{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T19:46:17Z","timestamp":1789674377010,"version":"4.0.1"},"reference-count":39,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,6,28]],"date-time":"2026-06-28T00:00:00Z","timestamp":1782604800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,6,28]],"date-time":"2026-06-28T00:00:00Z","timestamp":1782604800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["associationofanaesthetists-publications.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Anaesthesia"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Pulmonary artery catheters are used widely in cardiac surgery despite observed associations with worse outcomes and guidelines that recommend against their routine use. No adequately powered randomised trials are available.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The PUMA Pilot was a multicentre, randomised, parallel assignment, open\u2010label, pilot and feasibility trial conducted at three tertiary cardiac surgery centres. Eligible patients were adults undergoing coronary artery bypass grafting, aortic valve replacement or surgery on the aortic root or ascending aorta with or without aortic valve replacement, with a predicted surgical mortality of &lt;\u20092%. Patients were allocated randomly to receive a pulmonary artery catheter or a central venous catheter inserted immediately before surgery. The primary feasibility outcome was protocol compliance, defined as receiving the assigned intervention without crossover. Secondary feasibility outcomes were eligibility rate; recruitment proportion and rate; data completeness; and rate of clinician refusal.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We screened 480 patients and 206 (43%) were eligible; 150\/203 (74%) approached provided informed consent. Three of 206 (1%) eligible patients were not included due to clinician refusal. Of 149 patients who were randomised, 76 were assigned to the pulmonary artery catheter group and 73 to the central venous catheter group. For the primary feasibility outcome, 147 patients (99%) received the allocated intervention. Data were complete for 144 (97%) patients. Median (IQR [range]) days alive and at home at 30\u2009days was 23.7 (21.9\u201324.7 [7.0\u201326.0]) in the pulmonary artery catheter group and 22.9 (20.8\u201323.9 [8.6\u201325.8]) in the central venous catheter group. Acute kidney injury occurred in 26\/76 (34%) patients in the pulmonary artery catheter group and 14\/73 (19%) in the central venous catheter group.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>A randomised trial of pulmonary artery catheters compared with central venous catheters in low\u2010risk cardiac surgery is feasible. Such a trial would address significant practice variability and inform international guidelines.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/anae.70282","type":"journal-article","created":{"date-parts":[[2026,6,29]],"date-time":"2026-06-29T02:20:31Z","timestamp":1782699631000},"page":"1358-1366","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Pulmonary artery catheters or central venous catheters for cardiac surgery: the\n                    <scp>PUMA<\/scp>\n                    Pilot randomised clinical trial"],"prefix":"10.1111","volume":"81","author":[{"given":"Luke A.","family":"Perry","sequence":"first","affiliation":[{"name":"Victorian Cardiac Anaesthesia Research Laboratory, Department of Surgery, School of Clinical Sciences Monash University  Melbourne VIC Australia"},{"name":"Department of Anaesthesia and Perioperative Medicine Victorian Heart Hospital  Melbourne VIC Australia"},{"name":"Department of Critical Care, Melbourne Medical School The University of Melbourne  Melbourne VIC Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reny","family":"Segal","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Pain Management Royal Melbourne Hospital  Melbourne VIC Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Larobina","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery Victorian Heart Hospital, Monash Health  Melbourne VIC Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rinaldo","family":"Bellomo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julian A.","family":"Smith","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery Victorian Heart Hospital, Monash Health  Melbourne VIC Australia"},{"name":"Department of Surgery, School of Clinical Sciences at Monash Health Monash University  Melbourne VIC Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jesselyn","family":"Sin","sequence":"additional","affiliation":[{"name":"Victorian Cardiac Anaesthesia Research Laboratory, Department of Surgery, School of Clinical Sciences Monash University  Melbourne VIC Australia"},{"name":"Department of Anaesthesia and Perioperative Medicine Victorian Heart Hospital  Melbourne VIC Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katrina","family":"Danial","sequence":"additional","affiliation":[{"name":"Victorian Cardiac Anaesthesia Research Laboratory, Department of Surgery, School of Clinical Sciences Monash University  Melbourne VIC Australia"},{"name":"Department of Anaesthesia and Perioperative Medicine Victorian Heart Hospital  Melbourne VIC Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alistair R. D.","family":"McLean","sequence":"additional","affiliation":[{"name":"Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health The University of Melbourne  Melbourne VIC Australia"},{"name":"MISCH (Methods and Implementation Support for Clinical Health) Research Hub, Faculty of Medicine, Dentistry and Health Sciences The University of Melbourne  Melbourne VIC Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisa Q.","family":"Rong","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology Weill Cornell Medicine  New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Gaudino","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery Weill Cornell Medicine New York NY USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Schwann","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery Corewell Health  Royal Oak MI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie","family":"Palumbo","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Perioperative Medicine Victorian Heart Hospital  Melbourne VIC Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luke","family":"O'Halloran","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Perioperative Medicine Victorian Heart Hospital  Melbourne VIC Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Chee","sequence":"additional","affiliation":[{"name":"Victorian Cardiac Anaesthesia Research Laboratory, Department of Surgery, School of Clinical Sciences Monash University  Melbourne VIC Australia"},{"name":"Department of Anaesthesia and Perioperative Medicine