{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:15:45Z","timestamp":1787066145477,"version":"build-2736575974"},"reference-count":13,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T00:00:00Z","timestamp":1728259200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["associationofanaesthetists-publications.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Anaesthesia"],"published-print":{"date-parts":[[2025,3]]},"abstract":"Summary<\/jats:title>\n \n Background<\/jats:title>\n Type A aortic dissection repair is one of the most common emergency cardiac surgical procedures undertaken in the UK and has a high mortality. Early diagnosis and prompt surgery by an expert cardiac surgical team is crucial. Little is known about the patient's journey from first symptoms until surgery.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n The Association for Cardiothoracic Anaesthesia and Critical Care undertook a prospective national audit of the management of type A aortic dissection in the UK.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n The details of 334 patients with type A aortic dissection were reported by 28 UK cardiac centres over 12\u2009months. Median (IQR [range]) time from onset of symptoms until arrival in an emergency department was 2.3 (1.4\u20134.7 [0.1\u2013491.6]) h. Median (IQR [range]) time between arrival in the emergency department and the start of surgery was 9.5 (6.1\u201318.2 [0.8\u2013363.5]) h. Delays in diagnosis and transfers were reported in 158 (47.3%) patients. Fifty\u2010two patients (15.6%) had an initial misdiagnosis. The condition of 56 patients (16.8%) deteriorated clinically before arrival in the operating theatre. A medical doctor accompanied 50 patients (15.0%) during transfer. Sixty\u2010four patients (19.2%) died in hospital with 41 (12.3%) dying within the first 5\u2009days after surgery.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n This audit provides a snapshot of current practice for patients with type A aortic dissection in the UK. Our findings show the acuity, clinical severity and vulnerability of patients with type A aortic dissection, and the deficits in the process of diagnosis and the quality of transfer. This audit demonstrates the need for the implementation of comprehensive, regionally governed, interdisciplinary medical management for every patient with type A aortic dissection.<\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/anae.16443","type":"journal-article","created":{"date-parts":[[2024,10,7]],"date-time":"2024-10-07T04:05:21Z","timestamp":1728273921000},"page":"248-258","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Time critical diagnoses and transfers of patients with acute type A aortic dissection in the\n UK<\/scp>\n : national audit of current practice*"],"prefix":"10.1111","volume":"80","author":[{"given":"Tom","family":"Gilbey","sequence":"first","affiliation":[{"name":"Department of Anaesthesia King's College Hospital NHS Foundation Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1804-6125","authenticated-orcid":false,"given":"Benjamin","family":"Milne","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia King's College Hospital NHS Foundation Trust London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seema","family":"Agarwal","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia Manchester Foundation Trust Manchester UK"},{"name":"University of Manchester Manchester UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siu\u2010Wai","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics and Traumatology University of Hong Kong Hong Kong SAR"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Kendall","sequence":"additional","affiliation":[{"name":"NHS England North\u2010West Region UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph E.","family":"Arrowsmith","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia Royal Papworth Hospital NHS Foundation Trust Cambridge UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gudrun","family":"Kunst","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia King's College Hospital NHS Foundation Trust London UK"},{"name":"School of Cardiovascular and Metabolic Medicine and Sciences King's College London London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the ACTACC Linkperson Network","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10,7]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.5837\/bjc.2023.009"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/17511437231162219"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.m304"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehab586"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2022.09.034"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.15070"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.14734"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0000000000002453"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140\u20106736(22)01970\u20105"},{"key":"e_1_2_6_11_1","unstructured":"NHS England.Supra\u2010regional SOP on the Acute Management of Aortic Dissections. 2024.https:\/\/www.england.nhs.uk\/south\/wp\u2010content\/uploads\/sites\/6\/2024\/02\/South\u2010England\u2010Supra\u2010regional\u2010SOP\u2010on\u2010the\u2010Acute\u2010Management\u2010of\u2010Aortic\u2010Dissections\u2010v1.0\u2010FINAL\u20101.pdf(accessed 01\/05\/2024)."},{"key":"e_1_2_6_12_1","unstructured":"Society for Cardiothoracic Surgery in Great Britain and Ireland.Acute Aortic Dissection Pathway Toolkit 2022.https:\/\/scts.org\/_userfiles\/pages\/files\/aortic%20dissection\/acute_aortic_dissection_toolkit_final_20220315.pdf(accessed 01\/05\/2024)."},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/emermed\u20102023\u2010213362"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.2147\/AMEP.S259908"}],"container-title":["Anaesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/associationofanaesthetists-publications.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/anae.16443","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T18:47:21Z","timestamp":1761677241000},"score":1,"resource":{"primary":{"URL":"https:\/\/associationofanaesthetists-publications.onlinelibrary.wiley.com\/doi\/10.1111\/anae.16443"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,7]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["10.1111\/anae.16443"],"URL":"https:\/\/doi.org\/10.1111\/anae.16443","archive":["Portico"],"relation":{},"ISSN":["0003-2409","1365-2044"],"issn-type":[{"value":"0003-2409","type":"print"},{"value":"1365-2044","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10,7]]},"assertion":[{"value":"2024-08-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication 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