{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T07:14:11Z","timestamp":1791357251735,"version":"4.3.1"},"reference-count":14,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,1,8]],"date-time":"2016-01-08T00:00:00Z","timestamp":1452211200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001136","name":"Australian and New Zealand College of Anaesthetists","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001136","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anaesthesia"],"published-print":{"date-parts":[[2016,4]]},"abstract":"Summary<\/jats:title>\n \n We allocated 76 men scheduled for radical retropubic prostatectomy to peri\u2010operative lidocaine 2% or saline 0.9%: a pre\u2010operative 0.075 ml.kg\n \u22121<\/jats:sup>\n intravenous bolus; an intra\u2010operative intravenous infusion at 0.075 ml.kg\n \u22121<\/jats:sup>\n .h\n \u22121<\/jats:sup>\n ; and 24 hours' postoperative subcutaneous infusion at 0.075 ml.kg\n \u22121<\/jats:sup>\n .h\n \u22121<\/jats:sup>\n . Lidocaine reduced the postoperative hospital stay by a mean (95%\n CI<\/jats:styled-content>\n ) of 1.3 (0.3\u20132.4) days, p = 0.017, from a mean (\n SD<\/jats:styled-content>\n ) of 4.6 (3.2) days with saline. Lidocaine reduced pain at rest during the first 24 postoperative hours by a mean (95%\n CI<\/jats:styled-content>\n ) of 1.8 (0.7\u20132.9) mm.h\n \u22121<\/jats:sup>\n , p = 0.001. Lidocaine reduced 24\u2010h morphine consumption by a mean (95%\n CI<\/jats:styled-content>\n ) of 13.9 (2.2\u201325.7) mg, p = 0.021, from a mean (\n SD<\/jats:styled-content>\n ) of 52.3 (26.9) mg with saline. There were no differences in other outcomes.\n <\/jats:p>","DOI":"10.1111\/anae.13368","type":"journal-article","created":{"date-parts":[[2016,1,10]],"date-time":"2016-01-10T10:34:37Z","timestamp":1452422077000},"page":"405-410","source":"Crossref","is-referenced-by-count":36,"title":["A randomised controlled trial of peri\u2010operative lidocaine infusions for open radical prostatectomy"],"prefix":"10.1111","volume":"71","author":[{"given":"L.","family":"Weinberg","sequence":"first","affiliation":[{"name":"Anaesthesia Peri\u2010operative and Pain Medicine University of Melbourne Melbourne Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Rachbuch","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia Eastern Health Box Hill Victoria Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Ting","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia Monash Health 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