{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T01:13:23Z","timestamp":1793236403510,"version":"4.5.0"},"reference-count":165,"publisher":"Wiley","issue":"11","license":[{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"},{"start":{"date-parts":[[2018,12,20]],"date-time":"2018-12-20T00:00:00Z","timestamp":1545264000000},"content-version":"vor","delay-in-days":19,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Andrologia"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1111\/and.13126","type":"journal-article","created":{"date-parts":[[2018,12,20]],"date-time":"2018-12-20T04:36:40Z","timestamp":1545280600000},"page":"e13126","source":"Crossref","is-referenced-by-count":295,"title":["Role of oxidative stress, infection and inflammation in male infertility"],"prefix":"10.1155","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0585-1026","authenticated-orcid":false,"given":"Ashok","family":"Agarwal","sequence":"first","affiliation":[{"name":"American Center for Reproductive Medicine; Cleveland Clinic; Cleveland Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohit","family":"Rana","sequence":"additional","affiliation":[{"name":"American Center for Reproductive Medicine; Cleveland Clinic; Cleveland Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily","family":"Qiu","sequence":"additional","affiliation":[{"name":"American Center for Reproductive Medicine; Cleveland Clinic; Cleveland Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hashem","family":"AlBunni","sequence":"additional","affiliation":[{"name":"American Center for Reproductive Medicine; Cleveland Clinic; Cleveland Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert D.","family":"Bui","sequence":"additional","affiliation":[{"name":"American Center for Reproductive Medicine; Cleveland Clinic; Cleveland Ohio"},{"name":"Ohio University Heritage College of Osteopathic Medicine; Athens Ohio"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1128-2982","authenticated-orcid":false,"given":"Ralf","family":"Henkel","sequence":"additional","affiliation":[{"name":"American Center for Reproductive Medicine; Cleveland Clinic; Cleveland Ohio"},{"name":"Department of Medical Biosciences; University of the Western Cape; Bellville South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2018,12,20]]},"reference":[{"issue":"4","key":"10.1111\/and.13126-BIB0001|and13126-cit-0001","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/j.diagmicrobio.2013.05.018","article-title":"Molecular detection of potential sexually transmitted pathogens in semen and urine specimens of infertile and fertile males","volume":"77","author":"Abusarah","year":"2013","journal-title":"Diagnostic Microbiology and Infectious Disease"},{"issue":"3","key":"10.1111\/and.13126-BIB0002|and13126-cit-0002","doi-asserted-by":"crossref","first-page":"199","DOI":"10.4103\/iju.IJU_9_17","article-title":"Laboratory tests for oxidative stress","volume":"33","author":"Agarwal","year":"2017","journal-title":"Indian Journal of Urology: IJU: Journal of the Urological Society of India"},{"issue":"4","key":"10.1111\/and.13126-BIB0003|and13126-cit-0003","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/S0015-0282(02)04948-8","article-title":"Role of reactive oxygen species in the pathophysiology of human reproduction","volume":"79","author":"Agarwal","year":"2003","journal-title":"Fertility and Sterility"},{"issue":"3","key":"10.1111\/and.13126-BIB0004|and13126-cit-0004","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.urology.2008.07.053","article-title":"Role of oxidative stress in pathogenesis of varicocele and infertility","volume":"73","author":"Agarwal","year":"2009","journal-title":"Urology"},{"key":"10.1111\/and.13126-BIB0005|and13126-cit-0005","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1007\/978-81-322-3604-7_11","volume-title":"Male infertility","author":"Ahmad","year":"2017"},{"issue":"10","key":"10.1111\/and.13126-BIB0006|and13126-cit-0006","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1002\/mrd.22871","article-title":"Reactive oxygen species as mediators of sperm capacitation and pathological damage","volume":"84","author":"Aitken","year":"2017","journal-title":"Molecular Reproduction and Development"},{"key":"10.1111\/and.13126-BIB0007|and13126-cit-0007","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1093\/oxfordjournals.humrep.a136165","article-title":"Seminal leukocytes: Passengers, terrorists or good samaritans?","volume":"10","author":"Aitken","year":"1995","journal-title":"Human Reproduction"},{"issue":"2","key":"10.1111\/and.13126-BIB0008|and13126-cit-0008","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1530\/jrf.0.0810459","article-title":"Cellular basis of defective sperm function and its association with the genesis of reactive oxygen species by human spermatozoa","volume":"81","author":"Aitken","year":"1987","journal-title":"Journal of Reproduction and Fertility"},{"issue":"2","key":"10.1111\/and.13126-BIB0009|and13126-cit-0009","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1071\/RD15325","article-title":"Causes and consequences of oxidative stress in spermatozoa","volume":"28","author":"Aitken","year":"2016","journal-title":"Reproduction, Fertility and Development"},{"issue":"1","key":"10.1111\/and.13126-BIB0010|and13126-cit-0010","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1530\/jrf.0.0980257","article-title":"Relationship between iron-catalysed lipid peroxidation potential and human sperm function","volume":"98","author":"Aitken","year":"1993","journal-title":"Journal of Reproduction and Fertility"},{"issue":"8","key":"10.1111\/and.13126-BIB0011|and13126-cit-0011","first-page":"878","article-title":"Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice","volume":"8","author":"Alexopoulou","year":"2002","journal-title":"NatureMedicine"},{"issue":"7","key":"10.1111\/and.13126-BIB0012|and13126-cit-0012","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1111\/j.1476-5381.2009.00447.x","article-title":"Nitrite, NO and hypoxic vasodilation","volume":"158","author":"Allen","year":"2009","journal-title":"British Journal of Pharmacology"},{"issue":"1","key":"10.1111\/and.13126-BIB4000|and13126-cit-4000","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.jri.2013.05.004","article-title":"Prostatitis and male infertility","volume":"100","author":"Alshahrani","year":"2013","journal-title":"Journal of reproductive immunology"},{"issue":"1","key":"10.1111\/and.13126-BIB4001|and13126-cit-4001","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1111\/j.1479-828X.2009.01119.x","article-title":"Lifestyle factors in people seeking infertility treatment-a review","volume":"50","author":"Anderson","year":"2010","journal-title":"Australian and New Zealand journal of obstetrics and gynaecology"},{"issue":"4","key":"10.1111\/and.13126-BIB0013|and13126-cit-0013","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1159\/000074089","article-title":"Ureaplasma urealyticum and Mycoplasma hominis in men attending for routine semen analysis","volume":"71","author":"Andrade-Rocha","year":"2003","journal-title":"Urologia Internationalis"},{"key":"10.1111\/and.13126-BIB0014|and13126-cit-0014","first-page":"129","volume-title":"Immunopharmacology of joints and connective tissue","author":"Arend","year":"1994"},{"issue":"3","key":"10.1111\/and.13126-BIB0015|and13126-cit-0015","first-page":"123","article-title":"Impact