{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T16:23:55Z","timestamp":1776356635858,"version":"3.51.2"},"reference-count":71,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,12,4]],"date-time":"2017-12-04T00:00:00Z","timestamp":1512345600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2017,12,4]],"date-time":"2017-12-04T00:00:00Z","timestamp":1512345600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"American Center for Reproductive Medicine, Cleveland Clinic, USA"},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["FAPESP, grant# 2015\/18867-6"],"award-info":[{"award-number":["FAPESP, grant# 2015\/18867-6"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Andrologia"],"published-print":{"date-parts":[[2018,4]]},"DOI":"10.1111\/and.12919","type":"journal-article","created":{"date-parts":[[2017,12,5]],"date-time":"2017-12-05T10:27:31Z","timestamp":1512469651000},"page":"e12919","source":"Crossref","is-referenced-by-count":57,"title":["Towards the identification of reliable sperm biomarkers for male infertility: A sperm proteomic approach"],"prefix":"10.1155","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8494-6009","authenticated-orcid":false,"given":"P.","family":"Intasqui","sequence":"first","affiliation":[{"name":"American Center for Reproductive Medicine; Cleveland Clinic; Cleveland OH USA"},{"name":"Department of Surgery; Division of Urology; Human Reproduction Section; Sao Paulo Federal University - Sao Paulo Hospital; Sao Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0585-1026","authenticated-orcid":false,"given":"A.","family":"Agarwal","sequence":"additional","affiliation":[{"name":"American Center for Reproductive Medicine; Cleveland Clinic; Cleveland OH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9664-6978","authenticated-orcid":false,"given":"R.","family":"Sharma","sequence":"additional","affiliation":[{"name":"American Center for Reproductive Medicine; Cleveland Clinic; Cleveland OH USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2969-0071","authenticated-orcid":false,"given":"L.","family":"Samanta","sequence":"additional","affiliation":[{"name":"Department of Zoology; Ravenshaw University; Cuttack India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6892-9244","authenticated-orcid":false,"given":"R. P.","family":"Bertolla","sequence":"additional","affiliation":[{"name":"Department of Surgery; Division of Urology; Human Reproduction Section; Sao Paulo Federal University - Sao Paulo Hospital; Sao Paulo Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2017,12,4]]},"reference":[{"issue":"Suppl 1","key":"10.1111\/and.12919-BIB0001|and12919-cit-0001","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1111\/j.1439-0272.2010.01156.x","article-title":"Sequential analysis of sperm functional aspects involved in fertilisation: A pilot study","volume":"44","author":"Abu","year":"2012","journal-title":"Andrologia"},{"key":"10.1111\/and.12919-BIB0002|and12919-cit-0002","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/s12958-015-0007-2","article-title":"Major protein alterations in spermatozoa from infertile men with unilateral varicocele","volume":"13","author":"Agarwal","year":"2015","journal-title":"Reproductive Biology and Endocrinology"},{"key":"10.1111\/and.12919-BIB0003|and12919-cit-0003","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1016\/j.urology.2014.11.030","article-title":"Differential proteomic profiling of spermatozoal proteins of infertile men with unilateral or bilateral varicocele","volume":"85","author":"Agarwal","year":"2015","journal-title":"Urology"},{"key":"10.1111\/and.12919-BIB0004|and12919-cit-0004","doi-asserted-by":"crossref","first-page":"43","DOI":"10.4103\/1008-682X.153848","article-title":"Spermatozoa protein alterations in infertile men with bilateral varicocele","volume":"18","author":"Agarwal","year":"2016","journal-title":"Asian Journal of Andrology"},{"key":"10.1111\/and.12919-BIB0005|and12919-cit-0005","doi-asserted-by":"crossref","first-page":"282","DOI":"10.4103\/1008-682X.170445","article-title":"Proteomic signatures of infertile men with clinical varicocele and their validation studies reveal mitochondrial dysfunction leading to infertility","volume":"18","author":"Agarwal","year":"2016","journal-title":"Asian Journal of Andrology"},{"key":"10.1111\/and.12919-BIB0006|and12919-cit-0006","doi-asserted-by":"crossref","first-page":"5670","DOI":"10.1021\/pr500652y","article-title":"Identification of proteins involved in human sperm motility using high-throughput differential