{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T09:50:51Z","timestamp":1784713851338,"version":"3.55.0"},"reference-count":65,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2019,3,15]],"date-time":"2019-03-15T00:00:00Z","timestamp":1552608000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2019,3,15]],"date-time":"2019-03-15T00:00:00Z","timestamp":1552608000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Andrologia"],"published-print":{"date-parts":[[2019,7]]},"DOI":"10.1111\/and.13268","type":"journal-article","created":{"date-parts":[[2019,3,15]],"date-time":"2019-03-15T07:25:51Z","timestamp":1552634751000},"page":"e13268","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":14,"title":["Effects of long\u2010term paroxetine or bupropion treatment on puberty onset, reproductive and feeding parameters in adolescent male rats"],"prefix":"10.1155","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5740-9518","authenticated-orcid":false,"given":"Ahmet","family":"Yardimci","sequence":"first","affiliation":[{"name":"Department of Physiology, Faculty of Medicine Firat University Elazig Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nazife","family":"Ulker","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Medicine Firat University Elazig Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ozgur","family":"Bulmus","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Medicine Firat University Elazig Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nalan","family":"Kaya","sequence":"additional","affiliation":[{"name":"Department of Histology and Embryology, Faculty of Medicine Firat University Elazig Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neriman","family":"Colakoglu","sequence":"additional","affiliation":[{"name":"Department of Histology and Embryology, Faculty of Medicine Firat University Elazig Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mete","family":"Ozcan","sequence":"additional","affiliation":[{"name":"Department of Biophysics, Faculty of Medicine Firat University Elazig Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sinan","family":"Canpolat","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Medicine Firat University Elazig Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haluk","family":"Kelestimur","sequence":"additional","affiliation":[{"name":"Department of Physiology, Faculty of Medicine Firat University Elazig Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,3,15]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"1","article-title":"Effects of fluoxetine on testis of albino rats\u2013a histological assessment","volume":"3","author":"Aggarwal A.","year":"2012","journal-title":"International Journal of Scientific & Engineering Research"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-015-4003-1"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1530\/rep.1.00598"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.4103\/1008-682X.192637"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2016.02.001"},{"key":"e_1_2_6_7_1","first-page":"321","article-title":"Effects of long\u2010term use of fluoxetine on fertility parameters in adult male rats","volume":"28","author":"Bataineh H. N.","year":"2007","journal-title":"Neuro Endocrinology Letters"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1080\/10401230500464612"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0736-4679(02)00522-X"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2012.00149"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1368-5031.2005.00681.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/jat.3089"},{"key":"e_1_2_6_13_1","first-page":"1","article-title":"Early\u2010life stress leads to sex\u2010dependent changes in pubertal timing in rats that are reversed by a probiotic formulation","author":"Cowan C. S.","year":"2018","journal-title":"Developmental Psychobiology"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2018.08.007"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2005.06.004"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1177\/1933719113477493"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/0269881107083798"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1530\/eje.1.02252"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.reprotox.2016.04.006"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1527-3458.2006.00178.x"},{"key":"e_1_2_6_21_1","first-page":"9","article-title":"Puberte Fizyolojisi","volume":"43","author":"Ercan G.","year":"2005","journal-title":"\u0130.\u00dc. Cerrahpa\u015fa T\u0131p Fak\u00fcltesi S\u00fcrekli T\u0131p E\u011fitimi Etkinlikleri Adolesan Sa\u011fl\u0131\u011f\u0131 Sempozyum Dizisi"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1677-5538.IBJU.2014.01.15"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1677\/joe.0.1390077"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.4088\/PCC.v07n0305"},{"issue":"12","key":"e_1_2_6_25_1","first-page":"1311","article-title":"Leptin levels reflect body lipid content in mice: Evidence for diet\u2010induced resistance to leptin action","volume":"1","author":"Frederich R. C.","year":"1995","journal-title":"NatureMedicine"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1159\/000054431"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2000.tb06210.x"},{"key":"e_1_2_6_28_1","first-page":"164","article-title":"Normal puberte geli\u015fimi