of inflammation on male reproductive tract","volume":"16","author":"Azenabor","year":"2015","journal-title":"Journal of Reproduction & Infertility"},{"issue":"3","key":"10.1111\/and.13126-BIB0016|and13126-cit-0016","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/j.fertnstert.2004.02.112","article-title":"Novel associations between specific sperm morphological defects and leukocytospermia","volume":"82","author":"Aziz","year":"2004","journal-title":"Fertility and Sterility"},{"issue":"1","key":"10.1111\/and.13126-BIB0017|and13126-cit-0017","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.ucl.2013.08.008","article-title":"Infectious, inflammatory, and immunologic conditions resulting in male infertility","volume":"41","author":"Bachir","year":"2014","journal-title":"Urologic Clinics of North America"},{"issue":"3","key":"10.1111\/and.13126-BIB0018|and13126-cit-0018","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1016\/j.fertnstert.2004.07.976","article-title":"Deletions in L-type calcium channel \u03b11 subunit testicular transcripts correlate with testicular cadmium and apoptosis in infertile men with varicoceles","volume":"83","author":"Benoff","year":"2005","journal-title":"Fertility and Sterility"},{"issue":"6","key":"10.1111\/and.13126-BIB0019|and13126-cit-0019","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1093\/cid\/ciu447","article-title":"Vertical transmission of hepatitis C virus: Systematic review and meta-analysis","volume":"59","author":"Benova","year":"2014","journal-title":"Clinical Infectious Diseases"},{"issue":"6","key":"10.1111\/and.13126-BIB0020|and13126-cit-0020","doi-asserted-by":"crossref","first-page":"2536","DOI":"10.1210\/jc.2009-2354","article-title":"Testosterone therapy in men with androgen deficiency syndromes: An Endocrine Society clinical practice guideline","volume":"95","author":"Bhasin","year":"2010","journal-title":"The Journal of Clinical Endocrinology & Metabolism"},{"issue":"6","key":"10.1111\/and.13126-BIB0021|and13126-cit-0021","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/j.tube.2015.06.002","article-title":"The implication of pro-inflammatory cytokines in the impaired production of gonadal androgens by patients with pulmonary tuberculosis","volume":"95","author":"Bini","year":"2015","journal-title":"Tuberculosis (Edinburgh)"},{"issue":"5","key":"10.1111\/and.13126-BIB0022|and13126-cit-0022","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1016\/j.fertnstert.2015.01.044","article-title":"Ability of Escherichia coli to produce hemolysis leads to a greater pathogenic effect on human sperm","volume":"103","author":"Boguen","year":"2015","journal-title":"Fertility and Sterility"},{"issue":"5428","key":"10.1111\/and.13126-BIB0023|and13126-cit-0023","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1126\/science.285.5428.732","article-title":"Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors","volume":"285","author":"Brightbill","year":"1999","journal-title":"Science"},{"issue":"4","key":"10.1111\/and.13126-BIB0024|and13126-cit-0024","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1038\/aja.2010.38","article-title":"Obesity: Modern man's fertility nemesis","volume":"12","author":"Cabler","year":"2010","journal-title":"Asian Journal of Andrology"},{"issue":"2","key":"10.1111\/and.13126-BIB0025|and13126-cit-0025","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1080\/014850101316901280","article-title":"Interleukin-6 (IL-6) in seminal plasma of infertile men, and lipid peroxidation of their sperm","volume":"47","author":"Camejo","year":"2001","journal-title":"Archives of Andrology"},{"issue":"4","key":"10.1111\/and.13126-BIB0026|and13126-cit-0026","doi-asserted-by":"crossref","first-page":"S2","DOI":"10.1097\/00007435-199904001-00002","article-title":"Estimates of the incidence and prevalence of sexually transmitted diseases in the United States","volume":"26","author":"Cates","year":"1999","journal-title":"Sexually Transmitted Diseases"},{"issue":"4","key":"10.1111\/and.13126-BIB0027|and13126-cit-0027","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1111\/cmi.12529","article-title":"Neisseria gonorrhoeae survives within and modulates apoptosis and inflammatory cytokine production of human macrophages","volume":"18","author":"Ch\u00e2teau","year":"2016","journal-title":"Cellular Microbiology"},{"issue":"7","key":"10.1111\/and.13126-BIB0028|and13126-cit-0028","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1001\/jamapsychiatry.2014.366","article-title":"The changing face of heroin use in the United States: A retrospective analysis of the past 50 years","volume":"71","author":"Cicero","year":"2014","journal-title":"JAMA Psychiatry"},{"issue":"4","key":"10.1111\/and.13126-BIB0029|and13126-cit-0029","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1016\/S0022-5347(17)39618-0","article-title":"Cigarettes, alcohol and marijuana are related to pyospermia in infertile men","volume":"144","author":"Close","year":"1990","journal-title":"The Journal of Urology"},{"issue":"21","key":"10.1111\/and.13126-BIB0030|and13126-cit-0030","doi-asserted-by":"crossref","first-page":"3870","DOI":"10.3923\/pjbs.2007.3870.3874","article-title":"Cigarette smoking and the risk of male infertility","volume":"10","author":"Colagar","year":"2007","journal-title":"Pakistan Journal of Biological Sciences"},{"issue":"2-3","key":"10.1111\/and.13126-BIB0031|and13126-cit-0031","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/j.1600-0897.1994.tb00853.x","article-title":"Cytokines in semen of normal men and of patients with andrological diseases","volume":"31","author":"Comhaire","year":"1994","journal-title":"American Journal of Reproductive Immunology"},{"issue":"5","key":"10.1111\/and.13126-BIB0032|and13126-cit-0032","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1093\/humupd\/5.5.393","article-title":"Mechanisms and effects of male genital tract infection on sperm quality and fertilizing potential: The andrologist's viewpoint","volume":"5","author":"Comhaire","year":"1999","journal-title":"Human Reproduction Update"},{"issue":"2","key":"10.1111\/and.13126-BIB7000|and13126-cit-7000","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1038\/sj.pcan.4500712","article-title":"Role of zinc in the pathogenesis and treatment of prostate cancer: critical issues to resolve","volume":"7","author":"Costello","year":"2004","journal-title":"Prostate cancer and prostatic diseases"},{"issue":"1","key":"10.1111\/and.13126-BIB0033|and13126-cit-0033","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1095\/biolreprod59.1.7","article-title":"Role of cholesterol in sperm capacitation","volume":"59","author":"Cross","year":"1998","journal-title":"Biology of Reproduction"},{"issue":"7","key":"10.1111\/and.13126-BIB0034|and13126-cit-0034","doi-asserted-by":"crossref","first-page":"e1717","DOI":"10.1371\/journal.pntd.0001717","article-title":"Immune evasion and recognition of the syphilis spirochete in blood and skin of secondary syphilis patients: Two immunologically distinct compartments","volume":"6","author":"Cruz","year":"2012","journal-title":"PLoS Neglected Tropical Diseases"},{"issue":"6","key":"10.1111\/and.13126-BIB0035|and13126-cit-0035","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1016\/0090-4295(76)90518-5","article-title":"Asymptomatic bacteriospermia: Cause of infertility in