergy"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Epidemiologic data on occupational anaphylaxis is scarce, and there is a need of more knowledge about work\u2010related anaphylactic episodes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Based on the data of the Anaphylaxis Registry, we identified cases related to occupational exposure and analyzed the elicitors, demographics, severity of clinical reaction and management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Since 2017, 5851 cases with an information about the occupational relation of the anaphylactic episode were registered whereby 225 (3.8%) were assigned to be caused by an occupational allergen. The vast majority of these occupational anaphylaxis cases were caused by insects (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009186, 82.7%) followed by food (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200927, 12.0%) and drugs (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20098, 3.6%). Latex elicited occupational anaphylaxis in only two cases. Beekeepers, gardeners, farmers, and individuals working in professions associated with food handling, for example, employees in restaurants, bakery, pastry, and cooks were most frequently affected. The comparison of the occupational insect venom\u2010induced anaphylaxis to a group of non\u2010occupational insect anaphylaxis in adults (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u20091842) revealed a significant younger age in occupational anaphylaxis (46 vs. 53\u2009years), a predominance of bee\u2010induced cases (38% vs. 17%), and a higher rate of venom immunotherapy in a primary care setting (3.3% vs. 1.3%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u2009.044). In the occupational\u2010 versus non\u2010occupational adults with food\u2010induced anaphylaxis atopic dermatitis as concomitant atopic disease was observed more frequently (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u2009486; 20% vs. 10%), although this was not significant.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our data demonstrate the impact of venom allergy in work\u2010related anaphylaxis. Foods and drugs are less frequently elicitors, and latex\u2010induced occupational anaphylaxis was rare. More data are needed to determine risk factors associated with occupational anaphylaxis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/all.15974","type":"journal-article","created":{"date-parts":[[2023,12,14]],"date-time":"2023-12-14T05:35:48Z","timestamp":1702532148000},"page":"702-710","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Occupational anaphylaxis\u2014Data from the anaphylaxis registry"],"prefix":"10.1111","volume":"79","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3449-1245","authenticated-orcid":false,"given":"Margitta","family":"Worm","sequence":"first","affiliation":[{"name":"Division of Allergy and Immunology, Department of Dermatology, Venereology and Allergology Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin, Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin  Berlin 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