ve puberte prekoks","volume":"40","author":"Gonc E.","year":"2009","journal-title":"Hacettepe T\u0131p Dergisi"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0272.1992.tb02617.x"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4757-3565-9"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1530\/ror.0.0020001"},{"key":"e_1_2_6_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0893-133X(00)00089-0"},{"key":"e_1_2_6_33_1","doi-asserted-by":"crossref","first-page":"16","DOI":"10.21608\/ejhm.2005.18045","article-title":"Toxic effects of paroxetine on sexual and reproductive functions of rats","volume":"21","author":"Inass E. G.","year":"2005","journal-title":"Egyptian Journal of Hospital Medicine"},{"key":"e_1_2_6_34_1","doi-asserted-by":"publisher","DOI":"10.4236\/asm.2014.42004"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.4111\/kju.2014.55.9.599"},{"key":"e_1_2_6_36_1","first-page":"106","article-title":"Effects of bupropion on physiology of reproduction in adult male rats","volume":"4","author":"Kankash A.","year":"2014","journal-title":"Journal of Applied Environmental and Biological Sciences"},{"key":"e_1_2_6_37_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/7.3.287"},{"key":"e_1_2_6_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-3057(99)00044-1"},{"key":"e_1_2_6_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-3057(03)00021-2"},{"key":"e_1_2_6_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.10.020"},{"key":"e_1_2_6_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2006.01.078"},{"key":"e_1_2_6_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2004.07.004"},{"key":"e_1_2_6_43_1","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1093\/clinchem\/42.6.942","article-title":"Radioimmunoassay of leptin in human plasma","volume":"42","author":"Ma Z.","year":"1996","journal-title":"Clinical Chemistry"},{"key":"e_1_2_6_44_1","doi-asserted-by":"publisher","DOI":"10.1179\/147683010X12611460764723"},{"key":"e_1_2_6_45_1","doi-asserted-by":"publisher","DOI":"10.1177\/1933719115578925"},{"key":"e_1_2_6_46_1","doi-asserted-by":"publisher","DOI":"10.1071\/RD12253"},{"key":"e_1_2_6_47_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-015-0436-2"},{"key":"e_1_2_6_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2006.04.018"},{"key":"e_1_2_6_49_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7827-8-138"},{"key":"e_1_2_6_50_1","first-page":"167","article-title":"Serum ghrelin and leptin levels in patients with depression and the effects of treatment","volume":"11","author":"Ozsoy S.","year":"2014","journal-title":"PsychiatryInvestigation"},{"key":"e_1_2_6_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0093-691X(99)00038-2"},{"issue":"5","key":"e_1_2_6_52_1","first-page":"668","article-title":"The timing of normal puberty and the age limits of sexual precocity: Variations around the world, secular trends, and changes after migration","volume":"24","author":"Parent A. S.","year":"2003","journal-title":"EndocrineReviews"},{"key":"e_1_2_6_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2014.08.004"},{"key":"e_1_2_6_54_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2005-0890"},{"key":"e_1_2_6_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2009.12.018"},{"key":"e_1_2_6_56_1","first-page":"121","article-title":"Cytogenetic and biochemical effects of antidepression drug (wellbutrin) on male mice","volume":"3","author":"Roshdy H. M.","year":"2010","journal-title":"New York Science Journal"},{"key":"e_1_2_6_57_1","doi-asserted-by":"publisher","DOI":"10.1097\/YIC.0000000000000023"},{"key":"e_1_2_6_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4530(99)00065-7"},{"key":"e_1_2_6_59_1","unstructured":"Smeets J. A. S.(2015).Timing of puberty\u2010Which factors trigger pulsatile GnRH release and the onset of puberty?(Masters thesis Utrecht University The Netherlands). Retrieved fromhttps:\/\/dspace.library.uu.nl\/handle\/1874\/311317"},{"key":"e_1_2_6_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2008.03.004"},{"key":"e_1_2_6_61_1","doi-asserted-by":"publisher","DOI":"10.1210\/endo.140.12.7194"},{"key":"e_1_2_6_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2006.10.034"},{"key":"e_1_2_6_63_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002130050443"},{"key":"e_1_2_6_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2007.12.006"},{"key":"e_1_2_6_65_1","doi-asserted-by":"publisher","DOI":"10.1210\/me.2005-0109"},{"key":"e_1_2_6_66_1","doi-asserted-by":"publisher","DOI":"10.1111\/and.12980"}],"container-title":["Andrologia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/and.13268","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/and.13268","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/and.13268","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T12:38:50Z","timestamp":1671539930000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/and.13268"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3,15]]},"references-count":65,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2019,3,28]]},"published-print":{"date-parts":[[2019,7]]}},"alternative-id":["10.1111\/and.13268"],"URL":"https:\/\/doi.org\/10.1111\/and.13268","archive":["Portico"],"relation":{},"ISSN":["0303-4569","1439-0272"],"issn-type":[{"value":"0303-4569","type":"print"},{"value":"1439-0272","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3,15]]}}}