men","volume":"8","author":"Dahlberg","year":"1976","journal-title":"Urology"},{"issue":"3","key":"10.1111\/and.13126-BIB0036|and13126-cit-0036","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.lfs.2007.05.005","article-title":"Alcohol-induced oxidative stress","volume":"81","author":"Das","year":"2007","journal-title":"Life Sciences"},{"issue":"12","key":"10.1111\/and.13126-BIB0037|and13126-cit-0037","doi-asserted-by":"crossref","first-page":"7560","DOI":"10.1073\/pnas.78.12.7560","article-title":"Timing of fertilization in mammals: Sperm cholesterol\/phospholipid ratio as a determinant of the capacitation interval","volume":"78","author":"Davis","year":"1981","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"1","key":"10.1111\/and.13126-BIB0038|and13126-cit-0038","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.bbapap.2007.08.024","article-title":"Sperm activation: Role of reactive oxygen species and kinases","volume":"1784","author":"Lamirande","year":"2008","journal-title":"Biochimica Et Biophysica Acta (BBA) - Proteins and Proteomics"},{"issue":"11","key":"10.1111\/and.13126-BIB0039|and13126-cit-0039","first-page":"75","article-title":"TLR4 in Chlamydia trachomatis infections: Knockout mice, STD patients and women with tubal factor subfertility","volume":"45","author":"Hartog","year":"2009","journal-title":"Drugs of Today"},{"issue":"2","key":"10.1111\/and.13126-BIB0040|and13126-cit-0040","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1046\/j.1439-0272.2003.00523.x","article-title":"Influence of autogenous leucocytes and Escherichia coli on sperm motility parameters in vitro","volume":"35","author":"Diemer","year":"2003","journal-title":"Andrologia"},{"issue":"5","key":"10.1111\/and.13126-BIB0041|and13126-cit-0041","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1111\/j.1365-2605.1996.tb00475.x","article-title":"Influence of Escherichia coli on motility parameters of human spermatozoa in vitro","volume":"19","author":"Diemer","year":"1996","journal-title":"International Journal of Andrology"},{"issue":"10","key":"10.1111\/and.13126-BIB0042|and13126-cit-0042","doi-asserted-by":"crossref","first-page":"e12783","DOI":"10.1111\/and.12783","article-title":"Oxidative stress and motility impairment in the semen of fertile males","volume":"49","author":"Dobrakowski","year":"2017","journal-title":"Andrologia."},{"issue":"5","key":"10.1111\/and.13126-BIB0043|and13126-cit-0043","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1016\/j.fertnstert.2012.01.124","article-title":"The incidence and effect of bacteriospermia and elevated seminal leukocytes on semen parameters","volume":"97","author":"Domes","year":"2012","journal-title":"Fertility and Sterility"},{"issue":"6","key":"10.1111\/and.13126-BIB0044|and13126-cit-0044","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1016\/S0015-0282(00)01591-0","article-title":"Effects of hydrogen peroxide on DNA and plasma membrane integrity of human spermatozoa","volume":"74","author":"Duru","year":"2000","journal-title":"Fertility and Sterility"},{"issue":"20","key":"10.1111\/and.13126-BIB0045|and13126-cit-0045","doi-asserted-by":"crossref","first-page":"E2100","DOI":"10.1073\/pnas.1401876111","article-title":"Antibiotics induce redox-related physiological alterations as part of their lethality","volume":"111","author":"Dwyer","year":"2014","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"5","key":"10.1111\/and.13126-BIB0046|and13126-cit-0046","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/j.mib.2009.06.018","article-title":"Role of reactive oxygen species in antibiotic action and resistance","volume":"12","author":"Dwyer","year":"2009","journal-title":"Current Opinion in Microbiology"},{"issue":"Suppl 1","key":"10.1111\/and.13126-BIB0047|and13126-cit-0047","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1093\/jac\/46.suppl_1.41","article-title":"Effect on the human normal microflora of oral antibiotics for treatment of urinary tract infections","volume":"46","author":"Edlund","year":"2000","journal-title":"Journal of Antimicrobial Chemotherapy"},{"issue":"9","key":"10.1111\/and.13126-BIB0048|and13126-cit-0048","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1007\/BF03347372","article-title":"Oxidative stress in the metabolic syndrome","volume":"29","author":"Esposito","year":"2006","journal-title":"Journal of Endocrinological Investigation"},{"issue":"8","key":"10.1111\/and.13126-BIB0049|and13126-cit-0049","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1093\/humrep\/dev141","article-title":"Impaired sperm motility in HIV-infected men: An unexpected adverse effect of efavirenz?","volume":"30","author":"Frapsauce","year":"2015","journal-title":"Human Reproduction"},{"issue":"6","key":"10.1111\/and.13126-BIB0050|and13126-cit-0050","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1023\/A:1012427224822","article-title":"Localization of glucose-6-phosphate dehydrogenase activity on ribosomes of granular endoplasmic reticulum, in peroxisomes and peripheral cytoplasm of rat liver parenchymal cells","volume":"33","author":"Frederiks","year":"2001","journal-title":"The Histochemical Journal"},{"issue":"3","key":"10.1111\/and.13126-BIB0051|and13126-cit-0051","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1097\/GCO.0b013e3282fcc00c","article-title":"Varicocele repair: Does it still have a role in infertility treatment?","volume":"20","author":"French","year":"2008","journal-title":"Current Opinion in Obstetrics and Gynecology"},{"issue":"6","key":"10.1111\/and.13126-BIB4002|and13126-cit-4002","doi-asserted-by":"crossref","first-page":"S389","DOI":"10.1016\/j.ajog.2008.10.024","article-title":"The clinical content of preconception care: preconception care for men","volume":"199","author":"Frey","year":"2008","journal-title":"American journal of obstetrics and gynecology"},{"issue":"6","key":"10.1111\/and.13126-BIB0052|and13126-cit-0052","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1007\/BF01644545","article-title":"The action of LPS porins and peptidoglycan fragments on human spermatozoa","volume":"16","author":"Galdiero","year":"1988","journal-title":"Infection"},{"issue":"2","key":"10.1111\/and.13126-BIB0053|and13126-cit-0053","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.fertnstert.2007.06.035","article-title":"Sperm DNA fragmentation in infertile men with genitourinary infection by Chlamydia trachomatis and Mycoplasma","volume":"90","author":"Gallegos","year":"2008","journal-title":"Fertility and Sterility"},{"issue":"1","key":"10.1111\/and.13126-BIB0054|and13126-cit-0054","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.jri.2013.03.004","article-title":"Sperm viral infection and male infertility: Focus on HBV, HCV, HIV, HPV, HSV, HCMV, and AAV","volume":"100","author":"Garolla","year":"2013","journal-title":"Journal of Reproductive Immunology"},{"issue":"2","key":"10.1111\/and.13126-BIB0055|and13126-cit-0055","doi-asserted-by":"crossref","first-page":"135","DOI":"10.3109\/01485019208987691","article-title":"NADH-dependent oxidoreductase (diaphorase) activity and isozyme pattern of sperm in infertile men","volume":"28","author":"Gavella","year":"1992","journal-title":"Archives of Andrology"},{"issue":"2","key":"10.1111\/and.13126-BIB0056|and13126-cit-0056","doi-asserted-by":"crossref","first-page":"198","DOI":"10.2164\/jandrol.107.003566","article-title":"Assessment of