{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T13:29:40Z","timestamp":1791725380286,"version":"4.3.4"},"reference-count":109,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2020,4,23]],"date-time":"2020-04-23T00:00:00Z","timestamp":1587600000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2020,4,23]],"date-time":"2020-04-23T00:00:00Z","timestamp":1587600000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Andrologia"],"published-print":{"date-parts":[[2021,2]]},"DOI":"10.1111\/and.13581","type":"journal-article","created":{"date-parts":[[2020,4,23]],"date-time":"2020-04-23T03:49:15Z","timestamp":1587613755000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":107,"title":["Oxidative stress in the pathophysiology of male infertility"],"prefix":"10.1155","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0656-7940","authenticated-orcid":false,"given":"Cayde","family":"Ritchie","sequence":"first","affiliation":[{"name":"Department of Urology Loma Linda University Loma Linda CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7465-3616","authenticated-orcid":false,"given":"Edmund Y.","family":"Ko","sequence":"additional","affiliation":[{"name":"Department of Urology Loma Linda University Loma Linda CA USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,4,23]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.reprotox.2007.10.004"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/diseases5010009"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/jncimonographs\/lgi005"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2007.04.011"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.4103\/aja.aja_5_19"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.5534\/wjmh.190055"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2005.05328.x"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2006.02.088"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12958-015-0007-2"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.4103\/1008-682X.153848"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1071\/RD9940019"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1939-4640.2000.tb02113.x"},{"issue":"6","key":"e_1_2_9_14_1","first-page":"287","article-title":"Not every sperm is sacred; a perspective on male infertility","volume":"24","author":"Aitken R. J.","year":"2018","journal-title":"Molecular Human Reproduction"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1939-4640.1988.tb01067.x"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.2164\/jandrol.112.016535"},{"key":"e_1_2_9_17_1","first-page":"109","article-title":"Maturation of redox regulatory mechanisms in the epididymis","volume":"53","author":"Aitken R. J.","year":"1998","journal-title":"Journal of Reproduction and Fertility. Supplement"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod29.3.548"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod32.2.342"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1530\/REP-13-0178"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2011.05.026"},{"key":"e_1_2_9_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1939-4640.1999.tb03375.x"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2010.06.146"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/WOX.0b013e3182439613"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrurol.2017.69"},{"key":"e_1_2_9_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dev214"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/deh280"},{"issue":"1","key":"e_1_2_9_28_1","first-page":"E1","article-title":"Nerve blood flow in early experimental diabetes in rats: Relation to conduction deficits","volume":"261","author":"Cameron N. E.","year":"1991","journal-title":"American Journal of Physiology"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.00210"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2005.11.018"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-011-9602-0"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.4103\/1008-682X.178486"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2003.11.002"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2009.05.025"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7827-10-109"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.4103\/1008-682X.126384"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1745-7262.2008.00417.x"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11255-015-1053-6"},{"key":"e_1_2_9_39_1","first-page":"523","article-title":"The redox system in human semen and peroxidative damage of spermatozoa","volume":"59","author":"Fraczek M.","year":"2005","journal-title":"Postepy Hig Med Dosw (Online)"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.115.129759"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0272.1981.tb00002.x"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/15.9.1953"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2605.1998.00106.x"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1111\/andr.12074"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2015.05.014"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1677-55382012000500002"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.5b00407"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1620\/tjem.218.141"},{"key":"e_1_2_9_49_1","volume-title":"Oxidants, antioxidants, and impact of the oxidative status in male reproduction","author":"Henkel R.","year":"2018"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.1242\/dev.136721"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.3109\/01485019808987929"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.3390\/genes10030236"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.5812\/ircmj.6409"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.2.23"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/2.8.613"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod64.2.674"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2015.04.037"},{"key":"e_1_2_9_58_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijir.3901523"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)43999-3"},{"issue":"3","key":"e_1_2_9_60_1","first-page":"227","article-title":"Influence of selenium induced oxidative stress