{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T12:06:32Z","timestamp":1791893192991,"version":"4.3.4"},"reference-count":27,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2016,10,22]],"date-time":"2016-10-22T00:00:00Z","timestamp":1477094400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anaesthesia"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    Lumbar spinal surgery is most commonly performed under general anaesthesia. However, spinal anaesthesia has also been used. We aimed to systematically review the comparative evidence. We only included randomised, controlled trials in this meta\u2010analysis and calculated the risk ratio or standardised mean difference for haemodynamics, blood loss, surgical time, analgesic requirement, nausea and\/or vomiting, and length of hospital stay. Eight studies with a total of 625 patients were included. These were considered to be at high risk of bias. Compared with general anaesthesia, the risk ratio (95%\n                    <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                    ) with spinal anaesthesia for intra\u2010operative hypertension was 0.31 (0.15\u20130.64), I\n                    <jats:sup>2<\/jats:sup>\n                    = 0% (p = 0.002); for intra\u2010operative tachycardia 0.51 (0.30\u20130.84), I\n                    <jats:sup>2<\/jats:sup>\n                    = 0% (p = 0.009); for analgesic requirement in the postanaesthesia care unit 0.32 (0.24\u20130.43), I\n                    <jats:sup>2<\/jats:sup>\n                    = 0% (p &lt; 0.0001); and for nausea\/vomiting within 24 h postoperatively 0.29 (0.18\u20130.46), I\n                    <jats:sup>2<\/jats:sup>\n                    = 12% (p &lt; 0.00001). The standardised mean difference (95%\n                    <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                    ) for hospital stay was \u22121.15 (\u22121.98 to \u22120.31), I\n                    <jats:sup>2<\/jats:sup>\n                    = 89% (p = 0.007). There was no evidence of a difference in intra\u2010operative hypotension and bradycardia, blood loss, surgical time, analgesic requirement within 24 h postoperatively, and nausea\/vomiting in the postanaesthesia care unit. We conclude that spinal anaesthesia appears to offer advantages over general anaesthesia for lumbar spine surgery.\n                  <\/jats:p>","DOI":"10.1111\/anae.13702","type":"journal-article","created":{"date-parts":[[2016,10,22]],"date-time":"2016-10-22T02:32:52Z","timestamp":1477103572000},"page":"391-401","source":"Crossref","is-referenced-by-count":73,"title":["Impact of spinal anaesthesia vs. general anaesthesia on peri\u2010operative outcome in lumbar spine surgery: a systematic review and meta\u2010analysis of randomised, controlled trials"],"prefix":"10.1111","volume":"72","author":[{"given":"T.","family":"Meng","sequence":"first","affiliation":[{"name":"Department of Anaesthesia Nanfang Hospital Southern Medical University Guangzhou Guangdong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.","family":"Zhong","sequence":"additional","affiliation":[{"name":"Department of Spine Surgery Nanfang Hospital Southern Medical University Guangzhou Guangdong Province China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Meng","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Yale University School of Medicine New Haven Connecticut USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,10,22]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0952-8180(98)00112-3"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.3171\/spi.2005.2.1.0017"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.brs.0000144834.43115.38"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.4172\/2155-6148.1000402"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00101-013-2204-8"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2014.08.024"},{"key":"e_1_2_6_8_1","first-page":"685","article-title":"Lumbar microdiscectomy under spinal and general anesthesia: a comparative study","volume":"25","author":"Dagistan Y","year":"2015","journal-title":"Turkish Neurosurgery"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pjnns.2014.05.005"},{"key":"e_1_2_6_10_1","first-page":"380","article-title":"Comparison of patient satisfaction and cost in spinal and general anesthesia for lumbar disc surgery","volume":"24","author":"Vural C","year":"2014","journal-title":"Turkish Neurosurgery"},{"key":"e_1_2_6_11_1","first-page":"524","article-title":"Spinal anesthesia versus general anesthesia for elective lumbar spine surgery: a randomized clinical trial","volume":"16","author":"Attari MA","year":"2011","journal-title":"Journal of Research in Medical Sciences"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000539-199609000-00021"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surneu.2008.08.003"},{"key":"e_1_2_6_14_1","first-page":"CD000521","article-title":"General versus spinal\/epidural anaesthesia for surgery for hip fractures in adults","volume":"4","author":"Parker MJ","year":"2000","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2010.02.007"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d5928"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.13108"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/0197-2456(86)90046-2"},{"key":"e_1_2_6_19_1","first-page":"487","article-title":"Comparison of spinal and general anesthesia in lumbar disc surgery","volume":"28","author":"Kara I","year":"2011","journal-title":"Journal of Neurological Sciences (Turkish)"},{"key":"e_1_2_6_20_1","first-page":"586","article-title":"Neuroendocrine and hemodynamic effects of general anesthesia and spinal anesthesia for minimally invasive lumbar disc surgery: a randomized trial","volume":"31","author":"Yildirim Guclu C","year":"2014","journal-title":"Journal of Neurological Sciences (Turkish)"},{"key":"e_1_2_6_21_1","first-page":"206","article-title":"[Regional anesthesia for lumbar microdiscectomy]","volume":"50","author":"Dagher C","year":"2002","journal-title":"Journal Medical Libanais"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2014.01.016"},{"key":"e_1_2_6_23_1","first-page":"1","article-title":"Regional versus general anesthesia for spine surgery. 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