Chlamydia trachomatis, Ureaplasma urealyticum, Ureaplasma parvum, Mycoplasma hominis, and Mycoplasma genitalium in semen and first void urine specimens of asymptomatic male partners of infertile couples","volume":"29","author":"Gdoura","year":"2008","journal-title":"Journal of Andrology"},{"issue":"12","key":"10.1111\/and.13126-BIB0057|and13126-cit-0057","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1038\/nrurol.2014.285","article-title":"Male infertility: A public health issue caused by sexually transmitted pathogens","volume":"11","author":"Gimenes","year":"2014","journal-title":"Nature Reviews Urology"},{"issue":"3","key":"10.1111\/and.13126-BIB0058|and13126-cit-0058","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1002\/j.1939-4640.1996.tb01783.x","article-title":"Development of an image analysis system to monitor the retention of residual cytoplasm by human spermatozoa: Correlation with biochemical markers of the cytoplasmic space, oxidative stress, and sperm function","volume":"17","author":"Gomez","year":"1996","journal-title":"Journal of Andrology"},{"issue":"6","key":"10.1111\/and.13126-BIB0059|and13126-cit-0059","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1111\/j.1365-2605.1994.tb01260.x","article-title":"An in vitro promoting role for hydrogen peroxide in human sperm capacitation","volume":"17","author":"Griveau","year":"1994","journal-title":"International Journal of Andrology"},{"issue":"3","key":"10.1111\/and.13126-BIB0060|and13126-cit-0060","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1038\/aja.2010.94","article-title":"Expression of E-cadherin and \u03b1-catenin in a varicocele-induced infertility rat model","volume":"13","author":"Ha","year":"2011","journal-title":"Asian Journal of Andrology"},{"issue":"5","key":"10.1111\/and.13126-BIB0061|and13126-cit-0061","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1111\/andr.12074","article-title":"Differential expression of novel biomarkers (TLR-2, TLR-4, COX-2, and Nrf-2) of inflammation and oxidative stress in semen of leukocytospermia patients","volume":"3","author":"Hagan","year":"2015","journal-title":"Andrology"},{"issue":"3","key":"10.1111\/and.13126-BIB0062|and13126-cit-0062","first-page":"241","article-title":"Impact of oxidative stress on male infertility","volume":"77","author":"Hampl","year":"2012","journal-title":"Ceska Gynekologie"},{"issue":"3","key":"10.1111\/and.13126-BIB0063|and13126-cit-0063","doi-asserted-by":"crossref","first-page":"143","DOI":"10.5534\/wjmh.2015.33.3.143","article-title":"Smoking and male infertility: An evidence-based review","volume":"33","author":"Harlev","year":"2015","journal-title":"The World Journal of Men's Health"},{"issue":"2","key":"10.1111\/and.13126-BIB0064|and13126-cit-0064","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/0006-291X(92)91123-8","article-title":"Selective inhibition of protein tyrosine phosphatase activities by H2O2 and vanadate in vitro","volume":"188","author":"Hecht","year":"1992","journal-title":"Biochemical and Biophysical Research Communications"},{"key":"10.1111\/and.13126-BIB0066|and13126-cit-0066","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/978-1-4614-3335-4_25","volume-title":"Male infertility","author":"Henkel","year":"2012"},{"issue":"3","key":"10.1111\/and.13126-BIB0067|and13126-cit-0067","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1111\/j.1745-7262.2007.00270.x","article-title":"Age-related changes in seminal polymorphonuclear elastase in men with asymptomatic inflammation of the genital tract","volume":"9","author":"Henkel","year":"2007","journal-title":"Asian Journal of Andrology"},{"issue":"8","key":"10.1111\/and.13126-BIB4012|and13126-cit-4012","doi-asserted-by":"crossref","first-page":"2557","DOI":"10.1016\/j.fertnstert.2011.05.014","article-title":"Semen and hormonal parameters in men with chronic hepatitis C infection","volume":"95","author":"Hofny","year":"2011","journal-title":"Fertility and sterility"},{"issue":"1","key":"10.1111\/and.13126-BIB0068|and13126-cit-0068","doi-asserted-by":"crossref","first-page":"71.e1","DOI":"10.1016\/j.ajog.2009.07.042","article-title":"Chlamydia trachomatis, Mycoplasma genitalium, Neisseria gonorrhoeae, human papillomavirus, and polyomavirus are not detectable in human tissue with epithelial ovarian cancer, borderline tumor, or benign conditions","volume":"202","author":"Idahl","year":"2010","journal-title":"American Journal of Obstetrics & Gynecology"},{"issue":"3","key":"10.1111\/and.13126-BIB0069|and13126-cit-0069","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1016\/S0025-7125(16)33449-6","article-title":"The late manifestations of syphilis: Skeletal, visceral and cardiovascular","volume":"48","author":"Kampmeier","year":"1964","journal-title":"Medical Clinics of North America"},{"issue":"3","key":"10.1111\/and.13126-BIB0070|and13126-cit-0070","doi-asserted-by":"crossref","first-page":"e33471","DOI":"10.1371\/journal.pone.0033471","article-title":"Effects of hepatitis B virus S protein exposure on sperm membrane integrity and functions","volume":"7","author":"Kang","year":"2012","journal-title":"PLoS One"},{"issue":"11","key":"10.1111\/and.13126-BIB0071|and13126-cit-0071","first-page":"67","article-title":"TLR2 haplotypes in the susceptibility to and severity of Chlamydia trachomatis infections in Dutch women","volume":"45","author":"Karimi","year":"2009","journal-title":"Drugs of Today"},{"key":"10.1111\/and.13126-BIB0072|and13126-cit-0072","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1007\/978-1-61779-776-7_26","volume-title":"Studies on men's health and fertility","author":"Kashou","year":"2012"},{"issue":"1","key":"10.1111\/and.13126-BIB0073|and13126-cit-0073","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1007\/s00404-011-1898-6","article-title":"HIV-infection and modern antiretroviral therapy impair sperm quality","volume":"284","author":"Kehl","year":"2011","journal-title":"Archives of Gynecology and Obstetrics"},{"issue":"2","key":"10.1111\/and.13126-BIB0074|and13126-cit-0074","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/S0015-0282(02)04582-X","article-title":"Effects of maternal and paternal alcohol consumption on the success rates of in vitro fertilization and gamete intrafallopian transfer","volume":"79","author":"Klonoff-Cohen","year":"2003","journal-title":"Fertility and Sterility"},{"issue":"4","key":"10.1111\/and.13126-BIB0075|and13126-cit-0075","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/s00240-002-0269-y","article-title":"Relationship between seminal plasma interleukin-6 and tumor necrosis factor \u03b1 levels with semen parameters in fertile and infertile men","volume":"30","author":"Ko\u00e7ak","year":"2002","journal-title":"Urological Research"},{"issue":"5","key":"10.1111\/and.13126-BIB0076|and13126-cit-0076","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.arcmed.2005.12.002","article-title":"Plasma leptin and its relationship with lipid peroxidation and nitric oxide in obese female patients with or without hypertension","volume":"37","author":"Konukoglu","year":"2006","journal-title":"Archives of Medical Research"},{"issue":"1","key":"10.1111\/and.13126-BIB0077|and13126-cit-0077","doi-asserted-by":"crossref","first-page":"3","DOI":"10.4103\/0253-7184.156680","article-title":"Antibiotic resistance in prevalent bacterial and protozoan sexually transmitted