{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T03:19:44Z","timestamp":1762917584796},"reference-count":21,"publisher":"Hindawi Limited","issue":"3","license":[{"start":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T00:00:00Z","timestamp":1441065600000},"content-version":"tdm","delay-in-days":99,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Andrologia"],"published-print":{"date-parts":[[2016,4]]},"DOI":"10.1111\/and.12441","type":"journal-article","created":{"date-parts":[[2015,5,25]],"date-time":"2015-05-25T15:06:06Z","timestamp":1432566366000},"page":"262-267","source":"Crossref","is-referenced-by-count":5,"title":["Effect of DDAH\/ADMA\/NOS regulation pathway on cavernae corporum cavernosorum rat penis of different age"],"prefix":"10.1155","volume":"48","author":[{"given":"J.-H.","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Urology; Shandong Provincial Hospital Affiliated to Shandong University; Jinan Shandong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Urology; Shandong Provincial Hospital Affiliated to Shandong University; Jinan Shandong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.-Q.","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Urology; Shandong Provincial Hospital Affiliated to Shandong University; Jinan Shandong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Urology; Shandong Provincial Hospital Affiliated to Shandong University; Jinan Shandong China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Q.","family":"Fu","sequence":"additional","affiliation":[{"name":"Department of Urology; Shandong Provincial Hospital Affiliated to Shandong University; Jinan Shandong China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","published-online":{"date-parts":[[2015,5,25]]},"reference":[{"key":"10.1111\/and.12441-BIB0001|and12441-cit-0001","doi-asserted-by":"crossref","first-page":"e9462","DOI":"10.1371\/journal.pone.0009462","article-title":"Sequence variation in DDAH1 and DDAH2 genes is strongly and additively associated with serum ADMA concentrations in individuals with type 2 diabetes","volume":"5","author":"Abhary","year":"2010","journal-title":"PLoS One"},{"key":"10.1111\/and.12441-BIB0002|and12441-cit-0002","doi-asserted-by":"crossref","first-page":"168","DOI":"10.5114\/aoms.2010.13888","article-title":"Asymmetrical dimethylarginine and severity of erectile dysfunction and their impact on cardiovascular events in patients with acute coronary syndrome","volume":"6","author":"Aktoz","year":"2010","journal-title":"Arch Med Sci"},{"key":"10.1111\/and.12441-BIB0003|and12441-cit-0003","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1111\/j.1442-2042.2009.02426.x","article-title":"Endothelial dysfunction and erectile dysfunction in the aging man","volume":"17","author":"Aversa","year":"2010","journal-title":"Int J Urol"},{"key":"10.1111\/and.12441-BIB0004|and12441-cit-0004","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1007\/BF02550501","article-title":"Ultrastructual changes of corpora cavernosa in vascular erectile dysfunction","volume":"28","author":"Aydos","year":"1996","journal-title":"Int Urol Nephrol"},{"key":"10.1111\/and.12441-BIB0005|and12441-cit-0005","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1177\/0003319713513145","article-title":"Asymmetric dimethylarginine and augmentation index in newly diagnosed patients with hypertension","volume":"66","author":"Cakar","year":"2015","journal-title":"Angiology"},{"key":"10.1111\/and.12441-BIB0006|and12441-cit-0006","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1111\/j.1464-410X.2009.08852.x","article-title":"Abnormal protein expression in the corpus cavernosum impairs erectile function in type 2 diabetes","volume":"105","author":"Chiou","year":"2010","journal-title":"BJU Int"},{"key":"10.1111\/and.12441-BIB0007|and12441-cit-0007","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/j.purol.2013.01.010","article-title":"Erectile dysfunction","volume":"23","author":"Giuliano","year":"2013","journal-title":"Prog Urol"},{"key":"10.1111\/and.12441-BIB0008|and12441-cit-0008","doi-asserted-by":"crossref","first-page":"136","DOI":"10.7861\/clinmedicine.13-2-136","article-title":"Erectile dysfunction in general medicine","volume":"13","author":"Grant","year":"2013","journal-title":"Clin Med"},{"key":"10.1111\/and.12441-BIB0009|and12441-cit-0009","doi-asserted-by":"crossref","first-page":"3373","DOI":"10.1111\/j.1743-6109.2010.01920.x","article-title":"Morphological and functional evidence for the contribution of the pudendal artery in aging-induced erectile dysfunction","volume":"7","author":"Hannan","year":"2010","journal-title":"J