proteomics","volume":"13","author":"Amaral","year":"2014","journal-title":"Journal of Proteome Research"},{"key":"10.1111\/and.12919-BIB0007|and12919-cit-0007","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.7150\/ijms.6395","article-title":"Mammalian sperm fertility related proteins","volume":"10","author":"Ashrafzadeh","year":"2013","journal-title":"International Journal of Medical Sciences"},{"key":"10.1111\/and.12919-BIB0008|and12919-cit-0008","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/1559-0275-12-4","article-title":"Impact of precise modulation of reactive oxygen species levels on spermatozoa proteins in infertile men","volume":"12","author":"Ayaz","year":"2015","journal-title":"Clinical Proteomics"},{"key":"10.1111\/and.12919-BIB0009|and12919-cit-0009","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1530\/rep.0.1260183","article-title":"Involvement of tyrosine kinase and cAMP-dependent kinase cross-talk in the regulation of human sperm motility","volume":"126","author":"Bajpai","year":"2003","journal-title":"Reproduction"},{"key":"10.1111\/and.12919-BIB0010|and12919-cit-0010","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/s00441-015-2249-x","article-title":"Proteomics of post-translational modifications of mammalian spermatozoa","volume":"363","author":"Baker","year":"2016","journal-title":"Cell and Tissue Research"},{"key":"10.1111\/and.12919-BIB0011|and12919-cit-0011","doi-asserted-by":"crossref","first-page":"5252","DOI":"10.1021\/pr300468m","article-title":"Analysis of phosphopeptide changes as spermatozoa acquire functional competence in the epididymis demonstrates changes in the post-translational modification of Izumo1","volume":"11","author":"Baker","year":"2012","journal-title":"Journal of Proteome Research"},{"key":"10.1111\/and.12919-BIB0012|and12919-cit-0012","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1093\/molehr\/gau073","article-title":"Evidence for the involvement of proline-rich tyrosine kinase 2 in tyrosine phosphorylation downstream of protein kinase A activation during human sperm capacitation","volume":"20","author":"Battistone","year":"2014","journal-title":"Molecular Human Reproduction"},{"key":"10.1111\/and.12919-BIB0013|and12919-cit-0013","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1126\/science.2188360","article-title":"Interaction of Hsp 70 with newly synthesized proteins: Implications for protein folding and assembly","volume":"248","author":"Beckmann","year":"1990","journal-title":"Science"},{"key":"10.1111\/and.12919-BIB0014|and12919-cit-0014","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1093\/molehr\/gav041","article-title":"Novel characterization of the HSPA2-stabilizing protein BAG6 in human spermatozoa","volume":"21","author":"Bromfield","year":"2015","journal-title":"Molecular Human Reproduction"},{"key":"10.1111\/and.12919-BIB0015|and12919-cit-0015","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/S0025-7125(03)00150-0","article-title":"Male factor infertility: Evaluation and management","volume":"88","author":"Brugh","year":"2004","journal-title":"The Medical Clinics of North America"},{"key":"10.1111\/and.12919-BIB0016|and12919-cit-0016","doi-asserted-by":"crossref","first-page":"17332","DOI":"10.1074\/jbc.M011252200","article-title":"Identification of sperm-specific proteins that interact with A-kinase anchoring proteins in a manner similar to the type II regulatory subunit of PKA","volume":"276","author":"Carr","year":"2001","journal-title":"The Journal of Biological Chemistry"},{"key":"10.1111\/and.12919-BIB0017|and12919-cit-0017","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1093\/humrep\/del055","article-title":"Oligozoospermia and heat-shock protein expression in ejaculated spermatozoa","volume":"21","author":"Cedenho","year":"2006","journal-title":"Human Reproduction"},{"key":"10.1111\/and.12919-BIB0018|and12919-cit-0018","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1093\/abbs\/gmv045","article-title":"Alteration of sperm protein profile induced by cigarette smoking","volume":"47","author":"Chen","year":"2015","journal-title":"Acta Biochimica et Biophysica Sinica"},{"key":"10.1111\/and.12919-BIB0019|and12919-cit-0019","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1038\/332805a0","article-title":"70K heat shock related proteins stimulate protein translocation into microsomes","volume":"332","author":"Chirico","year":"1988","journal-title":"Nature"},{"key":"10.1111\/and.12919-BIB0020|and12919-cit-0020","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1186\/1479-5876-7-61","article-title":"Sperm