infections","volume":"36","author":"Krupp","year":"2015","journal-title":"Indian Journal of Sexually Transmitted Diseases"},{"issue":"1","key":"10.1111\/and.13126-BIB0078|and13126-cit-0078","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.ijheh.2014.08.006","article-title":"Effect of cigarette smoke on DNA damage, oxidative stress, and morphological alterations in mouse testis and spermatozoa","volume":"218","author":"La Maestra","year":"2015","journal-title":"International Journal of Hygiene and Environmental Health"},{"issue":"1","key":"10.1111\/and.13126-BIB0079|and13126-cit-0079","doi-asserted-by":"crossref","first-page":"e19","DOI":"10.1016\/j.ejim.2011.08.011","article-title":"Sperm DNA damage in patients with chronic viral C hepatitis","volume":"23","author":"Vignera","year":"2012","journal-title":"European Journal of Internal Medicine"},{"issue":"1","key":"10.1111\/and.13126-BIB0080|and13126-cit-0080","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1111\/j.1365-2605.1993.tb01148.x","article-title":"A positive role for the superoxide anion in triggering hyperactivation and capacitation of human spermatozoa","volume":"16","author":"Lamirande","year":"1993","journal-title":"International Journal of Andrology"},{"issue":"3","key":"10.1111\/and.13126-BIB0082|and13126-cit-0082","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.reprotox.2012.06.007","article-title":"Investigating ROS sources in male infertility: A common end for numerous pathways","volume":"34","author":"Lavranos","year":"2012","journal-title":"Reproductive Toxicology"},{"issue":"2","key":"10.1111\/and.13126-BIB0083|and13126-cit-0083","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/aji.12529","article-title":"Metabolic syndrome is associated with increased seminal inflammatory cytokines and reproductive dysfunction in a case-controlled male cohort","volume":"76","author":"Leisegang","year":"2016","journal-title":"American Journal of Reproductive Immunology"},{"key":"10.1111\/and.13126-BIB0084|and13126-cit-0084","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1186\/s12958-018-0341-2","article-title":"The in vitro modulation of steroidogenesis by inflammatory cytokines and insulin in TM3 Leydig cells","volume":"16","author":"Leisegang","year":"2018","journal-title":"Reproductive Biology and Endocrinology"},{"issue":"47","key":"10.1111\/and.13126-BIB0085|and13126-cit-0085","doi-asserted-by":"crossref","first-page":"33419","DOI":"10.1074\/jbc.274.47.33419","article-title":"Toll-like receptor 2 functions as a pattern recognition receptor for diverse bacterial products","volume":"274","author":"Lien","year":"1999","journal-title":"Journal of Biological Chemistry"},{"issue":"12","key":"10.1111\/and.13126-BIB0086|and13126-cit-0086","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1086\/652861","article-title":"Treatment of bacterial prostatitis","volume":"50","author":"Lipsky","year":"2010","journal-title":"Clinical Infectious Diseases"},{"issue":"2","key":"10.1111\/and.13126-BIB0087|and13126-cit-0087","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1111\/j.1439-0272.2009.00970.x","article-title":"Impact of chronic viral diseases on semen parameters","volume":"42","author":"Lorusso","year":"2010","journal-title":"Andrologia"},{"issue":"14","key":"10.1111\/and.13126-BIB0088|and13126-cit-0088","doi-asserted-by":"crossref","first-page":"7199","DOI":"10.1128\/JVI.00321-06","article-title":"Hepatitis C virus triggers mitochondrial permeability transition with production of reactive oxygen species, leading to DNA damage and STAT3 activation","volume":"80","author":"Machida","year":"2006","journal-title":"Journal of Virology"},{"issue":"3","key":"10.1111\/and.13126-BIB0089|and13126-cit-0089","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1152\/ajplegacy.1943.138.3.512","article-title":"The role of oxygen in the metabolism and motility of human spermatozoa","volume":"138","author":"MacLeod","year":"1943","journal-title":"American Journal of Physiology-Legacy Content"},{"issue":"5","key":"10.1111\/and.13126-BIB0090|and13126-cit-0090","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1016\/j.ijantimicag.2006.09.027","article-title":"Efficacy of repeated cycles of combination therapy for the eradication of infecting organisms in chronic bacterial prostatitis","volume":"29","author":"Magri","year":"2007","journal-title":"International Journal of Antimicrobial Agents"},{"issue":"3","key":"10.1111\/and.13126-BIB4003|and13126-cit-4003","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1111\/j.1600-0897.2009.00786.x","article-title":"Expression of IL-6, IL-8, TNF-\u03b1, IL-10, HSP-60, Anti-HSP-60 Antibodies, and Anti-sperm Antibodies, in Semen of Men with Leukocytes and\/or Bacteria","volume":"63","author":"Mart\u00ednez-Prado","year":"2010","journal-title":"American Journal of Reproductive Immunology"},{"issue":"1","key":"10.1111\/and.13126-BIB4020|and13126-cit-4020","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1111\/j.1745-7262.2007.00238.x","article-title":"Sperm lipid peroxidation and pro-inflammatory cytokines","volume":"9","author":"Mart\u00ednez","year":"2007","journal-title":"Asian Journal of Andrology"},{"issue":"4","key":"10.1111\/and.13126-BIB0092|and13126-cit-0092","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1177\/1753425913493453","article-title":"Activation of NOD receptors by Neisseria gonorrhoeae modulates the innate immune response","volume":"20","author":"Mavrogiorgos","year":"2014","journal-title":"Innate Immunity"},{"issue":"3","key":"10.1111\/and.13126-BIB4004|and13126-cit-4004","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1016\/j.fertnstert.2016.01.013","article-title":"Aging and the environment affect gamete and embryo potential: can we intervene?","volume":"105","author":"Meldrum","year":"2016","journal-title":"Fertility and sterility"},{"issue":"1","key":"10.1111\/and.13126-BIB0093|and13126-cit-0093","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1007\/s10815-008-9283-5","article-title":"The presence of bacteria species in semen and sperm quality","volume":"26","author":"Moretti","year":"2009","journal-title":"Journal of Assisted Reproduction and Genetics"},{"issue":"4","key":"10.1111\/and.13126-BIB0094|and13126-cit-0094","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/j.bpobgyn.2014.10.006","article-title":"Metabolic syndrome and infertility in men","volume":"29","author":"Morrison","year":"2015","journal-title":"Best Practice & Research Clinical Obstetrics & Gynaecology"},{"issue":"12","key":"10.1111\/and.13126-BIB0095|and13126-cit-0095","first-page":"958","article-title":"Exploring the full spectrum of macrophage activation","volume":"8","author":"Mosser","year":"2008","journal-title":"NatureReviews Immunology"},{"issue":"4","key":"10.1111\/and.13126-BIB0096|and13126-cit-0096","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1016\/j.fertnstert.2005.04.025","article-title":"Effect of chronic alcoholism on male fertility hormones and semen quality","volume":"84","author":"Muthusami","year":"2005","journal-title":"Fertility and Sterility"},{"issue":"4","key":"10.1111\/and.13126-BIB0097|and13126-cit-0097","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1111\/j.1439-0272.2005.00668.x","article-title":"Relationship of interleukin-6 with semen characteristics and oxidative stress in vasectomy reversal