{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T21:29:02Z","timestamp":1789680542391,"version":"4.0.1"},"reference-count":26,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2021,8,9]],"date-time":"2021-08-09T00:00:00Z","timestamp":1628467200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100000272","name":"National Institute for Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007872","name":"Bowel and Cancer Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007872","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000863","name":"Bowel Disease Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000863","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009756","name":"Sarcoma UK","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009756","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007568","name":"Urology Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007568","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["associationofanaesthetists-publications.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Anaesthesia"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>We aimed to determine the impact of pre\u2010operative isolation on postoperative pulmonary complications after elective surgery during the global SARS\u2010CoV\u20102 pandemic. We performed an international prospective cohort study including patients undergoing elective surgery in October 2020. Isolation was defined as the period before surgery during which patients did not leave their house or receive visitors from outside their household. The primary outcome was postoperative pulmonary complications, adjusted in multivariable models for measured confounders. Pre\u2010defined sub\u2010group analyses were performed for the primary outcome. A total of 96,454 patients from 114 countries were included and overall, 26,948 (27.9%) patients isolated before surgery. Postoperative pulmonary complications were recorded in 1947 (2.0%) patients of which 227 (11.7%) were associated with SARS\u2010CoV\u20102 infection. Patients who isolated pre\u2010operatively were older, had more respiratory comorbidities and were more commonly from areas of high SARS\u2010CoV\u20102 incidence and high\u2010income countries. Although the overall rates of postoperative pulmonary complications were similar in those that isolated and those that did not (2.1% vs 2.0%, respectively), isolation was associated with higher rates of postoperative pulmonary complications after adjustment (adjusted OR 1.20, 95%CI 1.05\u20131.36, p\u00a0=\u00a00.005). Sensitivity analyses revealed no further differences when patients were categorised by: pre\u2010operative testing; use of COVID\u201019\u2010free pathways; or community SARS\u2010CoV\u20102 prevalence. The rate of postoperative pulmonary complications increased with periods of isolation longer than 3\u00a0days, with an OR (95%CI) at 4\u20137\u00a0days or \u2265\u00a08\u00a0days of 1.25 (1.04\u20131.48), p\u00a0=\u00a00.015 and 1.31 (1.11\u20131.55), p\u00a0=\u00a00.001, respectively. Isolation before elective surgery might be associated with a small but clinically important increased risk of postoperative pulmonary complications. Longer periods of isolation showed no reduction in the risk of postoperative pulmonary complications. These findings have significant implications for global provision of elective surgical care.<\/jats:p>","DOI":"10.1111\/anae.15560","type":"journal-article","created":{"date-parts":[[2021,8,9]],"date-time":"2021-08-09T18:01:16Z","timestamp":1628532076000},"page":"1454-1464","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":55,"title":["Effects of pre\u2010operative isolation on postoperative pulmonary complications after elective surgery: an international prospective cohort study"],"prefix":"10.1111","volume":"76","author":[{"name":"COVIDSurg Collaborative","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"GlobalSurg Collaborative","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,8,9]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)31182-X"},{"key":"e_1_2_6_3_1","first-page":"88","article-title":"Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS\u2010CoV\u20102 pandemic. Bristish","volume":"108","author":"COVIDSurg Collaborative","year":"2021","journal-title":"Journal of Surgery"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.20.01933"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2021.100865"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(21)00129-6"},{"key":"e_1_2_6_7_1","unstructured":"National Institute for Health and Care Excellence.COVID\u201019 rapid guideline: arranging planned care in hospitals and diagnostic services. 27\/07\/2020.www.nice.org.uk\/guidance\/ng179(accessed 29\/06\/2021)."},{"key":"e_1_2_6_8_1","unstructured":"Associacion Espanola de Cirurgia Mayor Ambulatoria.Recomendaciones para la reapertura de las unidades de CMA durante el periodo de transicion de la pandemia por el COVID\u201019 (SARS\u2010CoV\u20102). 02\/09\/2020.https:\/\/www.asecma.org\/documentos\/Recomendaciones\u2010apertura\u2010CMA\u2010tras\u2010Covid.pdf(accessed 29\/06\/2021)."},{"key":"e_1_2_6_9_1","unstructured":"AmaralC OrfaoR LancaF AzenhaM. Recomendacoes para retoma da atividade cirurgica electiva apos condicionamento pela pandemia COVID\u201019.http:\/\/www.spanestesiologia.pt\/webstspa\/wp\u2010content\/uploads\/2020\/05\/recomendacoes\u2010de\u2010anestesiologia\u2010obstetrica_final_04052020.pdf(accessed 29\/06\/2021)."},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.15458"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39335.541782.AD"},{"key":"e_1_2_6_12_1","unstructured":"Our World in Data. Coronavirus Pandemic (COVID\u201019).https:\/\/ourworldindata.org\/coronavirus(accessed 01\/06\/2021)."},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)00001-5"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2020.113339"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17186469"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(21)00151-6"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.5114\/biolsport.2020.96857"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11764-017-0645-9"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/ecc.13023"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2019.07.032"},{"key":"e_1_2_6_21_1","unstructured":"SilverJK SellN ParangiS QadanM.Prehabilitation may influence surgical morbidity and mortality during and after the covid\u201019 pandemic. May 2020.https:\/\/blogs.bmj.com\/bmj\/2020\/05\/21\/prehabilitation\u2010may\u2010influence\u2010surgical\u2010morbidity\u2010and\u2010mortality\u2010during\u2010and\u2010after\u2010the\u2010covid\u201019\u2010pandemic(accessed 10\/07\/2021)."},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.10151"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.15464"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.0332"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n334"},{"key":"e_1_2_6_26_1","first-page":"714","article-title":"How to conduct an outpatient telemedicine rehabilitation or prehabilitation visit","volume":"12","author":"Verduzco\u2010Gutierrez M","year":"2020","journal-title":"Physical Medicine and Rehabilitation"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000004002"}],"container-title":["Anaesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/anae.15560","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/anae.15560","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/associationofanaesthetists-publications.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/anae.15560","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T23:03:32Z","timestamp":1761692612000},"score":1,"resource":{"primary":{"URL":"https:\/\/associationofanaesthetists-publications.onlinelibrary.wiley.com\/doi\/10.1111\/anae.15560"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8,9]]},"references-count":26,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2021,11]]}},"alternative-id":["10.1111\/anae.15560"],"URL":"https:\/\/doi.org\/10.1111\/anae.15560","archive":["Portico"],"relation":{},"ISSN":["0003-2409","1365-2044"],"issn-type":[{"value":"0003-2409","type":"print"},{"value":"1365-2044","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8,9]]},"assertion":[{"value":"2021-07-14","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-09","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}