{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,3]],"date-time":"2026-02-03T16:36:22Z","timestamp":1770136582216,"version":"3.49.0"},"reference-count":38,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2019,9,13]],"date-time":"2019-09-13T00:00:00Z","timestamp":1568332800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100011102","name":"Seventh Framework Programme","doi-asserted-by":"publisher","award":["602150"],"award-info":[{"award-number":["602150"]}],"id":[{"id":"10.13039\/100011102","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007731","name":"ZNS - Hannelore Kohl Stiftung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007731","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["associationofanaesthetists-publications.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Anaesthesia"],"published-print":{"date-parts":[[2020,1]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>Traumatic brain injury patients frequently undergo tracheal intubation. We aimed to assess current intubation practice in Europe and identify variation in practice. We analysed data from patients with traumatic brain injury included in the prospective cohort study collaborative European neurotrauma effectiveness research in traumatic brain injury (CENTER\u2010TBI) in 45 centres in 16 European countries. We included patients who were transported to hospital by emergency medical services. We used mixed\u2010effects multinomial regression to quantify the effects on pre\u2010hospital or in\u2010hospital tracheal intubation of the following: patient characteristics; injury characteristics; centre; and trauma system characteristics. A total of 3843 patients were included. Of these, 1322 (34%) had their tracheas intubated; 839 (22%) pre\u2010hospital and 483 (13%) in\u2010hospital. The fit of the model with only patient characteristics predicting intubation was good (Nagelkerke R2 64%). The probability of tracheal intubation increased with the following: younger age; lower pre\u2010hospital or emergency department GCS; higher abbreviated injury scale scores (head and neck, thorax and chest, face or abdomen abbreviated injury score); and one or more unreactive pupils. The adjusted median odds ratio for intubation between two randomly chosen centres was 3.1 (95%CI 2.1\u20134.3) for pre\u2010hospital intubation, and 2.7 (95%CI 1.9\u20133.5) for in\u2010hospital intubation. Furthermore, the presence of an anaesthetist was independently associated with more pre\u2010hospital intubation (OR 2.9, 95%CI 1.3\u20136.6), in contrast to the presence of ambulance personnel who are allowed to intubate (OR 0.5, 95%CI 0.3\u20130.8). In conclusion, patient and injury characteristics are key drivers of tracheal intubation. Between\u2010centre differences were also substantial. Further studies are needed to improve the evidence base supporting recommendations for tracheal intubation.<\/jats:p>","DOI":"10.1111\/anae.14838","type":"journal-article","created":{"date-parts":[[2019,9,14]],"date-time":"2019-09-14T00:14:06Z","timestamp":1568420046000},"page":"45-53","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":20,"title":["Variation in the practice of tracheal intubation in Europe after traumatic brain injury: a prospective cohort study"],"prefix":"10.1111","volume":"75","author":[{"given":"B. Y.","family":"Gravesteijn","sequence":"first","affiliation":[{"name":"Departments of Anesthesiology and Public Health Erasmus University Medical Centre Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. A.","family":"Sewalt","sequence":"additional","affiliation":[{"name":"Department of Public Health Erasmus University Medical Centre Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Ercole","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology University of Cambridge UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Lecky","sequence":"additional","affiliation":[{"name":"Emergency Medicine Research in Sheffield School of Health and Related Research Faculty of Medicine, Dentistry and Health University of Sheffield UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Menon","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia University of Cambridge UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. W.","family":"Steyerberg","sequence":"additional","affiliation":[{"name":"Department of Biostatistics Leiden University Medical Centre Leiden The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. I. R.","family":"Maas","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery University Hospital Antwerp Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H. F.","family":"Lingsma","sequence":"additional","affiliation":[{"name":"Department of Public Health Erasmus University Medical Centre Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Klimek","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Erasmus University Medical Centre Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"the CENTER\u2010TBI collaborators","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,9,13]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(17)30371-X"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-2667(16)30017-2"},{"key":"e_1_2_6_4_1","unstructured":"Advanced Trauma Life Support. 9th 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