patients","volume":"37","author":"Nandipati","year":"2005","journal-title":"Andrologia"},{"issue":"3","key":"10.1111\/and.13126-BIB0098|and13126-cit-0098","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1002\/j.1939-4640.1994.tb00436.x","article-title":"Increased levels of interleukin-6 in seminal plasma of infertile men","volume":"15","author":"Naz","year":"1994","journal-title":"Journal of Andrology"},{"issue":"3","key":"10.1111\/and.13126-BIB0099|and13126-cit-0099","doi-asserted-by":"crossref","first-page":"S116","DOI":"10.1067\/mjd.2001.117432","article-title":"Estrogen production and action","volume":"45","author":"Nelson","year":"2001","journal-title":"Journal of the American Academy of Dermatology"},{"issue":"12","key":"10.1111\/and.13126-BIB0100|and13126-cit-0100","doi-asserted-by":"crossref","first-page":"e0143304","DOI":"10.1371\/journal.pone.0143304","article-title":"Global estimates of the prevalence and incidence of four curable sexually transmitted infections in 2012 based on systematic review and global reporting","volume":"10","author":"Newman","year":"2015","journal-title":"PloS One"},{"issue":"3","key":"10.1111\/and.13126-BIB0101|and13126-cit-0101","doi-asserted-by":"crossref","first-page":"a006049","DOI":"10.1101\/cshperspect.a006049","article-title":"Signaling in innate immunity and inflammation","volume":"4","author":"Newton","year":"2012","journal-title":"Cold Spring Harbor Perspectives in Biology"},{"issue":"11","key":"10.1111\/and.13126-BIB0102|and13126-cit-0102","doi-asserted-by":"crossref","first-page":"759","DOI":"10.3109\/09513590.2014.938623","article-title":"Alcohol consumption and in vitro fertilization: A review of the literature","volume":"30","author":"Nicolau","year":"2014","journal-title":"Gynecological Endocrinology"},{"issue":"10","key":"10.1111\/and.13126-BIB0103|and13126-cit-0103","doi-asserted-by":"crossref","first-page":"2756","DOI":"10.1093\/humrep\/13.10.2756","article-title":"Ureaplasma urealyticum reduces motility and induces membrane alterations in human spermatozoa","volume":"13","author":"Nunez-Calonge","year":"1998","journal-title":"Human Reproduction (Oxford, England)"},{"issue":"3","key":"10.1111\/and.13126-BIB0104|and13126-cit-0104","first-page":"455","article-title":"Quinolones: A comprehensive review","volume":"65","author":"Oliphant","year":"2002","journal-title":"American Family Physician"},{"issue":"2","key":"10.1111\/and.13126-BIB0105|and13126-cit-0105","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1159\/000020135","article-title":"Increased nitric oxide production in the spermatic vein of patients with varicocele","volume":"37","author":"Ozbek","year":"2000","journal-title":"European Urology"},{"issue":"2","key":"10.1111\/and.13126-BIB4005|and13126-cit-4005","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/s00404-003-0572-z","article-title":"Semen quality of smoking and non-smoking men in infertile couples in a Turkish population","volume":"271","author":"Ozgur","year":"2005","journal-title":"Archives of gynecology and obstetrics"},{"issue":"4","key":"10.1111\/and.13126-BIB0106|and13126-cit-0106","doi-asserted-by":"crossref","first-page":"253","DOI":"10.4161\/spmg.21362","article-title":"Impact of obesity on male fertility, sperm function and molecular composition","volume":"2","author":"Palmer","year":"2012","journal-title":"Spermatogenesis"},{"issue":"3","key":"10.1111\/and.13126-BIB0107|and13126-cit-0107","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1016\/j.fertnstert.2007.03.057","article-title":"Semen quality and oxidative stress scores in fertile and infertile patients with varicocele","volume":"89","author":"Pasqualotto","year":"2008","journal-title":"Fertility and Sterility"},{"issue":"14","key":"10.1111\/and.13126-BIB0108|and13126-cit-0108","doi-asserted-by":"crossref","first-page":"8466","DOI":"10.1073\/pnas.1032913100","article-title":"Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of PGC1 and NRF1","volume":"100","author":"Patti","year":"2003","journal-title":"Proceedings of the National Academy of Sciences of the United States of America"},{"issue":"6","key":"10.1111\/and.13126-BIB0109|and13126-cit-0109","doi-asserted-by":"crossref","first-page":"2151","DOI":"10.1016\/j.fertnstert.2009.12.080","article-title":"Decrease of mitochondrial DNA level in sperm from patients infected with human immunodeficiency virus-1 linked to nucleoside analogue reverse transcriptase inhibitors","volume":"94","author":"Pavili","year":"2010","journal-title":"Fertility and Sterility"},{"issue":"2","key":"10.1111\/and.13126-BIB0110|and13126-cit-0110","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/S0015-0282(16)56895-2","article-title":"Reactive oxygen species released by activated neutrophils, but not by deficient spermatozoa, are sufficient to affect normal sperm motility","volume":"62","author":"Plante","year":"1994","journal-title":"Fertility and Sterility"},{"issue":"3","key":"10.1111\/and.13126-BIB0111|and13126-cit-0111","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1111\/aji.12537","article-title":"Effect of hepatitis B virus infection on sperm quality and oxidative stress state of the semen of infertile males","volume":"76","author":"Qian","year":"2016","journal-title":"American Journal of Reproductive Immunology"},{"issue":"1","key":"10.1111\/and.13126-BIB0112|and13126-cit-0112","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/S0015-0282(16)57674-2","article-title":"Oxidative stress and interleukins in seminal plasma during leukocytospermia","volume":"64","author":"Rajasekaran","year":"1995","journal-title":"Fertility and Sterility"},{"issue":"3","key":"10.1111\/and.13126-BIB0113|and13126-cit-0113","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1111\/j.1439-0272.1992.tb02627.x","article-title":"Sperm plasma membrane integrity in fertile and infertile men","volume":"24","author":"Ramirez","year":"1992","journal-title":"Andrologia"},{"issue":"4","key":"10.1111\/and.13126-BIB0114|and13126-cit-0114","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1095\/biolreprod63.4.1041","article-title":"In vivo and in vitro impairment of human and ram sperm nuclear chromatin integrity by sexually transmitted Ureaplasma urealyticum infection","volume":"63","author":"Reichart","year":"2000","journal-title":"Biology of Reproduction"},{"issue":"1","key":"10.1111\/and.13126-BIB0115|and13126-cit-0115","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/j.1365-2605.2007.00752.x","article-title":"Association between tobacco exposure and reproductive parameters in adolescent males","volume":"31","author":"Richthoff","year":"2008","journal-title":"International Journal of Andrology"},{"issue":"2","key":"10.1111\/and.13126-BIB0116|and13126-cit-0116","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1097\/00007435-200202000-00001","article-title":"Incidence and repeat infection rates of Chlamydia trachomatis among male and female patients in an STD clinic: Implications for screening and rescreening","volume":"29","author":"Rietmeijer","year":"2002","journal-title":"Sexually Transmitted Diseases"},{"issue":"1","key":"10.1111\/and.13126-BIB0117|and13126-cit-0117","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1093\/humrep\/deg004","article-title":"Preliminary report on nitric oxide-mediated oxidative damage in adolescent varicocele","volume":"18","author":"Romeo","year":"2003","journal-title":"Human