protein 17 is expressed in the sperm fibrous sheath","volume":"7","author":"Chiriva-Internati","year":"2009","journal-title":"Journal of Translational Medicine"},{"key":"10.1111\/and.12919-BIB0021|and12919-cit-0021","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/S0962-8924(99)01558-5","article-title":"AKAPs: From structure to function","volume":"9","author":"Colledge","year":"1999","journal-title":"Trends in Cell Biology"},{"key":"10.1111\/and.12919-BIB0022|and12919-cit-0022","doi-asserted-by":"crossref","first-page":"3264","DOI":"10.1073\/pnas.93.8.3264","article-title":"Targeted gene disruption of Hsp70-2 results in failed meiosis, germ cell apoptosis, and male infertility","volume":"93","author":"Dix","year":"1996","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"key":"10.1111\/and.12919-BIB0023|and12919-cit-0023","doi-asserted-by":"crossref","first-page":"4595","DOI":"10.1242\/dev.124.22.4595","article-title":"HSP70-2 is required for desynapsis of synaptonemal complexes during meiotic prophase in juvenile and adult mouse spermatocytes","volume":"124","author":"Dix","year":"1997","journal-title":"Development"},{"key":"10.1111\/and.12919-BIB0024|and12919-cit-0024","doi-asserted-by":"crossref","first-page":"11579","DOI":"10.1074\/jbc.M202325200","article-title":"Phosphoproteome analysis of capacitated human sperm. Evidence of tyrosine phosphorylation of a kinase-anchoring protein 3 and valosin-containing protein\/p97 during capacitation","volume":"278","author":"Ficarro","year":"2003","journal-title":"The Journal of Biological Chemistry"},{"key":"10.1111\/and.12919-BIB0025|and12919-cit-0025","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.fertnstert.2014.04.039","article-title":"Proteomic identification of target proteins in normal but nonfertilizing sperm","volume":"102","author":"Frapsauce","year":"2014","journal-title":"Fertility and Sterility"},{"key":"10.1111\/and.12919-BIB0026|and12919-cit-0026","doi-asserted-by":"crossref","first-page":"2199","DOI":"10.1007\/s13361-011-0237-2","article-title":"Evaluation of normalization methods on GeLC-MS\/MS label-free spectral counting data to correct for variation during proteomic workflows","volume":"22","author":"Gokce","year":"2011","journal-title":"Journal of the American Society for Mass Spectrometry"},{"key":"10.1111\/and.12919-BIB0027|and12919-cit-0027","doi-asserted-by":"crossref","first-page":"37888","DOI":"10.1074\/jbc.M608147200","article-title":"Post-meiotic shifts in HSPA2\/HSP70.2 chaperone activity during mouse spermatogenesis","volume":"281","author":"Govin","year":"2006","journal-title":"The Journal of Biological Chemistry"},{"key":"10.1111\/and.12919-BIB0028|and12919-cit-0028","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1177\/002215540305100916","article-title":"Immunolocalization of sperm protein 17 in human testis and ejaculated spermatozoa","volume":"51","author":"Grizzi","year":"2003","journal-title":"Journal of Histochemistry and Cytochemistry"},{"key":"10.1111\/and.12919-BIB0029|and12919-cit-0029","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1007\/s10815-015-0465-7","article-title":"A proteomic analysis on human sperm tail: Comparison between normozoospermia and asthenozoospermia","volume":"32","author":"Hashemitabar","year":"2015","journal-title":"Journal of Assisted Reproduction and Genetics"},{"key":"10.1111\/and.12919-BIB0030|and12919-cit-0030","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.fertnstert.2003.06.027","article-title":"Negative lifestyle is associated with a significant reduction in fecundity","volume":"81","author":"Hassan","year":"2004","journal-title":"Fertility and Sterility"},{"key":"10.1111\/and.12919-BIB0031|and12919-cit-0031","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/j.urology.2012.06.027","article-title":"Study of sperm protein profile in men with and without varicocele using two-dimensional gel electrophoresis","volume":"81","author":"Hosseinifar","year":"2013","journal-title":"Urology"},{"issue":"Suppl 3","key":"10.1111\/and.12919-BIB0032|and12919-cit-0032","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1016\/S0015-0282(03)00402-3","article-title":"Hyaluronic acid binding by human sperm indicates cellular maturity, viability, and unreacted acrosomal status","volume":"79","author":"Huszar","year":"2003","journal-title":"Fertility and Sterility"},{"key":"10.1111\/and.12919-BIB0033|and12919-cit-0033","doi-asserted-by":"crossref","first-page":"925","DOI":"10.1095\/biolreprod63.3.925","article-title":"Putative