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The aim of this review is to provide clinicians with a summary of recent studies of direct relevance to the management of traumatic brain injury in order to promote best clinical practice. The use of tranexamic acid in the management of traumatic brain injury has been the focus of several studies, with one large randomised controlled trial suggesting a reduction in all\u2010cause mortality within 24\u2009h of injury. The use of therapeutic hypothermia does not improve neurological outcomes and maintenance of normothermia remains the optimal management strategy. For seizure management, levetiracetam appears to be as effective as phenytoin, but the optimal dose remains unclear. There has been a lack of clear outcome benefit for any individual osmotherapy agent, with no difference in mortality or neurological recovery. Early tracheostomy (&lt; 7\u2009days from injury) for patients with traumatic brain injury is associated with a reduction in the incidence of ventilator\u2010associated pneumonia and duration of mechanical ventilation, critical care and hospital stay. Further research is needed in order to determine the optimal package of care and interventions. There is a need for research studies to focus on patient\u2010centred outcome measures such as long\u2010term neurological recovery and quality of life.<\/jats:p>","DOI":"10.1111\/anae.15608","type":"journal-article","created":{"date-parts":[[2022,1,10]],"date-time":"2022-01-10T04:03:37Z","timestamp":1641787417000},"page":"102-112","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":101,"title":["Management of traumatic brain injury: a narrative review of current evidence"],"prefix":"10.1111","volume":"77","author":[{"given":"M. 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