{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,9]],"date-time":"2026-11-09T12:12:55Z","timestamp":1794226375719,"version":"4.9.0"},"reference-count":30,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2019,9,19]],"date-time":"2019-09-19T00:00:00Z","timestamp":1568851200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["associationofanaesthetists-publications.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Anaesthesia"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    Thoracic interfascial plane blocks are effective for post\u2010mastectomy acute analgesia. However, their effects on chronic pain are uncertain. We randomly allocated 80 women equally to pectoral nerve\u20102 (PECS 2) block or serratus plane block. The pectoral nerve\u20102 block reduced the rate of moderate or severe chronic pain from 13\/40 (33%) with the serratus plane block to 4\/40 (10%), p = 0.03, adjusted odds ratio (95%CI) 0.23 (0.07\u20130.80), p\u00a0=\u00a00.02. The rates of pain\u2010free women at six postoperative months were indeterminate, 10\/40 (25%) after serratus plane block vs. 19\/40 (48%) after pectoral nerve\u20102 block, p\u00a0=\u00a00.06, adjusted odds ratio (95%CI) 2.9 (1.1\u20137.5), p\u00a0=\u00a00.03. Health\u2010related quality of life at six postoperative months was similar after serratus plane and pectoral nerve\u20102 blocks, mean (\n                    <jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>\n                    )\n                    <jats:styled-content style=\"fixed-case\">EQ<\/jats:styled-content>\n                    \u20105D\u20103L scores 0.87 (0.15) vs. 0.91 (0.14), respectively, p\u00a0=\u00a00.21. The pectoral nerve\u20102 block reduced median (\n                    <jats:styled-content style=\"fixed-case\">IQR<\/jats:styled-content>\n                    [range]) morphine consumption in the first 24 postoperative hours from 6 (3\u20139 [1\u201325])\u00a0mg to 4 (2\u20137 [0\u201337]) mg, p\u00a0=\u00a00.04. However, acute pain scores after serratus plane and pectoral nerve\u20102 blocks were similar, median (\n                    <jats:styled-content style=\"fixed-case\">IQR<\/jats:styled-content>\n                    [range]) 23 (11\u201335 [0\u201370])\u00a0mm vs. 18 (11\u201327 [0\u201361])\u00a0mm, respectively, p\u00a0=\u00a00.44. Pectoral nerve\u20102 block reduced chronic pain 6\u00a0months after mastectomy compared with serratus plane block.\n                  <\/jats:p>","DOI":"10.1111\/anae.14856","type":"journal-article","created":{"date-parts":[[2019,9,19]],"date-time":"2019-09-19T05:52:38Z","timestamp":1568872358000},"page":"1558-1562","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":58,"title":["A randomised controlled trial of pectoral nerve\u20102 (\n                    <scp>PECS<\/scp>\n                    2) block vs. serratus plane block for chronic pain after mastectomy"],"prefix":"10.1111","volume":"74","author":[{"given":"T.","family":"Fujii","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology Nagoya University Graduate School of Medicine Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Shibata","sequence":"additional","affiliation":[{"name":"Department of Surgery Nagoya University Hospital Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Akane","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology Nagoya University Hospital Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.","family":"Aoki","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology Nagoya University Hospital Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Sekiguchi","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology Nagoya University Hospital Nagoya Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Department of Biostatistics Nagoya University Graduate School of Medicine Nagoya 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