creatine kinase M-isoform in human sperm is identified as the 70-kilodalton heat shock protein HspA2","volume":"63","author":"Huszar","year":"2000","journal-title":"Biology of Reproduction"},{"key":"10.1111\/and.12919-BIB0034|and12919-cit-0034","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1007\/s10815-013-0054-6","article-title":"Unraveling the sperm proteome and post-genomic pathways associated with sperm nuclear DNA fragmentation","volume":"30","author":"Intasqui","year":"2013","journal-title":"Journal of Assisted Reproduction and Genetics"},{"key":"10.1111\/and.12919-BIB0035|and12919-cit-0035","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/j.fertnstert.2004.03.056","article-title":"Body mass index in relation to semen quality and reproductive hormones among 1,558 Danish men","volume":"82","author":"Jensen","year":"2004","journal-title":"Fertility and Sterility"},{"key":"10.1111\/and.12919-BIB0036|and12919-cit-0036","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1093\/jb\/mvs149","article-title":"BAG6\/BAT3: Emerging roles in quality control for nascent polypeptides","volume":"153","author":"Kawahara","year":"2013","journal-title":"Journal of Biochemistry"},{"key":"10.1111\/and.12919-BIB0037|and12919-cit-0037","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1016\/j.fertnstert.2013.01.111","article-title":"The use of genomics, proteomics, and metabolomics in identifying biomarkers of male infertility","volume":"99","author":"Kovac","year":"2013","journal-title":"Fertility and Sterility"},{"key":"10.1111\/and.12919-BIB0038|and12919-cit-0038","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1016\/j.rbmo.2009.07.001","article-title":"Identification of diabetes- and obesity-associated proteomic changes in human spermatozoa by difference gel electrophoresis","volume":"19","author":"Kriegel","year":"2009","journal-title":"Reproductive Biomedicine Online"},{"key":"10.1111\/and.12919-BIB0039|and12919-cit-0039","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/0167-4781(96)00077-2","article-title":"Cloning and sequencing of cDNAs encoding the human sperm protein, Sp17","volume":"1307","author":"Lea","year":"1996","journal-title":"Biochimica et Biophysica Acta"},{"key":"10.1111\/and.12919-BIB0040|and12919-cit-0040","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1186\/1477-7827-2-57","article-title":"Association of sperm protein 17 with A-kinase anchoring protein 3 in flagella","volume":"2","author":"Lea","year":"2004","journal-title":"Reproductive Biology and Endocrinology"},{"key":"10.1111\/and.12919-BIB0041|and12919-cit-0041","doi-asserted-by":"crossref","first-page":"5403","DOI":"10.1021\/pr501031x","article-title":"Investigation of male infertility using quantitative comparative proteomics","volume":"13","author":"Legare","year":"2014","journal-title":"Journal of Proteome Research"},{"key":"10.1111\/and.12919-BIB0042|and12919-cit-0042","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1016\/j.fertnstert.2006.05.030","article-title":"Expression of the HSPA2 gene in ejaculated spermatozoa from adolescents with and without varicocele","volume":"86","author":"Lima","year":"2006","journal-title":"Fertility and Sterility"},{"key":"10.1111\/and.12919-BIB0043|and12919-cit-0043","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1111\/andr.289","article-title":"Proteomic pattern changes associated with obesity-induced asthenozoospermia","volume":"3","author":"Liu","year":"2015","journal-title":"Andrology"},{"key":"10.1111\/and.12919-BIB0044|and12919-cit-0044","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1093\/humrep\/den024","article-title":"Identification of proteomic differences in asthenozoospermic sperm samples","volume":"23","author":"Martinez-Heredia","year":"2008","journal-title":"Human Reproduction"},{"key":"10.1111\/and.12919-BIB0045|and12919-cit-0045","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1095\/biolreprod.111.098616","article-title":"Exposure to bleomycin, etoposide, and cis-platinum alters rat sperm chromatin integrity and sperm head protein profile","volume":"86","author":"Maselli","year":"2012","journal-title":"Biology of Reproduction"},{"key":"10.1111\/and.12919-BIB0046|and12919-cit-0046","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1095\/biolreprod.113.110759","article-title":"The effects of chemotherapy with bleomycin, etoposide, and cis-platinum (BEP) on rat sperm chromatin remodeling, fecundity and testicular gene expression in the progeny","volume":"89","author":"Maselli","year":"2013","journal-title":"Biology