{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T03:05:43Z","timestamp":1792206343914,"version":"4.4.0"},"reference-count":51,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2021,7,4]],"date-time":"2021-07-04T00:00:00Z","timestamp":1625356800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2021,7,4]],"date-time":"2021-07-04T00:00:00Z","timestamp":1625356800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Andrologia"],"published-print":{"date-parts":[[2021,10]]},"DOI":"10.1111\/and.14181","type":"journal-article","created":{"date-parts":[[2021,7,5]],"date-time":"2021-07-05T02:34:56Z","timestamp":1625452496000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":37,"title":["Effects of lead, cadmium, copper and zinc levels on the male reproductive function"],"prefix":"10.1155","volume":"53","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9872-8862","authenticated-orcid":false,"given":"Ines","family":"Chabchoub","sequence":"first","affiliation":[{"name":"Laboratory of Toxicology and Environment Medical and Emergency Assistance Center  Tunis Tunisia"},{"name":"Department of Genetics The Faculty of Pharmacy Monastir  Monastir Tunisia"},{"name":"Laboratory of Reproductive Biology Center of Reproductive Medicine and Prenatal Diagnosis  Tunis Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed Anouar","family":"Nouioui","sequence":"additional","affiliation":[{"name":"Laboratory of Toxicology and Environment Medical and Emergency Assistance Center  Tunis Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manel","family":"Araoud","sequence":"additional","affiliation":[{"name":"Laboratory of Toxicology and Environment Medical and Emergency Assistance Center  Tunis Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mahmoud","family":"Mabrouk","sequence":"additional","affiliation":[{"name":"Laboratory of Toxicology and Environment Medical and Emergency Assistance Center  Tunis Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorra","family":"Amira","sequence":"additional","affiliation":[{"name":"Laboratory of Toxicology and Environment Medical and Emergency Assistance Center  Tunis Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed Habib","family":"Ben Aribia","sequence":"additional","affiliation":[{"name":"Laboratory of Reproductive Biology Center of Reproductive Medicine and Prenatal Diagnosis  Tunis Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khaled","family":"Mahmoud","sequence":"additional","affiliation":[{"name":"Laboratory of Reproductive Biology Center of Reproductive Medicine and Prenatal Diagnosis  Tunis Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fethi","family":"Zhioua","sequence":"additional","affiliation":[{"name":"Assisted Reproduction Unit Department of Gynecology and Obstetrics Aziza Othmana Hospital  Tunis Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghaya","family":"Merdassi","sequence":"additional","affiliation":[{"name":"IVF Center Alyssa Fertility Group  Tunis Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abderrazek","family":"Hedhili","sequence":"additional","affiliation":[{"name":"Laboratory of Toxicology and Environment Medical and Emergency Assistance Center  Tunis Tunisia"},{"name":"Department of Genetics The Faculty of Pharmacy Monastir  Monastir Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2021,7,4]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12958-015-0032-1"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.4103\/aja.aja_5_19"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2016.10.008"},{"issue":"1","key":"e_1_2_8_5_1","first-page":"17","article-title":"Cadmium toxicity: A possible cause of male infertility in Nigeria","volume":"6","author":"Akinloye O.","year":"2006","journal-title":"Reproductive Biology"},{"issue":"1","key":"e_1_2_8_6_1","first-page":"1","article-title":"Saffron improves epididymal sperm parameters in rats exposed to cadmium","volume":"6","author":"Asadi M. H.","year":"2014","journal-title":"Nephro\u2010Urology Monthly"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2605.1990.tb01052.x"},{"key":"e_1_2_8_8_1","volume-title":"Sperm chromatin structure, semen quality and lead in blood and seminal fluid of infertile men","author":"Awadalla N. J.","year":"2011"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1385\/BTER:112:3:193"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2013.05.004"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/der129"},{"key":"e_1_2_8_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/oem.59.4.234"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2011.10.006"},{"key":"e_1_2_8_14_1","doi-asserted-by":"publisher","DOI":"10.3109\/01485019208987722"},{"issue":"3","key":"e_1_2_8_15_1","first-page":"215","article-title":"The protective effect of Costus afer Ker Gawl aqueous leaf extract on lead\u2010induced reproductive changes in male albino Wistar rats","volume":"23","author":"Ezejiofor A. N.","year":"2019","journal-title":"JBRA Assisted Reproduction"},{"issue":"3","key":"e_1_2_8_16_1","first-page":"405","article-title":"Relationship