Reproduction"},{"issue":"4","key":"10.1111\/and.13126-BIB4008|and13126-cit-4008","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/S0015-0282(98)00261-1","article-title":"Smoking cigarettes is associated with increased sperm disomy in teenage men18","volume":"70","author":"Rubes","year":"1998","journal-title":"Fertility and sterility"},{"issue":"9","key":"10.1111\/and.13126-BIB0118|and13126-cit-0118","doi-asserted-by":"crossref","first-page":"413","DOI":"10.3923\/pjbs.2010.413.422","article-title":"The incriminating role of reactive oxygen species in idiopathic male infertility: An evidence based evaluation","volume":"13","author":"Saalu","year":"2010","journal-title":"Pakistan Journal of Biological Sciences"},{"issue":"4","key":"10.1111\/and.13126-BIB0119|and13126-cit-0119","doi-asserted-by":"crossref","first-page":"231","DOI":"10.29252\/ijrm.14.4.231","article-title":"Etiologies of sperm oxidative stress","volume":"14","author":"Sabeti","year":"2016","journal-title":"International Journal of Reproductive BioMedicine"},{"issue":"104","key":"10.1111\/and.13126-BIB4011|and13126-cit-4011","doi-asserted-by":"crossref","first-page":"20141197","DOI":"10.1098\/rsif.2014.1197","article-title":"Many hepatitis C reinfections that spontaneously clear may be undetected: Markov-chain Monte Carlo analysis of observational study data","volume":"12","author":"Sacks-Davis","year":"2015","journal-title":"Journal of The Royal Society Interface"},{"issue":"3","key":"10.1111\/and.13126-BIB0120|and13126-cit-0120","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/j.fertnstert.2005.03.052","article-title":"Relationship between semen quality and tobacco chewing in men undergoing infertility evaluation","volume":"84","author":"Said","year":"2005","journal-title":"Fertility and Sterility"},{"issue":"6","key":"10.1111\/and.13126-BIB0121|and13126-cit-0121","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1016\/S0015-0282(02)04237-1","article-title":"Leukocytospermia is associated with increased reactive oxygen species production by human spermatozoa","volume":"78","author":"Saleh","year":"2002","journal-title":"Fertility and Sterility"},{"issue":"3","key":"10.1111\/and.13126-BIB0123|and13126-cit-0123","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/j.mefs.2013.02.004","article-title":"Leukocytospermia: Overview of diagnosis, implications, and management of a controversial finding","volume":"18","author":"Sandoval","year":"2013","journal-title":"Middle East Fertility Society Journal"},{"issue":"3","key":"10.1111\/and.13126-BIB0124|and13126-cit-0124","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1002\/j.1939-4640.2003.tb02693.x","article-title":"Male genital tract inflammation: The role of selected interleukins in regulation of pro-oxidant and antioxidant enzymatic substances in seminal plasma","volume":"24","author":"Sanocka","year":"2003","journal-title":"Journal of Andrology"},{"issue":"4","key":"10.1111\/and.13126-BIB0125|and13126-cit-0125","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1002\/j.1939-4640.1996.tb01813.x","article-title":"Oxidative stress and male infertility","volume":"17","author":"Sanocka","year":"1996","journal-title":"Journal of Andrology"},{"issue":"1-2","key":"10.1111\/and.13126-BIB0126|and13126-cit-0126","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.jri.2005.06.003","article-title":"Bacterial infection and semen quality","volume":"67","author":"Sanocka-Maciejewska","year":"2005","journal-title":"Journal of Reproductive Immunology"},{"key":"10.1111\/and.13126-BIB4006|and13126-cit-4006","unstructured":"Schmid , G. Rowley , J. T. Samuelson , J. Tun , Y. Guraiib , M. 2009 World Health Organization (WHO) 2005 Global Estimates of the Incidence and Prevalence of Sexually Transmitted Infections (STIs)"},{"issue":"2","key":"10.1111\/and.13126-BIB0127|and13126-cit-0127","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1111\/j.1439-0272.2008.00837.x","article-title":"Chronic orchitis: A neglected cause of male infertility?","volume":"40","author":"Schuppe","year":"2008","journal-title":"Andrologia"},{"issue":"11","key":"10.1111\/and.13126-BIB0128|and13126-cit-0128","doi-asserted-by":"crossref","first-page":"5455","DOI":"10.4049\/jimmunol.160.11.5455","article-title":"Treponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides activate monocytic cells via a CD14-dependent pathway distinct from that used by lipopolysaccharide","volume":"160","author":"Sellati","year":"1998","journal-title":"The Journal of Immunology"},{"issue":"9","key":"10.1111\/and.13126-BIB0129|and13126-cit-0129","doi-asserted-by":"crossref","first-page":"2608","DOI":"10.1093\/humrep\/dei063","article-title":"Increased expression of Leydig cell haem oxygenase-1 preserves spermatogenesis in varicocele","volume":"20","author":"Shiraishi","year":"2005","journal-title":"Human Reproduction"},{"issue":"22","key":"10.1111\/and.13126-BIB0130|and13126-cit-0130","first-page":"7293","article-title":"Metabolism of diaziquone by NAD (P) H:(quinone acceptor) oxidoreductase (DT-diaphorase): Role in diaziquone-induced DNA damage and cytotoxicity in human colon carcinoma cells","volume":"50","author":"Siegel","year":"1990","journal-title":"CancerResearch"},{"issue":"3","key":"10.1111\/and.13126-BIB0131|and13126-cit-0131","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1007\/s00441-012-1370-3","article-title":"Kinases, phosphatases and proteases during sperm capacitation","volume":"349","author":"Signorelli","year":"2012","journal-title":"Cell and Tissue Research"},{"issue":"2","key":"10.1111\/and.13126-BIB0132|and13126-cit-0132","doi-asserted-by":"crossref","first-page":"ftv126","DOI":"10.1093\/femspd\/ftv126","article-title":"Effect of cytokine level variations in individuals on the progression and outcome of bacterial urogenital infections-A meta-analysis","volume":"74","author":"Singer","year":"2016","journal-title":"Pathogens and Disease"},{"issue":"3","key":"10.1111\/and.13126-BIB4007|and13126-cit-4007","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1097\/GCO.0b013e3282fc9c1e","article-title":"Cigarette smoking and reproductive function","volume":"20","author":"Soares","year":"2008","journal-title":"Current Opinion in Obstetrics and Gynecology"},{"issue":"12","key":"10.1111\/and.13126-BIB0134|and13126-cit-0134","doi-asserted-by":"crossref","first-page":"4413","DOI":"10.1210\/endo.141.12.7824","article-title":"Molecular cloning and expression of a functionally different alternative splice variant of prointerleukin-1\u03b1 from the rat testis","volume":"141","author":"Sultana","year":"2000","journal-title":"Endocrinology"},{"issue":"2","key":"10.1111\/and.13126-BIB0135|and13126-cit-0135","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.tips.2010.11.006","article-title":"Reactive oxygen species and insulin resistance: The good, the bad and the ugly","volume":"32","author":"Tiganis","year":"2011","journal-title":"Trends in Pharmacological Sciences"},{"issue":"1","key":"10.1111\/and.13126-BIB0136|and13126-cit-0136","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1152\/physrev.00017.2012","article-title":"Hypoxia and adipose tissue function and dysfunction in obesity","volume":"93","author":"Trayhurn","year":"2013","journal-title":"Physiological Reviews"},{"issue":"3","key":"10.1111\/and.13126-BIB0137|and13126-cit-0137","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1093\/humupd\/dmn004","article-title":"Oxidative