{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:44:03Z","timestamp":1787013843274,"version":"build-2736575974"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2022,3,3]],"date-time":"2022-03-03T00:00:00Z","timestamp":1646265600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["associationofanaesthetists-publications.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Anaesthesia"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:p>General or regional anaesthesia can be used for chronic subdural haematoma evacuation, but no study has compared these types of anaesthesia in terms of peri\u2010operative outcomes. This single\u2010centre, prospective, randomised study included adult patients (age\u2009\u2265\u200918\u2009years) undergoing surgical chronic subdural haematoma evacuation. Patients were randomly allocated to general (target\u2010controlled total intravenous anaesthesia with propofol and remifentanil) or regional anaesthesia (bilateral scalp block with remifentanil sedation if required). The primary outcome measure was duration of hospital stay, based on the day patients were judged by an investigator blinded from the allocation group to be medically fit for discharge. Secondary outcomes included: rate of regional anaesthesia failure; rate of intra\u2010operative and postoperative adverse events at 24\u2009hours; and pain scores at 24\u2009hours. Data from 60 patients were analysed (30 general anaesthesia and 30 regional anaesthesia). Median (IQR [range]) time until patients were judged medically fit for discharge was 3 (3\u20133 [2\u201310]) days and 3 (2\u20135 [2\u201315]) days for general and regional anaesthesia, respectively (p\u2009=\u20090.700). Regional anaesthesia failed in two patients. There were more intra\u2010operative adverse events in patients who received general anaesthesia (25 vs. 11, respectively; p\u2009=\u20090.001). The occurrence of postoperative adverse events was similar for general and regional anaesthesia (16 vs. 13 patients, respectively; p\u2009=\u20090.605). In patients requiring chronic subdural haematoma evacuation, general and regional anaesthesia are comparable in terms of duration of time until medically fit for discharge and occurrence of postoperative complications. The rate of intra\u2010operative adverse events (mainly arterial hypotension) is greater with general anaesthesia.<\/jats:p>","DOI":"10.1111\/anae.15667","type":"journal-article","created":{"date-parts":[[2022,3,3]],"date-time":"2022-03-03T06:39:31Z","timestamp":1646289571000},"page":"547-554","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Time to medical fitness for discharge following surgical evacuation of chronic subdural haematoma with general or regional anaesthesia: a prospective randomised trial"],"prefix":"10.1111","volume":"77","author":[{"given":"R.","family":"Hestin","sequence":"first","affiliation":[{"name":"Caen University Hospital and Caen Normandy University Caen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.","family":"Kamga Totouom","sequence":"additional","affiliation":[{"name":"Caen University Hospital and Caen Normandy University Caen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Gaberel","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery Caen University Hospital and Caen Normandy University Caen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. J.","family":"Parienti","sequence":"additional","affiliation":[{"name":"Department of Clinical Research and Biostatistics Caen University Hospital and Caen Normandy University Caen France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1845-8610","authenticated-orcid":false,"given":"J. L.","family":"Hanouz","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology and Intensive Care Caen University Hospital and Caen Normandy University Caen France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,3,3]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2020.06.140"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.3171\/2016.9.JNS16623"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.3171\/2014.9.JNS141550"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61115-6"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2020473"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.3171\/2016.8.JNS16134.test"},{"key":"e_1_2_6_8_1","first-page":"e037385","article-title":"Identification of factors associated with morbidity and postoperative length of stay in surgically 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