{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T20:34:57Z","timestamp":1784666097861,"version":"3.55.0"},"reference-count":16,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2019,12,23]],"date-time":"2019-12-23T00:00:00Z","timestamp":1577059200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["associationofanaesthetists-publications.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Anaesthesia"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    Laryngeal surgery requires a shared airway and close collaboration between surgeon and anaesthetist in order to optimise operating conditions. Apnoeic oxygenation uses the principle of aventilatory mass flow to maintain oxygenation of pulmonary capillary blood under apnoeic conditions while minimising laryngeal movement. Concerns regarding accumulation of carbon dioxide and resultant acidaemia have limited the use of the technique. We performed a prospective study of low\u2010flow apnoeic oxygenation for patients undergoing microlaryngoscopy under general anaesthesia in order to evaluate the ability of the technique to maintain oxygenation and determine the resultant rate of carbon dioxide accumulation. Sixty\u2010four patients undergoing microlaryngoscopy under general anaesthesia were studied between November 2016 and December 2018. Intra\u2010operative oxygenation was provided via a 10\u2010French oxygen catheter placed into the trachea delivering oxygen at 0.5\u20131.0\u00a0l.min\n                    <jats:sup>\u22121<\/jats:sup>\n                    . Data regarding apnoea time, peripheral oxygen saturation and venous blood gas concentrations were recorded. The mean (\n                    <jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>\n                    ) duration of apnoea was 18.7 (7.2) min. Apnoeic oxygenation allowed successful completion of the surgical procedure in 62\/64 patients. Mean (\n                    <jats:styled-content style=\"fixed-case\">SD<\/jats:styled-content>\n                    ) rate of rise of the venous partial pressure of carbon dioxide was 0.15 (0.10)\n                    <jats:styled-content style=\"fixed-case\">kP<\/jats:styled-content>\n                    a.min\n                    <jats:sup>\u22121<\/jats:sup>\n                    . Operating conditions were recorded qualitatively as being adequate in all cases. No adverse effects were reported. Low\u2010flow intra\u2010tracheal apnoeic oxygenation is a simple, effective and inexpensive technique to maintain oxygenation for laryngeal surgery.\n                  <\/jats:p>","DOI":"10.1111\/anae.14959","type":"journal-article","created":{"date-parts":[[2019,12,23]],"date-time":"2019-12-23T23:13:16Z","timestamp":1577142796000},"page":"1070-1075","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":18,"title":["Low\u2010flow apnoeic oxygenation for laryngeal surgery: a prospective observational study"],"prefix":"10.1111","volume":"75","author":[{"given":"C. J.","family":"O'Loughlin","sequence":"first","affiliation":[{"name":"Department of Anaesthesia Frankston Private Hospital Frankston Vic. Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. J.","family":"Phyland","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery School of Clinical Sciences (Monash Health) Monash University Clayton Vic. Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. A.","family":"Vallance","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery School of Clinical Sciences (Monash Health) Monash University Clayton Vic. Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Giddings","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, Head and Neck Surgery School of Clinical Sciences (Monash Health) Monash University Clayton Vic. Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Malkoutzis","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia Monash Health Clayton Vic. Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Gunasekera","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia Frankston Private Hospital Frankston Vic. Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Webb","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia Frankston Private Hospital Frankston Vic. Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Barnes","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia Monash Health Clayton Vic. Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,12,23]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199609000-00011"},{"key":"e_1_2_6_3_1","first-page":"242","article-title":"Anaesthesia for laryngo\u2010tracheal surgery, including tubeless field techniques","volume":"17","author":"Pearson KL","year":"2017","journal-title":"British Journal of Anaesthesia Education"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.14565"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.12923"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aex036"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.14036"},{"key":"e_1_2_6_8_1","first-page":"366","article-title":"Apneic oxygenation with high\u2010flow nasal cannula and transcutaneous carbon dioxide monitoring during airway surgery: a case series","volume":"12","author":"Ebeling CG","year":"2019","journal-title":"Anesthesia and Analgesia"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1177\/0194599813486248"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-195911000-00007"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-197312000-00006"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-196105000-00013"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0952-8180(89)90070-6"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000003810"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/resp.12225"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.14848"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.1985.tb02228.x"}],"container-title":["Anaesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fanae.14959","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/anae.14959","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/anae.14959","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/associationofanaesthetists-publications.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/anae.14959","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T16:31:44Z","timestamp":1761669104000},"score":1,"resource":{"primary":{"URL":"https:\/\/associationofanaesthetists-publications.onlinelibrary.wiley.com\/doi\/10.1111\/anae.14959"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,23]]},"references-count":16,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2020,8]]}},"alternative-id":["10.1111\/anae.14959"],"URL":"https:\/\/doi.org\/10.1111\/anae.14959","archive":["Portico"],"relation":{},"ISSN":["0003-2409","1365-2044"],"issn-type":[{"value":"0003-2409","type":"print"},{"value":"1365-2044","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,23]]},"assertion":[{"value":"2019-11-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-12-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}