stress and male infertility-a clinical perspective","volume":"14","author":"Tremellen","year":"2008","journal-title":"Human Reproduction Update"},{"issue":"3","key":"10.1111\/and.13126-BIB0138|and13126-cit-0138","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1128\/IAI.64.3.1048-1050.1996","article-title":"Lesions of primary and secondary syphilis contain activated cytolytic T cells","volume":"64","author":"Voorhis","year":"1996","journal-title":"Infection and Immunity"},{"issue":"6","key":"10.1111\/and.13126-BIB0139|and13126-cit-0139","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1111\/1574-6976.12026","article-title":"Antimicrobial strategies centered around reactive oxygen species-bactericidal antibiotics, photodynamic therapy, and beyond","volume":"37","author":"Vatansever","year":"2013","journal-title":"FEMS Microbiology Reviews"},{"issue":"11-12","key":"10.1111\/and.13126-BIB0140|and13126-cit-0140","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1002\/bies.20838","article-title":"Avoiding bad genes: Oxidatively damaged DNA in germ line and mate choice","volume":"30","author":"Velando","year":"2008","journal-title":"Bioessays"},{"issue":"1","key":"10.1111\/and.13126-BIB0141|and13126-cit-0141","first-page":"65","article-title":"Sperm output in patients with primary infertility and hepatitis B or C virus; negative influence of HBV infection during concomitant varicocele","volume":"97","author":"Vicari","year":"2006","journal-title":"Minerva Medica"},{"issue":"4","key":"10.1111\/and.13126-BIB0142|and13126-cit-0142","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1046\/j.1439-0272.2003.00564.x","article-title":"Reactive oxygen species induce reversible capacitation in human spermatozoa","volume":"35","author":"Villegas","year":"2003","journal-title":"Andrologia"},{"issue":"7029","key":"10.1111\/and.13126-BIB4009|and13126-cit-4009","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1136\/bmj.312.7029.506","article-title":"Worldwide decline in semen quality might be due to smoking","volume":"312","author":"Vine","year":"1996","journal-title":"BMJ: British Medical Journal"},{"issue":"4","key":"10.1111\/and.13126-BIB0143|and13126-cit-0143","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1242\/dev.121.4.1129","article-title":"Capacitation of mouse spermatozoa. I. Correlation between the capacitation state and protein tyrosine phosphorylation","volume":"121","author":"Visconti","year":"1995","journal-title":"Development"},{"issue":"9","key":"10.1111\/and.13126-BIB0144|and13126-cit-0144","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.1002\/jmv.23991","article-title":"Factors affecting sperm fertilizing capacity in men infected with HIV","volume":"86","author":"Wang","year":"2014","journal-title":"Journal of Medical Virology"},{"issue":"4","key":"10.1111\/and.13126-BIB0145|and13126-cit-0145","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/S0302-2838(02)00367-6","article-title":"EAU guidelines on male infertility","volume":"42","author":"Weidner","year":"2002","journal-title":"European Urology"},{"issue":"4","key":"10.1111\/and.13126-BIB0146|and13126-cit-0146","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1136\/sti.2005.018598","article-title":"Mycoplasma genitalium: A common cause of persistent urethritis among men treated with doxycycline","volume":"82","author":"Wikstr\u00f6m","year":"2006","journal-title":"Sexually Transmitted Infections"},{"issue":"3","key":"10.1111\/and.13126-BIB0147|and13126-cit-0147","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1016\/j.fertnstert.2011.01.002","article-title":"The great debate: Varicocele treatment and impact on fertility","volume":"95","author":"Will","year":"2011","journal-title":"Fertility and Sterility"},{"issue":"6","key":"10.1111\/and.13126-BIB4010|and13126-cit-4010","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1016\/S0015-0282(16)57588-8","article-title":"The biologic significance of white blood cells in semen","volume":"63","author":"Wolff","year":"1995","journal-title":"Fertil Steril"},{"issue":"1","key":"10.1111\/and.13126-BIB0148|and13126-cit-0148","doi-asserted-by":"crossref","first-page":"348","DOI":"10.4049\/jimmunol.168.1.348","article-title":"Toll-like receptor 2 is required for innate, but not acquired, host defense to Borrelia burgdorferi","volume":"168","author":"Wooten","year":"2002","journal-title":"The Journal of Immunology"},{"issue":"5","key":"10.1111\/and.13126-BIB0149|and13126-cit-0149","doi-asserted-by":"crossref","first-page":"1520","DOI":"10.1161\/01.CIR.91.5.1520","article-title":"Hypoxic stress induces cardiac myocyte-derived interleukin-6","volume":"91","author":"Yamauchi-Takihara","year":"1995","journal-title":"Circulation"},{"key":"10.1111\/and.13126-BIB0150|and13126-cit-0150","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.mib.2017.09.002","article-title":"Antibiotic efficacy-Context matters","volume":"39","author":"Yang","year":"2017","journal-title":"Current Opinion in Microbiology"},{"issue":"6","key":"10.1111\/and.13126-BIB0151|and13126-cit-0151","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1258\/ijsa.2008.008334","article-title":"Prevalence of Ureaplasma urealyticum and Ureaplasma parvum in semen of infertile and healthy men","volume":"20","author":"Zeighami","year":"2009","journal-title":"International Journal of STD & AIDS"},{"issue":"6","key":"10.1111\/and.13126-BIB0152|and13126-cit-0152","doi-asserted-by":"crossref","first-page":"e12685","DOI":"10.1111\/and.12685","article-title":"Inflammatory and anti-inflammatory cytokines in the seminal plasma of infertile men suffering from varicocele","volume":"49","author":"Zeinali","year":"2017","journal-title":"Andrologia"},{"issue":"7","key":"10.1111\/and.13126-BIB0153|and13126-cit-0153","first-page":"589","article-title":"Decline of semen quality and increase of leukocytes with cigarette smoking in infertile men","volume":"11","author":"Zhang","year":"2013","journal-title":"Iranian Journal of Reproductive Medicine"},{"key":"10.1111\/and.13126-BIB0154|and13126-cit-0154","article-title":"Ureaplasma spp. in male infertility and its relationship with semen quality and seminal plasma components","author":"Zhou","year":"2017","journal-title":"Journal of Microbiology, Immunology and Infection"},{"issue":"2","key":"10.1111\/and.13126-BIB0155|and13126-cit-0155","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S1001-7844(08)60008-5","article-title":"Ureaplasma urealyticum or Mycoplasma hominis infections and semen quality of infertile men in Abidjan","volume":"19","author":"Zinzendorf","year":"2008","journal-title":"Journal of Reproduction and Contraception"}],"container-title":["Andrologia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fand.13126","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/onlinelibrary.wiley.com\/wol1\/doi\/10.1111\/and.13126\/fullpdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,13]],"date-time":"2024-07-13T10:07:49Z","timestamp":1720865269000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/and.13126"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12]]},"references-count":165,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2018,12]]}},"URL":"https:\/\/doi.org\/10.1111\/and.13126","archive":["Portico"],"relation":{},"ISSN":["0303-4569"],"issn-type":[{"value":"0303-4569","type":"print"}],"subject":[],"published":{"date-parts":[[2018,12]]}}}