{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:37:45Z","timestamp":1787240265148,"version":"build-2736575974"},"reference-count":34,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T00:00:00Z","timestamp":1774742400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T00:00:00Z","timestamp":1774742400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["associationofanaesthetists-publications.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Anaesthesia"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>In March 2025, the Medicines and Healthcare products Regulatory Agency published a drug safety update removing the indication of postoperative pain from the licence of prolonged\u2010release opioids and mandated discussing risks with patients. Our study assessed compliance with these recommendations 6\u2009months post\u2010publication.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross\u2010sectional survey on organisational discharge opioid prescribing practices was distributed via the National Confidential Enquiry into Patient Outcome and Death Local Reporter pathway to acute hospitals in England, Wales and Northern Ireland. Surveys targeted Day Surgery Unit managers and Drugs and Therapeutics Committee secretaries.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We received responses from 83\u2009Day Surgery Units and 70 Drug and Therapeutics Committees (approximately 68% response rate). Before March 2025, 51\/70 (73%) Trusts routinely used modified\u2010release opioids. Following the drug safety update, 59\/70 (84%) committees shared the guidance and, consequently, 38\/51 (75%) organisations that previously used modified\u2010release opioids no longer do so. However, 10\/70 (14%) units still dispensed modified\u2010release opioids. Among day surgery units dispensing opioids, only 19\/60 (32%) provided discharge letters that advised general practitioners against repeat prescriptions and 17\/60 (28%) units provided patient information on opioid risks. Formal training on acute postoperative pain management was confirmed for only 22\/83 (27%) responding units.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Six months after the drug safety update, there is evidence of significant impact, with most Trusts sharing the alert and moving away from modified\u2010release opioids. However, substantial work is still required. Key gaps include continued dispensing of modified\u2010release and combination opioids, and poor communication with patients and general practitioners regarding opioid risks and safe disposal.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/anae.70206","type":"journal-article","created":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T03:21:30Z","timestamp":1774840890000},"page":"1091-1099","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Organisational practices in postoperative opioid prescribing at discharge in\n                    <scp>UK NHS<\/scp>\n                    day surgery units: the\n                    <scp>OPIOID<\/scp>\n                    \u2010discharge survey"],"prefix":"10.1111","volume":"81","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8839-4718","authenticated-orcid":false,"given":"Ben","family":"Grodzinski","sequence":"first","affiliation":[{"name":"Department of Anaesthesia and Pain Medicine West Suffolk Hospital NHS Foundation Trust  Bury St. Edmunds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1187-5796","authenticated-orcid":false,"given":"Dileep N.","family":"Lobo","sequence":"additional","affiliation":[{"name":"Nottingham Digestive Diseases Centre, Division of Translational Medical Sciences, School of Medicine University of Nottingham, Queen's Medical Centre  Nottingham UK"},{"name":"Division of Surgery, Perelman School of Medicine University of Pennsylvania  Philadelphia PA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8907-4396","authenticated-orcid":false,"given":"Mark","family":"Rockett","sequence":"additional","affiliation":[{"name":"University Hospitals Plymouth NHS Trust  Plymouth UK"},{"name":"Plymouth University Peninsula Schools of Medicine and Dentistry  Plymouth UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2225-1535","authenticated-orcid":false,"given":"Nicholas","family":"Levy","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Pain Medicine West Suffolk Hospital NHS Foundation Trust  Bury St. Edmunds UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,3,29]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2021.6210"},{"key":"e_1_2_6_3_1","unstructured":"VarneyS.How big pharma is targeting India's booming opioid market.2019.https:\/\/www.theguardian.com\/world\/2019\/aug\/27\/india\u2010opioids\u2010crisis\u2010us\u2010pain\u2010narcotics(accessed 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17\/01\/2026)."},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40265\u2010025\u201002236\u20103"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.15460"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.16661"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.m4901"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.16055"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.16460"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.70055"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.70092"},{"key":"e_1_2_6_20_1","unstructured":"Medicines and Healthcare products Regulatory Agency.Opioids: risk of dependence and addiction.2020.https:\/\/www.gov.uk\/drug\u2010safety\u2010update\/opioids\u2010risk\u2010of\u2010dependence\u2010and\u2010addiction(accessed 18\/02\/2026)."},{"key":"e_1_2_6_21_1","unstructured":"General Medical Council.Good practice in proposing prescribing providing and managing medicines and devices.2021.https:\/\/www.gmc\u2010uk.org\/professional\u2010standards\/the\u2010professional\u2010standards\/good\u2010practice\u2010in\u2010prescribing\u2010and\u2010managing\u2010medicines\u2010and\u2010devices(accessed 17\/01\/2026)."},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.15262"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2021.02.030"},{"key":"e_1_2_6_24_1","unstructured":"Medicines and Healthcare products Regulatory Agency.Public assessment report: Modified release opioids and treatment of post\u2010operative pain.2025.https:\/\/www.gov.uk\/government\/publications\/modified\u2010release\u2010opioids\u2010and\u2010treatment\u2010of\u2010post\u2010operative\u2010pain(accessed 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crisis.2020.https:\/\/oig.hhs.gov\/reports\/all\/2020\/fdas\u2010risk\u2010evaluation\u2010and\u2010mitigation\u2010strategies\u2010uncertain\u2010effectiveness\u2010in\u2010addressing\u2010the\u2010opioid\u2010crisis\/(accessed 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