Victorian Heart Hospital  Melbourne VIC Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinesh","family":"Patel","sequence":"additional","affiliation":[{"name":"Victorian Cardiac Anaesthesia Research Laboratory, Department of Surgery, School of Clinical Sciences Monash University  Melbourne VIC Australia"},{"name":"Department of Anaesthesia and Perioperative Medicine Victorian Heart Hospital  Melbourne VIC Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Silvers","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia and Perioperative Medicine Victorian Heart Hospital  Melbourne VIC Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayme","family":"Bennetts","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery Victorian Heart Hospital, Monash Health  Melbourne VIC Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvana","family":"Marasco","sequence":"additional","affiliation":[{"name":"Department of Surgery, School of Clinical Sciences at Monash Health Monash University  Melbourne VIC Australia"},{"name":"Cardiothoracic Unit The Alfred  Melbourne VIC Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tim G.","family":"Coulson","sequence":"additional","affiliation":[{"name":"Department of Critical Care, Melbourne Medical School The University of Melbourne  Melbourne VIC Australia"},{"name":"Department of Anaesthesiology and Perioperative Medicine Alfred Health  Melbourne VIC Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alistair","family":"Royse","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery Royal Melbourne Hospital  Melbourne VIC Australia"},{"name":"Department of Surgery The University of Melbourne  Melbourne VIC Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"See","sequence":"additional","affiliation":[{"name":"Department of Critical Care, Melbourne Medical School The University of Melbourne  Melbourne VIC Australia"},{"name":"Departments of Intensive Care and Nephrology The Royal Melbourne Hospital  Melbourne VIC Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lachlan F.","family":"Miles","sequence":"additional","affiliation":[{"name":"Department of Critical Care, Melbourne Medical School The University of Melbourne  Melbourne VIC Australia"},{"name":"Department of Anaesthesia Austin Health  Melbourne VIC Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"the ANZCA Clinical Trials Network","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,6,28]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003408.pub3"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.276.11.889"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa021108"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140\u20106736(05)67061\u20104"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.286.3.348"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1996.03540110070035"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2017.1670"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.298.4.423"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/icvts\/ivae129"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1177\/145749690909800402"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1985.03350300079024"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/2110\u20105820\u20103\u201038"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.121.6.2009"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1164\/arrd.1982.126.6.1001"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1213\/ane.0b013e3181ff475e"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2024.10.008"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2023.12.006"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542\u2010200310000\u201000036"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2025.01.015"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2014.07.016"},{"key":"e_1_2_6_22_1","article-title":"Trends in pulmonary artery catheter use for cardiac surgery, 2013\u20132023: analysis of Australian medicare data","volume":"27","author":"Perry LA","year":"2025","journal-title":"Crit Care Resusc"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2025.08.047"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2020.08.043"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1186\/1741\u20107015\u20108\u201018"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.i5239"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezs043"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1159\/000339789"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/0168\u20108510(90)90421\u20109"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e31822c94a8"},{"key":"e_1_2_6_31_1","first-page":"32","article-title":"Comparative study of pulmonary artery catheter versus central venous catheter in patients undergoing beating heart coronary artery bypass surgery","volume":"2","author":"Desai PM","year":"2015","journal-title":"Indian J Clin Anaesth"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2015.56.4.913"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/821218"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.1177\/0310057x1804600103"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1814052"},{"key":"e_1_2_6_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2018.03.002"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2025.03.011"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2023.06.006"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2025.08.013"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1161\/jaha.120.020513"}],"container-title":["Anaesthesia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/associationofanaesthetists-publications.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/anae.70282","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/associationofanaesthetists-publications.onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/anae.70282","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/associationofanaesthetists-publications.onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/anae.70282","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T08:33:30Z","timestamp":1788856410000},"score":1,"resource":{"primary":{"URL":"https:\/\/associationofanaesthetists-publications.onlinelibrary.wiley.com\/doi\/10.1111\/anae.70282"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,28]]},"references-count":39,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1111\/anae.70282"],"URL":"https:\/\/doi.org\/10.1111\/anae.70282","archive":["Portico"],"relation":{},"ISSN":["0003-2409","1365-2044"],"issn-type":[{"value":"0003-2409","type":"print"},{"value":"1365-2044","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,6,28]]},"assertion":[{"value":"2026-05-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-28","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}