{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T00:04:32Z","timestamp":1788998672887,"version":"build-2803163510"},"reference-count":87,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T00:00:00Z","timestamp":1763683200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T00:00:00Z","timestamp":1763683200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100023685","name":"Fraunhofer-Institut f\u00fcr Translationale Medizin und Pharmakologie","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100023685","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Allergy"],"published-print":{"date-parts":[[2026,2]]},"abstract":"ABSTRACT<\/jats:title>\n The Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines produced their first edition in 1999, with subsequent revisions in 2008, 2010, 2016 and 2019. A new iteration of ARIA\u2014ARIA 2024\u20132025\u2014in collaboration with EAACI is currently being developed, focusing on the management of allergic rhinitis. ARIA 2024\u20132025\u00a0follows the GRADE framework and is endorsed by the European Academy of Allergy and Clinical Immunology (EAACI). A set of approaches has been used to develop guideline questions, including surveying key opinion leaders and using artificial intelligence (AI)\u2010based tools to analyse web searches on allergic rhinitis and to generate questions. Each prioritised guideline question is assessed through an Evidence\u2010to\u2010Decision (EtD) framework. EtDs support the systematic and transparent formulation of recommendations, comprising 12 criteria for which the best available evidence should be sought. In the context of ARIA\u2010EAACI 2024\u20132025, such evidence is derived not only from randomised controlled trials but also\u2014among others\u2014from patient\u2010generated data sources that better reflect the affected individuals' perspectives. Moreover, ARIA\u2010EAACI 2024\u20132025 incorporates evidence on planetary health. Developed guideline recommendations will support the creation of digitalised decision algorithms and care pathways. This paper describes the methodology used to develop the person\u2010centred, digitally enabled and AI\u2010assisted ARIA\u2010EAACI 2024\u20132025. Among others, it describes (i) the development and prioritisation of guideline questions, (ii) sources of evidence for EtDs and (iii) the development of digitalised decision algorithms and care pathways.<\/jats:p>","DOI":"10.1111\/all.70100","type":"journal-article","created":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T09:25:24Z","timestamp":1763717124000},"page":"427-453","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":13,"title":["Methodology for the Development of the Allergic Rhinitis and Its Impact on Asthma (\n ARIA<\/scp>\n )\u2010EAACI 2024\u20132025 Guidelines: From Evidence\u2010to\u2010Decision Frameworks to Digitalised Shared Decision\u2010Making Algorithms"],"prefix":"10.1111","volume":"81","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4061-4766","authenticated-orcid":false,"given":"Jean","family":"Bousquet","sequence":"first","affiliation":[{"name":"Institute of Allergology, Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin Corporate Member of Freie Universit\u00e4t Berlin and Humboldt\u2010Universit\u00e4t zu Berlin Berlin Germany"},{"name":"Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology Berlin Germany"},{"name":"ARIA (Allergic Rhinitis and Its Impact on Asthma) Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernardo","family":"Sousa\u2010Pinto","sequence":"additional","affiliation":[{"name":"MEDCIDS\u2014Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine University of Porto Porto Portugal"},{"name":"CINTESIS@RISE\u2014Health Research Network, Faculty of Medicine University of Porto Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1834-3055","authenticated-orcid":false,"given":"Rafael Jos\u00e9","family":"Vieira","sequence":"additional","affiliation":[{"name":"MEDCIDS\u2014Department of Community Medicine, Information and Health Decision Sciences, Faculty of Medicine University of Porto Porto Portugal"},{"name":"CINTESIS@RISE\u2014Health Research Network, Faculty of Medicine University of Porto Porto Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holger J.","family":"Sch\u00fcnemann","sequence":"additional","affiliation":[{"name":"Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Immunology and Allergology Berlin Germany"},{"name":"Department of Health Research Methods, Evidence, and Impact & Department of Medicine McMaster University Hamilton Ontario Canada"},{"name":"Department of Biomedical Science Humanitas University, Pieve Emanuele Milan 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