{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T21:04:52Z","timestamp":1789592692088,"version":"build-2803163510"},"reference-count":65,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T00:00:00Z","timestamp":1782172800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T00:00:00Z","timestamp":1782172800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["associationofanaesthetists-publications.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Anaesthesia"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Single\u2010injection and continuous brachial plexus block techniques are used widely for postoperative analgesia in patients undergoing shoulder surgery. Although patient\u2010reported outcomes are described in individual studies, their effects have not been synthesised comprehensively using a patient\u2010centred framework. We sought to compare the effects of single\u2010injection vs. continuous brachial plexus block techniques on patient\u2010reported outcomes in adult patients following elective shoulder surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Databases were searched from inception to October 2025 and randomised controlled trials reporting patient\u2010reported outcomes were included. Co\u2010primary outcomes were postoperative patient\u2010reported pain intensity at rest and during movement at 12\u2009h, 24\u2009h and 48\u2009h post\u2010surgery. Secondary outcomes included nausea and vomiting; sleep quality; patient satisfaction; opioid requests; and functional scores. Random\u2010effects meta\u2010analysis and trial sequential analysis were performed, with risk of bias and quality of patient\u2010reported outcome reporting assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twenty randomised controlled trials that included 1198 patients were analysed. Continuous brachial plexus blocks were associated with lower pain at rest at 12\u2009h, 24\u2009h and 48\u2009h, with mean differences (MD) of \u22121.96 (95%CI \u22122.81 to \u22121.11, p\u2009&lt;\u20090.001), \u22121.66 (95%CI \u22122.27 to \u22121.05, p\u2009&lt;\u20090.001) and\u2009\u2212\u20091.18 (95%CI \u22121.84 to \u22120.53, p\u2009&lt;\u20090.001), respectively. Pain on movement could only be pooled at 24\u2009h and 48\u2009h and showed MD \u22122.04 (95%CI \u22124.26\u20130.19, p\u2009=\u20090.07) and\u2009\u2212\u20091.30 (95%CI \u22123.67\u20131.07, p\u2009=\u20090.28) respectively. The co\u2010primary outcomes approached or exceeded the predefined minimal clinically important difference for pain scores after shoulder surgery, in favour of continuous techniques.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Continuous brachial plexus blocks are associated with better pain at rest and other patient\u2010centred outcomes following shoulder surgery, while effects on dynamic pain and long\u2010term functional recovery remain uncertain.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/anae.70249","type":"journal-article","created":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T03:32:41Z","timestamp":1782271961000},"page":"1400-1414","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Effects of single\u2010injection vs. continuous brachial plexus blocks for shoulder surgeries on patient\u2010reported outcomes: a systematic review and meta\u2010analysis with trial sequential analysis of randomised controlled trials"],"prefix":"10.1111","volume":"81","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-5596-2871","authenticated-orcid":false,"given":"Michelle","family":"Chong","sequence":"first","affiliation":[{"name":"Department of Anaesthesia and Acute Pain Medicine St. Vincent's Hospital  Melbourne VIC Australia"},{"name":"Department of Critical Care University of Melbourne  Melbourne VIC Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1775-2400","authenticated-orcid":false,"given":"Andrew","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Medicine, Dentistry and Health Sciences University of Melbourne  Melbourne VIC Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Ballantyne","sequence":"additional","affiliation":[{"name":"Department of Critical Care University of Melbourne  Melbourne VIC Australia"},{"name":"Department of Anaesthesiology and Pain Medicine Royal Melbourne Hospital  Melbourne VIC Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4356-6525","authenticated-orcid":false,"given":"Alwin","family":"Chuan","sequence":"additional","affiliation":[{"name":"South West Sydney Clinical Campus, Faculty of Medicine &amp; 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