{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:51:48Z","timestamp":1791334308916,"version":"4.3.1"},"reference-count":13,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:00:00Z","timestamp":1791244800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T00:00:00Z","timestamp":1791244800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100011955","name":"European Society of Regional Anaesthesia and Pain Therapy","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011955","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["associationofanaesthetists-publications.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Anaesthesia"],"abstract":"<jats:title>Summary<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Infiltration between the popliteal artery and the capsule of the knee (IPACK) and the selective tibial nerve block both provide analgesia for the posterior aspect of the knee after anterior cruciate ligament reconstruction. This randomised controlled triple\u2010blinded trial tested the hypothesis that IPACK provides superior analgesia to a selective tibial nerve block after anterior cruciate ligament reconstruction.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Eighty patients having anterior cruciate ligament reconstruction under general anaesthesia with a femoral triangle block were allocated randomly to receive either IPACK with 20\u2009ml ropivacaine 0.2% or a selective tibial nerve block with 5\u2009ml ropivacaine 0.75%. Postoperative analgesia included paracetamol, ibuprofen and intravenous morphine patient\u2010controlled analgesia. Primary outcome was cumulative postoperative intravenous morphine consumption at 24\u2009h. Secondary pain\u2010related outcomes included pain scores at rest and on movement at 2\u2009h, 24\u2009h and 48 h. Early functional outcomes evaluated were range of motion; quadriceps strength; and walking distance measured at 24\u2009h and 48\u2009h. Late functional outcomes included concentric quadriceps strength and single\u2010hop test, measured at 4\u2009months and 8\u2009months.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Median (IQR [range]) cumulative intravenous morphine consumption at 24\u2009h postoperatively was similar between IPACK (12 (6\u201320 [0\u201354]) mg) and selective tibial nerve block (16 (10\u201330 [0\u201366]) mg, p\u2009=\u20090.073). No significant differences between groups were seen in the secondary pain or functional outcomes. No complications were reported.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>The IPACK and selective tibial nerve block provide comparable postoperative analgesia after anterior cruciate ligament reconstruction under general anaesthesia with a femoral triangle block, with similar impact on functional outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/anae.70433","type":"journal-article","created":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T00:10:16Z","timestamp":1791331816000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Infiltration between the popliteal artery and the capsule of the knee (\n                    <scp>IPACK<\/scp>\n                    ) vs. selective tibial nerve block for analgesia after anterior cruciate ligament reconstruction: a\u00a0randomised controlled trial"],"prefix":"10.1111","author":[{"given":"Ludovic","family":"Beun","sequence":"first","affiliation":[{"name":"Department of Anaesthesia Lausanne University Hospital  Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin","family":"Martin","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics Lausanne University Hospital  Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trieu Hoai Nam","family":"Ngo","sequence":"additional","affiliation":[{"name":"Department of Orthopaedics Lausanne University Hospital  Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Benoit","family":"Rossel","sequence":"additional","affiliation":[{"name":"Department of Clinical Research, Centre for Primary Care and Public Health (Unisant\u00e9) Lausanne University Hospital  Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthieu","family":"Andr\u00e9","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia Lausanne University Hospital  Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6432-1311","authenticated-orcid":false,"given":"Eric","family":"Albrecht","sequence":"additional","affiliation":[{"name":"Department of Anaesthesia Lausanne University Hospital  Lausanne Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,6]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/anae.14032"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0363546516669715"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2019.04.053"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1136\/rapm\u20102021\u2010102631"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/ALN.0b013e318279fa0b"},{"key":"e_1_2_6_7_1","first-page":"233","article-title":"Novel regional techniques for total knee arthroplasty promote reduced hospital length of stay: an analysis of 106 patients","volume":"17","author":"Thobhani S","year":"2017","journal-title":"Ochsner 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