on spermatogenesis and lactate dehydrogenase\u2010X in mice testis","volume":"6","author":"Kaur P.","year":"2004","journal-title":"Asian Journal of Andrology"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20110114"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1038\/npjgenmed.2016.23"},{"key":"e_1_2_9_63_1","doi-asserted-by":"publisher","DOI":"10.4103\/0971-6866.60183"},{"key":"e_1_2_9_64_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep32916"},{"key":"e_1_2_9_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.repbio.2017.05.010"},{"key":"e_1_2_9_66_1","doi-asserted-by":"publisher","DOI":"10.2174\/1381612822666161019150241"},{"key":"e_1_2_9_67_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4614-7783-9_7"},{"key":"e_1_2_9_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(16)57306-3"},{"key":"e_1_2_9_69_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1439-0272.1998.tb01374.x"},{"key":"e_1_2_9_70_1","doi-asserted-by":"publisher","DOI":"10.1080\/00071660903401540"},{"key":"e_1_2_9_71_1","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/7893961"},{"issue":"4","key":"e_1_2_9_72_1","article-title":"Antioxidants and male fertility: From molecular studies to clinical evidence","volume":"8","author":"Martin\u2010Hidalgo D.","year":"2019","journal-title":"Antioxidants (Basel)"},{"key":"e_1_2_9_73_1","doi-asserted-by":"publisher","DOI":"10.1111\/and.13267"},{"key":"e_1_2_9_74_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.108.184325"},{"key":"e_1_2_9_75_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2605.2001.00296.x"},{"key":"e_1_2_9_76_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.107.061242"},{"key":"e_1_2_9_77_1","doi-asserted-by":"publisher","DOI":"10.1002\/mrd.1080280408"},{"issue":"3","key":"e_1_2_9_78_1","first-page":"403","article-title":"Sperm mitochondrial dysfunction and oxidative stress as possible reasons for isolated asthenozoospermia","volume":"69","author":"Nowicka\u2010Bauer K.","year":"2018","journal-title":"Journal of Physiology and Pharmacology"},{"key":"e_1_2_9_79_1","doi-asserted-by":"publisher","DOI":"10.1186\/2051-4190-24-4"},{"key":"e_1_2_9_80_1","doi-asserted-by":"publisher","DOI":"10.2164\/jandrol.111.015388"},{"key":"e_1_2_9_81_1","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.110.085712"},{"key":"e_1_2_9_82_1","doi-asserted-by":"publisher","DOI":"10.1080\/19396360802415752"},{"key":"e_1_2_9_83_1","doi-asserted-by":"publisher","DOI":"10.3109\/01485019608987090"},{"key":"e_1_2_9_84_1","doi-asserted-by":"publisher","DOI":"10.4103\/1008-682X.122194"},{"key":"e_1_2_9_85_1","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/gag037"},{"key":"e_1_2_9_86_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/4.1.3"},{"key":"e_1_2_9_87_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1743-6109.2005.20103.x"},{"key":"e_1_2_9_88_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-879X2005000700003"},{"key":"e_1_2_9_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2006.11.100"},{"key":"e_1_2_9_90_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.09-132795"},{"key":"e_1_2_9_91_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7827-11-48"},{"issue":"2","key":"e_1_2_9_92_1","first-page":"139","article-title":"Sperm DNA damage and its clinical relevance in assessing reproductive outcome","volume":"6","author":"Sharma R. K.","year":"2004","journal-title":"Asian Journal of Andrology"},{"key":"e_1_2_9_93_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aad6780"},{"key":"e_1_2_9_94_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1939-4640.1999.tb03376.x"},{"key":"e_1_2_9_95_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1993.tb18025.x"},{"key":"e_1_2_9_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2015.01.002"},{"key":"e_1_2_9_97_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-62703-038-0_13"},{"issue":"1","key":"e_1_2_9_98_1","first-page":"28","article-title":"Male infertility: Nutritional and environmental considerations","volume":"5","author":"Sinclair S.","year":"2000","journal-title":"Alternative Medicine Review: A Journal of Clinical Therapeutic"},{"key":"e_1_2_9_99_1","doi-asserted-by":"publisher","DOI":"10.1590\/s1677-5538.ibju.2016.0323"},{"key":"e_1_2_9_100_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/del292"},{"key":"e_1_2_9_101_1","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.898631"},{"key":"e_1_2_9_102_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/dev053"},{"key":"e_1_2_9_103_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph6020445"},{"key":"e_1_2_9_104_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/7460453"},{"key":"e_1_2_9_105_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.04-2513fje"},{"key":"e_1_2_9_106_1","doi-asserted-by":"publisher","DOI":"10.1038\/aja.2009.26"},{"key":"e_1_2_9_107_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-5491.2000.00259.x"},{"key":"e_1_2_9_108_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2012.06.021"},{"key":"e_1_2_9_109_1","doi-asserted-by":"publisher","DOI":"10.1530\/REP-07-0576"},{"key":"e_1_2_9_110_1","doi-asserted-by":"publisher","DOI":"10.2164\/jandrol.108.006908"}],"container-title":["Andrologia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fand.13581","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/and.13581","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/and.13581","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/and.13581","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T07:36:43Z","timestamp":1671521803000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/and.13581"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,23]]},"references-count":109,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["10.1111\/and.13581"],"URL":"https:\/\/doi.org\/10.1111\/and.13581","archive":["Portico"],"relation":{},"ISSN":["0303-4569","1439-0272"],"issn-type":[{"value":"0303-4569","type":"print"},{"value":"1439-0272","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4,23]]},"assertion":[{"value":"2020-01-08","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-03-03","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-04-23","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}