Sex Med"},{"key":"10.1111\/and.12441-BIB0010|and12441-cit-0010","doi-asserted-by":"crossref","first-page":"R2081","DOI":"10.1152\/ajpregu.00406.2007","article-title":"Alterations of NOS, arginase, and DDAH protein expression in rabbit cavernous tissue after administration of cigarette smoke extract","volume":"293","author":"Imamura","year":"2007","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1111\/and.12441-BIB0011|and12441-cit-0011","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1002\/path.4127","article-title":"The role of dimethylarginine dimethylaminohydrolase (DDAH) in pulmonary fibrosis","volume":"229","author":"Janssen","year":"2013","journal-title":"J Pathol"},{"key":"10.1111\/and.12441-BIB0012|and12441-cit-0012","doi-asserted-by":"crossref","first-page":"2206","DOI":"10.1111\/j.1743-6109.2009.01310.x","article-title":"Ultrastructural changes of penile cavernous tissue in multiple sclerotic rats","volume":"6","author":"Jiang","year":"2009","journal-title":"J Sex Med"},{"key":"10.1111\/and.12441-BIB0013|and12441-cit-0013","doi-asserted-by":"crossref","first-page":"L984","DOI":"10.1152\/ajplung.00224.2003","article-title":"Nitric oxide decreases endothelin-1 secretion through the activation of soluble guanylate cyclase","volume":"286","author":"Kelly","year":"2004","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10.1111\/and.12441-BIB0014|and12441-cit-0014","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1164\/rccm.201304-0686PP","article-title":"Nitric oxide deficiency and endothelial dysfunction in pulmonary arterial hypertension","volume":"188","author":"Klinger","year":"2013","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1111\/and.12441-BIB0115|and12441-cit-0115","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/S0008-6363(99)00162-5","article-title":"Biological significance of endogenous methylarginines that inhibit nitric oxide synthases","volume":"43","author":"Leiper","year":"1999","journal-title":"Cardiovascular research"},{"key":"10.1111\/and.12441-BIB0015|and12441-cit-0015","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1152\/ajpregu.00277.2001","article-title":"Accumulated endogenous NOS inhibitors, decreased NOS activity, and impaired cavernosal relaxation with ischemia","volume":"282","author":"Masuda","year":"2002","journal-title":"Am J Physiol Regul Integr Comp Physiol"},{"key":"10.1111\/and.12441-BIB0016|and12441-cit-0016","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1038\/ijir.2009.20","article-title":"Dimethylarginine dimethylaminohydrolase in rat penile tissue: reduced enzyme activity is responsible for erectile dysfunction in a rat model of atherosclerosis","volume":"21","author":"Park","year":"2009","journal-title":"Int J Impot Res"},{"key":"10.1111\/and.12441-BIB0017|and12441-cit-0017","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1056\/NEJM199901143400207","article-title":"Atherosclerosis: an inflammatory disease","volume":"340","author":"Ross","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1111\/and.12441-BIB0018|and12441-cit-0018","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1161\/HYPERTENSIONAHA.108.114207","article-title":"Nitric oxide upregulates dimethylarginine dimethylaminohydrolase-2 via cyclic GMP induction in endothelial cells","volume":"52","author":"Sakurada","year":"2008","journal-title":"Hypertension"},{"key":"10.1111\/and.12441-BIB0019|and12441-cit-0019","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1111\/j.1365-2605.2010.01083.x","article-title":"Dietary antioxidants improve arteriogenic erectile dysfunction","volume":"34","author":"Zhang","year":"2011","journal-title":"Int J Androl"},{"key":"10.1111\/and.12441-BIB0020|and12441-cit-0020","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1111\/j.1743-6109.2009.01300.x","article-title":"Metrics for evaluation of age-related changes in erectile capacity in a rodent model","volume":"6","author":"Zhao","year":"2009","journal-title":"J Sex Med"}],"container-title":["Andrologia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fand.12441","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/and.12441\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T12:37:04Z","timestamp":1671539824000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/and.12441"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,5,25]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,4]]}},"URL":"https:\/\/doi.org\/10.1111\/and.12441","archive":["Portico"],"relation":{},"ISSN":["0303-4569"],"issn-type":[{"value":"0303-4569","type":"print"}],"subject":[],"published":{"date-parts":[[2015,5,25]]}}}