{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T08:31:25Z","timestamp":1781512285968,"version":"3.54.1"},"reference-count":40,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2017,6,12]],"date-time":"2017-06-12T00:00:00Z","timestamp":1497225600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Anaesthesia"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    We evaluated whether pre\u2010emptive analgesia with a pre\u2010operative ultrasound\u2010guided infraclavicular brachial plexus block resulted in better postoperative analgesia than an identical block performed postoperatively. Fifty\u2010two patients undergoing fixation of a fractured radius were included. All patients received general anaesthesia with remifentanil and propofol. Patients were randomly allocated into two groups: a pre\u2010operative block or a postoperative block with 0.5 ml.kg\n                    <jats:sup>\u22121<\/jats:sup>\n                    ropivacaine 0.75%. After surgery, all patients received regular paracetamol plus opioids for breakthrough pain. Mean (\n                    <jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>\n                    ) time to first rescue analgesic after emergence from general anaesthesia was 544 (217) min in the pre\u2010operative block group compared with 343 (316) min in the postoperative block group (p = 0.015). Postoperative pain scores were higher and more patients required rescue analgesia during the first 4 h after surgery in the postoperative block group. There were no significant differences in plasma stress mediators between the groups. Analgesic consumption was lower at day seven in the pre\u2010operative block group. Pain was described as very strong at block resolution in 27 (63%) patients and 26 (76%) had episodes of mild pain after 6 months. We conclude that a pre\u2010operative ultrasound\u2010guided infraclavicular brachial plexus block provides longer and better analgesia in the acute postoperative period compared with an identical postoperative block in patients undergoing surgery for fractured radius.\n                  <\/jats:p>","DOI":"10.1111\/anae.13939","type":"journal-article","created":{"date-parts":[[2017,6,12]],"date-time":"2017-06-12T01:48:38Z","timestamp":1497232118000},"page":"967-977","source":"Crossref","is-referenced-by-count":21,"title":["Pre\u2010operative brachial plexus block compared with an identical block performed at the end of surgery: a prospective, double\u2010blind, randomised clinical trial"],"prefix":"10.1111","volume":"72","author":[{"given":"A.","family":"Holmberg","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology Oslo University Hospital Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. R.","family":"Sauter","sequence":"additional","affiliation":[{"name":"Department of Research and Development Division of Emergencies and Critical Care Oslo University hospital Oslo Norway"},{"name":"Department of Anaesthesiology and Pain Medicine Inselspital, Bern University Hospital University of Bern Bern Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d8.","family":"Klaastad","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology University Hospital of North Norway Troms\u00f8 Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Dr\u00e6gni","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology Oslo University Hospital Oslo Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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