{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T18:52:22Z","timestamp":1774983142212,"version":"3.50.1"},"reference-count":26,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2020,5,15]],"date-time":"2020-05-15T00:00:00Z","timestamp":1589500800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Minister Erna Hamilton's Legat for Videnskab og Kunst"},{"name":"Oberstinde Kirsten Jensa La Cours Forskningslegat"},{"name":"Investigator-Initiated Studies Program of Merck Sharp & Dohme Corp"}],"content-domain":{"domain":["associationofanaesthetists-publications.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Anaesthesia"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>\n                    Timely application of objective neuromuscular monitoring can avoid residual neuromuscular blockade. We assessed the frequency of objective neuromuscular monitoring with acceleromyography and the last recorded train\u2010of\u2010four ratio in a cohort of Danish patients. We extracted data from all patients receiving general anaesthesia from November 2014 to November 2016 at six hospitals in the Zealand Region of Denmark. Acceleromyography was available in all operating rooms and data were recorded automatically. The primary outcome measure was acceleromyography use in patients receiving neuromuscular blocking agents, divided into non\u2010depolarising agents and succinylcholine only. The dataset included 76,743 cases, of which 30,430 received a neuromuscular blocking drug. Non\u2010depolarising drugs were used in 16,525 (54%) and succinylcholine as the sole drug in 13,905 (46%) cases. Acceleromyography was used in 14,463 (88%) patients who received a non\u2010depolarising neuromuscular blocking drug and in 4224 (30%) receiving succinylcholine alone. Acceleromyography use varied between the departments from 58% to 99% for non\u2010depolarising drugs and from 3% to 79% for succinylcholine alone. The median (\n                    <jats:styled-content style=\"fixed-case\">IQR<\/jats:styled-content>\n                    [range]) of the last recorded train\u2010of\u2010four ratio before tracheal extubation was 0.97 (0.90\u20131.06 [0.01\u20132.20]) when non\u2010depolarising drugs were used, and was less than 0.9 in 22% of cases. The\n                    <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                    for oxygen desaturation was higher with the use of succinylcholine [2.51 (95%\n                    <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                    2.33\u20132.70) p\u00a0&lt;\u00a00.001] and non\u2010depolarising drugs [2.57 (95%\n                    <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                    2.32\u20132.84) p\u00a0&lt;\u00a00.001] as compared with cases where no neuromuscular blockade drug was used. In conclusion, acceleromyography was almost always used in cases where non\u2010depolarising neuromuscular blocking drugs were used, but a train\u2010of\u2010four ratio of 0.9 was not always achieved. Monitoring was used in less than 30% of cases where succinylcholine was the sole drug used.\n                  <\/jats:p>","DOI":"10.1111\/anae.15083","type":"journal-article","created":{"date-parts":[[2020,5,16]],"date-time":"2020-05-16T01:14:20Z","timestamp":1589591660000},"page":"1164-1172","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["A retrospective observational study of neuromuscular monitoring practice in 30,430 cases from six Danish hospitals"],"prefix":"10.1111","volume":"75","author":[{"given":"J. L. D.","family":"Thomsen","sequence":"first","affiliation":[{"name":"Department of Anaesthesiology, Herlev and Gentofte Hospital University of Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. K.","family":"Staehr\u2010Rye","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Herlev and Gentofte Hospital University of Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Mathiesen","sequence":"additional","affiliation":[{"name":"Center of Anaesthesiological Research Department of Anaesthesiology Zealand University Hospital K\u00f8ge Denmark"},{"name":"Department of Clinical Medicine University of Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"H\u00e4gi\u2010Pedersen","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology N\u00e6stved\u2010Slagelse\u2010Ringsted Hospitals Denmark"},{"name":"Department of Regional Health Research The Faculty of Health Sciences University of Southern Denmark Odense Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. R.","family":"G\u00e4tke","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Herlev and Gentofte Hospital University of Copenhagen Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2020,5,15]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e3181e1d94c"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200305000-00002"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e3182342840"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e318182af3b"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0000000000001409"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aev096"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9185.173366"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.2009.02131.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e3181c07428"},{"key":"e_1_2_6_11_1","first-page":"3878","article-title":"Does evidence lead to a change in clinical practice? 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