of blood and semen lead level with semen parameter","volume":"19","author":"Fatima P.","year":"2010","journal-title":"Mymensingh Medical Journal"},{"issue":"3","key":"e_1_2_8_17_1","first-page":"537","article-title":"Association of blood and semen lead and zinc level with semen parameter in the male partner of infertile couple","volume":"24","author":"Fatima P.","year":"2015","journal-title":"Mymensingh Medical Journal"},{"key":"e_1_2_8_18_1","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2017.6381"},{"key":"e_1_2_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rbmo.2015.10.009"},{"key":"e_1_2_8_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1383-5718(02)00012-8"},{"key":"e_1_2_8_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10815-017-0912-8"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.reprotox.2005.01.007"},{"key":"e_1_2_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.reprotox.2005.07.015"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1093\/humupd\/dml056"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2008.01.005"},{"issue":"3","key":"e_1_2_8_26_1","first-page":"545","article-title":"Reference range of zinc in adult population (20\u201329 years) of Lahore, Pakistan","volume":"30","author":"Hussain W.","year":"2014","journal-title":"Pakistan Journal of Medical Sciences"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1080\/09603123.2014.958137"},{"key":"e_1_2_8_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/occmed\/kql116"},{"key":"e_1_2_8_29_1","doi-asserted-by":"publisher","DOI":"10.1080\/10937404.2019.1592728"},{"key":"e_1_2_8_30_1","first-page":"193","article-title":"Lead exposure and oxidative stress: A systematic review","volume":"236","author":"Lopes A. C. B. A.","year":"2016","journal-title":"Reviews of Environmental Contamination and Toxicology"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aju.2017.11.014"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.3390\/toxics8040094"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.11490"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2008.09.044"},{"issue":"1","key":"e_1_2_8_35_1","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/1476-069X-10-6","article-title":"Relationships between heavy metal concentrations in three different body fluids and male reproductive parameters: A pilot study","volume":"10","author":"Mendiola J.","year":"2011","journal-title":"Environmental Health: A Global Access Science Source"},{"key":"e_1_2_8_36_1","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/420893"},{"key":"e_1_2_8_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2015.06.005"},{"key":"e_1_2_8_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-019-04209-y"},{"key":"e_1_2_8_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0890-6238(03)00036-4"},{"key":"e_1_2_8_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(02)03105-9"},{"key":"e_1_2_8_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2007.05.011"},{"key":"e_1_2_8_42_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.0010845"},{"key":"e_1_2_8_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1472-6483(10)60308-2"},{"key":"e_1_2_8_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.envint.2016.05.022"},{"key":"e_1_2_8_45_1","doi-asserted-by":"publisher","DOI":"10.4038\/cmj.v60i2.7090"},{"key":"e_1_2_8_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0890-6238(01)00113-7"},{"key":"e_1_2_8_47_1","volume-title":"WHO laboratory manual for the examination and processing of human semen","author":"World Health Organization","year":"2010"},{"key":"e_1_2_8_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.reprotox.2008.04.005"},{"key":"e_1_2_8_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0890-6238(96)00108-6"},{"key":"e_1_2_8_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2007.12.016"},{"key":"e_1_2_8_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2007.04.028"},{"key":"e_1_2_8_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.etap.2016.05.020"}],"container-title":["Andrologia"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/and.14181","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/and.14181","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/and.14181","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,20]],"date-time":"2022-12-20T12:38:32Z","timestamp":1671539912000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/and.14181"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,4]]},"references-count":51,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["10.1111\/and.14181"],"URL":"https:\/\/doi.org\/10.1111\/and.14181","archive":["Portico"],"relation":{},"ISSN":["0303-4569","1439-0272"],"issn-type":[{"value":"0303-4569","type":"print"},{"value":"1439-0272","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,4]]},"assertion":[{"value":"2021-03-22","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-06-17","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}