{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,9]],"date-time":"2026-09-09T03:33:52Z","timestamp":1788924832473,"version":"build-2803163510"},"reference-count":7,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2012,11,5]],"date-time":"2012-11-05T00:00:00Z","timestamp":1352073600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anaesthesia"],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>Recently, increasing attention has been drawn to haemophagocytic lymphohistiocytosis as a potentially under\u2010diagnosed condition in critically ill patients with severe sepsis. It is thought to be caused by a highly stimulated, but ineffective, immune system. We report the case of a patient suffering from major burns who, despite extensive investigations showing the absence of concurrent sepsis or infection, developed haemophagocytic lymphohistiocytosis refractory to treatment. We believe that this is the first report suggestive of haemophagocytic lymphohistiocytosis triggered by a burns injury.<\/jats:p>","DOI":"10.1111\/anae.12062","type":"journal-article","created":{"date-parts":[[2012,11,5]],"date-time":"2012-11-05T04:57:22Z","timestamp":1352091442000},"page":"413-416","source":"Crossref","is-referenced-by-count":5,"title":["Haemophagocytic lymphohistiocytosis in a patient with severe burns"],"prefix":"10.1111","volume":"68","author":[{"given":"J. R. S.","family":"Porter","sequence":"first","affiliation":[{"name":"Department of Anaesthesia, Pain Medicine &amp; Intensive Care Chelsea and Westminster Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Handy","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Pain Medicine &amp; Intensive Care Chelsea and Westminster Hospital London UK"},{"name":"Imperial College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Yarranton","sequence":"additional","affiliation":[{"name":"Department of Haematology Chelsea and Westminster Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Gurney","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia, Pain Medicine &amp; Intensive Care Chelsea and Westminster Hospital London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,11,5]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-0619"},{"key":"e_1_2_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2007.05.001"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbspin.2011.10.015"},{"key":"e_1_2_5_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.21039"},{"key":"e_1_2_5_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF02982007"},{"key":"e_1_2_5_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-010-1936-z"},{"key":"e_1_2_5_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/mpo.10314"}],"container-title":["Anaesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fanae.12062","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/associationofanaesthetists-publications.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/anae.12062","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T21:44:13Z","timestamp":1761687853000},"score":1,"resource":{"primary":{"URL":"https:\/\/associationofanaesthetists-publications.onlinelibrary.wiley.com\/doi\/10.1111\/anae.12062"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,11,5]]},"references-count":7,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,4]]}},"alternative-id":["10.1111\/anae.12062"],"URL":"https:\/\/doi.org\/10.1111\/anae.12062","archive":["Portico"],"relation":{},"ISSN":["0003-2409","1365-2044"],"issn-type":[{"value":"0003-2409","type":"print"},{"value":"1365-2044","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,11,5]]}}}