of Reproduction"},{"key":"10.1111\/and.12919-BIB0047|and12919-cit-0047","doi-asserted-by":"crossref","first-page":"4264","DOI":"10.1002\/pmic.200700521","article-title":"Marked correlations in protein expression identified by proteomic analysis of human spermatozoa","volume":"7","author":"Mateo","year":"2007","journal-title":"Proteomics"},{"key":"10.1111\/and.12919-BIB0048|and12919-cit-0048","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/j.fertnstert.2014.05.021","article-title":"Toward the identification of a subset of unexplained infertility: A sperm proteomic approach","volume":"102","author":"McReynolds","year":"2014","journal-title":"Fertility and Sterility"},{"key":"10.1111\/and.12919-BIB0049|and12919-cit-0049","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1016\/S0003-9993(99)90039-4","article-title":"Male infertility and erectile dysfunction in spinal cord injury: A review","volume":"80","author":"Monga","year":"1999","journal-title":"Archives of Physical Medicine and Rehabilitation"},{"key":"10.1111\/and.12919-BIB0050|and12919-cit-0050","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/0012-1606(88)90177-7","article-title":"Characterization of the rabbit sperm membrane autoantigen, RSA, as a lectin-like zona binding protein","volume":"129","author":"O'Rand","year":"1988","journal-title":"Developmental Biology"},{"key":"10.1111\/and.12919-BIB0051|and12919-cit-0051","doi-asserted-by":"crossref","first-page":"5861","DOI":"10.1016\/j.jprot.2012.07.003","article-title":"Sperm phosphoproteome profiling by ultra performance liquid chromatography followed by data independent analysis (LC-MS(E)) reveals altered proteomic signatures in asthenozoospermia","volume":"75","author":"Parte","year":"2012","journal-title":"Journal of Proteomics"},{"key":"10.1111\/and.12919-BIB0052|and12919-cit-0052","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.1093\/humrep\/deh224","article-title":"Sperm proteome mapping of a patient who experienced failed fertilization at IVF reveals altered expression of at least 20 proteins compared with fertile donors: Case report","volume":"19","author":"Pixton","year":"2004","journal-title":"Human Reproduction"},{"key":"10.1111\/and.12919-BIB0053|and12919-cit-0053","doi-asserted-by":"crossref","first-page":"360986","DOI":"10.1155\/2013\/360986","article-title":"Sperm proteomics: Road to male fertility and contraception","volume":"2013","author":"Rahman","year":"2013","journal-title":"International Journal of Endocrinology"},{"key":"10.1111\/and.12919-BIB0054|and12919-cit-0054","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1093\/molehr\/gas064","article-title":"Investigation of the mechanisms by which the molecular chaperone HSPA2 regulates the expression of sperm surface receptors involved in human sperm-oocyte recognition","volume":"19","author":"Redgrove","year":"2013","journal-title":"Molecular Human Reproduction"},{"key":"10.1111\/and.12919-BIB0055|and12919-cit-0055","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0050851","article-title":"The molecular chaperone HSPA2 plays a key role in regulating the expression of sperm surface receptors that mediate sperm-egg recognition","volume":"7","author":"Redgrove","year":"2012","journal-title":"PLoS ONE"},{"key":"10.1111\/and.12919-BIB0056|and12919-cit-0056","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1006\/dbio.1994.1285","article-title":"Sequence of a rabbit sperm zona pellucida binding protein and localization during the acrosome reaction","volume":"165","author":"Richardson","year":"1994","journal-title":"Developmental Biology"},{"key":"10.1111\/and.12919-BIB0057|and12919-cit-0057","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1083\/jcb.200802113","article-title":"Bat3 deficiency accelerates the degradation of Hsp70-2\/HspA2 during spermatogenesis","volume":"182","author":"Sasaki","year":"2008","journal-title":"The Journal of Cell Biology"},{"key":"10.1111\/and.12919-BIB0058|and12919-cit-0058","doi-asserted-by":"crossref","first-page":"110","DOI":"10.4103\/0970-1591.78436","article-title":"Genetic and epigenetic factors: Role in male infertility","volume":"27","author":"Shamsi","year":"2011","journal-title":"Indian Journal of Urology: IJU: Journal of the Urological Society of India"},{"key":"10.1111\/and.12919-BIB0059|and12919-cit-0059","first-page":"675","article-title":"Comet assay: A prognostic tool for DNA integrity assessment in infertile men opting for assisted reproduction","volume":"131","author":"Shamsi","year":"2010","journal-title":"The Indian Journal of Medical Research"},{"key":"10.1111\/and.12919-BIB0060|and12919-cit-0060","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1186\/1477-7827-11-48","article-title":"Proteomic analysis of human spermatozoa proteins with oxidative stress","volume":"11","author":"Sharma","year":"2013","journal-title":"Reproductive Biology and Endocrinology"},{"key":"10.1111\/and.12919-BIB0061|and12919-cit-0061","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1007\/s00345-013-1023-5","article-title":"Comparative proteomic study between human normal motility sperm and idiopathic asthenozoospermia","volume":"31","author":"Shen","year":"2013","journal-title":"World Journal of Urology"},{"key":"10.1111\/and.12919-BIB0062|and12919-cit-0062","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1093\/molehr\/gaq009","article-title":"Proteomics-based study on asthenozoospermia: Differential expression of proteasome alpha complex","volume":"16","author":"Siva","year":"2010","journal-title":"Molecular Human Reproduction"},{"key":"10.1111\/and.12919-BIB0063|and12919-cit-0063","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.gep.2013.10.002","article-title":"Dynamic expression of combinatorial replication-dependent histone variant genes during mouse spermatogenesis","volume":"14","author":"Sun","year":"2014","journal-title":"Gene Expression Patterns"},{"key":"10.1111\/and.12919-BIB0064|and12919-cit-0064","doi-asserted-by":"crossref","first-page":"2745","DOI":"10.1016\/j.fertnstert.2011.03.112","article-title":"Evaluation of sperm proteins in infertile men: A proteomic approach","volume":"95","author":"Thacker","year":"2011","journal-title":"Fertility and Sterility"},{"key":"10.1111\/and.12919-BIB0065|and12919-cit-0065","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1016\/S0015-0282(16)55089-4","article-title":"The influence of varicocele on parameters of fertility in a large group of men presenting to infertility clinics. World Health Organization","volume":"57","author":"UniProt AC Q96A08","year":"1992","journal-title":"Fertility and Sterility"},{"key":"10.1111\/and.12919-BIB0066|and12919-cit-0066","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1242\/dmm.013474","article-title":"Mechanisms of protein-folding diseases at a glance","volume":"7","author":"Valastyan","year":"2014","journal-title":"Disease Models & Mechanisms"},{"key":"10.1111\/and.12919-BIB0067|and12919-cit-0067","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1242\/dev.121.4.1129","article-title":"Capacitation of mouse spermatozoa. I. Correlation between the capacitation state and protein tyrosine phosphorylation","volume":"121","author":"Visconti","year":"1995","journal-title":"Development"},{"key":"10.1111\/and.12919-BIB0068|and12919-cit-0068","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1006\/dbio.1998.9137","article-title":"Processing of the sperm protein Sp17 during the acrosome reaction and characterization as a calmodulin binding protein","volume":"206","author":"Wen","year":"1999","journal-title":"Developmental Biology"},{"key":"10.1111\/and.12919-BIB0069|and12919-cit-0069","volume-title":"WHO laboratory manual for the examination and processing of human semen","author":"World Health Organization","year":"2010"},{"key":"10.1111\/and.12919-BIB0070|and12919-cit-0070","doi-asserted-by":"crossref","first-page":"5426","DOI":"10.1016\/j.jprot.2012.06.021","article-title":"Proteomic characteristics of spermatozoa in normozoospermic patients with infertility","volume":"75","author":"Xu","year":"2012","journal-title":"Journal of Proteomics"},{"key":"10.1111\/and.12919-BIB0071|and12919-cit-0071","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/j.fertnstert.2006.06.057","article-title":"Identification of several proteins involved in regulation of sperm motility by proteomic analysis","volume":"87","author":"Zhao","year":"2007","journal-title":"Fertility and Sterility"}],"container-title":["Andrologia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fand.12919","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/and.12919\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T12:36:44Z","timestamp":1671539804000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/and.12919"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,12,4]]},"references-count":71,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,4]]}},"URL":"https:\/\/doi.org\/10.1111\/and.12919","archive":["Portico"],"relation":{},"ISSN":["0303-4569"],"issn-type":[{"value":"0303-4569","type":"print"}],"subject":[],"published":{"date-parts":[[2017,12,4]]}}}